UCSF study offers insight into human circadian rhythms
...family members who did not have FASPS.) Next, they determined that, in a test tube, the activity of the enzyme (CK1 delta) encoded by the mutated gene was decreased. Finally, to explore the effect of the genetic mutation on circadian activity, the scientists inserted the mutated human gene into the nerve cells ...Early onset of puberty the EU gets serious
...ing a major three-year project called PIONEER in a determined effort to get to the root of the problem. Two Swed...rom Karolinska Institutet. The onset of puberty is determined by a string of factors, such as environment, physiology and heredity, but just how they interact rem...Optical technique identifies vulnerable plaques in cardiac patients
...and the characteristics of those plaques have been determined primarily by autopsy studies. OCT uses infrared light delivered via fiberoptic catheter to produce high-resolution, cross-sectional images of blood vessels. Study co-authors Guillermo Tearney, MD, PhD, of the MGH Pathology Department and the Wellma...Some brain cells 'change channels' to fine-tune the message
...d mice. Through their experiments, the researchers determined that the PICK1 and NSF proteins are both required for the calcium-forbidding channel to move into place at the synapse. Exactly how they help the channels move is still unknown, as is why the cells change their channels. Part of the answer is likely ...Boston University team finds link between high cholesterol and better cognitive performance
...s for cognitive function. Scientists have not yet determined whether lowering cholesterol with medication will influence mental functioning. "The result of lowering cholesterol with current medications may be very different from naturally low cholesterol," said Merrill Elias. "We certainly need to evaluate wh...Epidemiologist Trichopoulos receives $5.8 million Department of Defense 'Innovator Award'
... is not reflected in breast size, which is largely determined by body fat. The theory is supported by evidence presented in epidemiologic studies that indicate certain early-life conditions, such as large birth size, are associated with breast cancer risk. In addition, correlates of mammary gland mass, such as ...Employees with diabetes are not more tired
...althier. The burdensomeness experienced is in part determined by how competent an individual feels about carrying out these tasks. Weijman discovered that tired employees with diabetes also have a different outlook on their disease and their work situation. They were more likely to find flexibility in the work...Mechanism of RNA recoding: New twists in brain protein production
... on such targets, but didn't explain how they were determined or how they may have evolved. His new study does both. By comparing the same highly edited RNA from over 30 insects, Reenan uncovered some general rules of A-to-I recoding. He observed that the RNA of different insects folds into unique structures. T...Risk of cardiac death after radiotherapy for breast cancer has declined, study finds
...adiotherapy has been entirely eliminated cannot be determined definitely from this study. Continued follow-up of the women diagnosed and treated in the late 1980s will be necessary to answer this question," the authors write. In an editorial, Jack Cuzick, Ph.D., of Cancer Research U.K. in London, discusses the ...Mayo Clinic discovers 'new pathway' against pancreatic cancer
...ct the opposite of what we found. But in fact, we determined that we can decrease a known regulator of cancer c...ncreatic cancer for the GSK-3 Beta molecule. They determined that GSK-3 Beta is vital to pancreatic cancer cell survival and growth through its effects on a well...Study shows acrylamide in baked and fried food does not increase risk of breast cancer in women
...Lifestyle and Health Cohort. Acrylamide intake was determined from food frequency questionnaires reported by the women in 1991; the women's health status was tracked via national health registers until the end of 2002. The average daily acrylamide intake among the participants was 25.9 micrograms per day. Less...Balance and better interactions between primary-care and specialist physicians improve US health
... ratio did not decrease mortality rates. They also determined that too many specialists would negatively impact communities because more patients would be seen by specialists and would be more likely to receive unnecessary tests and procedures. The researchers report that, in the United States, the boundaries ...Obesity among African-American stroke survivors increases risk factors for recurrent stroke
...aseline data on height and weight, the researchers determined the body mass index (BMI, calculated as weight in kilograms divided by the square of height in meters) for 1,711 patients. The patients were divided into six groups, underweight (BMI less than 18.5), normal weight (BMI 18.5 24.9), overweight ((BMI 2...Orchestra pit no danger to hearing
...a risk to their hearing." Behar and his team first determined through the personnel manager that the musicians play for 300 work hours per year, including performances and rehearsals. They then tested 67 volunteers who were requested to wear a noise dosimeter a small cigarette-sized instrument used to measure ...Chemicals in tattoo inks need closer scrutiny
...of compounds. "At this point in the study, we have determined that the inks do in fact vary in composition from manufacturer to manufacturer and from color to color," Wagner says. The researchers also have found some indication of the presence of metals, and are in the process of running more tests to verify th...Sex selection popular among infertile women
... desire for boys over girls." The researchers also determined that women with only daughters wanted to select a male child, and women with only sons wanted to select a female child. Non-white racial groups had a stronger preference for sex selection, according to the study. Women who were older, not religious, ...2005 Craniofacial Biology Research Award
...on of the mandibular symphysis and brow ridges and determined correlations between muscle activity and bone deformation. The techniques and approaches he developed have been widely applied in craniofacial biology, and his eminence has already been recognized by a variety of awards, including the highly prized M...Researchers discover link between insulin and Alzheimer's
...l regions in the brain. Additionally, researchers determined that a drop in insulin production in the brain contributes to the degeneration of brain cells, an early symptom of Alzheimer's. "These abnormalities do not correspond to Type 1 or Type 2 diabetes, but reflect a different and more complex disease proc...Studies underscore genetic involvement in nicotine addiction & aggressive hostility
...tic profile' of the smoker." The authors similarly determined that Chrna4 does not directly regulate alcohol intake because removal of Chrnb2, a gene whose protein partners with the Chrna4 protein, does not affect the relationship between Chrna4 and alcohol consumption. Therefore, Chrna4 may be associated with......re widely available. The Hopkins team successfully determined new cases from old by adding the Affinity/Avidity test to the current STARHS protocol, the test widely used by the United States Centers for Disease Control and Prevention. This second test measures the strength of antibody-antigen binding in the im...