DNA Imaging to Design Better Drugs
...ster than traditional methods, and the results are direct andrelatively simple to interpret. "Our technique directly visualizes individual DNA molecules, whiletraditional techniques are indirect and inferential, sometimes givinginexplicable results," said Dr. Loren Williams, an associate professorin Georgi......come hopelessly jumbled," she says. "We can accept direct messages of no-alcohol and no-drug use. But when it comes to sex we rely on hidden messages. We believe that if we talk about condoms, birth control and safe sex with our children we are giving an inferred message that it is OK to have sex. We can't ...Common Drug-Capsule Coating Not As Inert As Previously Thought
...s in the design of biomaterials is that thereis no direct correlation between a material's properties and its biocompatibility,Leckband said. "Because of its apparent low toxicity and apparentinertness, PEG has served as a working model for the design of other surfacecoatings. But if your assumptions abou...Princeton Plasma Physics Laboratory collaborates with USDA in development of pasteurization process
...n method of directly heating raw liquid foods. The direct method often heats foods unevenly, possibly resulting in incomplete pasteurization in lower temperature regions and in denaturing foods in overheated regions. Using radio frequency waves in the appropriate wavelength may allow pasteurization without ...Cardiovascular Costs, Deaths Projected To Rise In 1998
...ated at $119.9 billion - is the largestcategory of direct costs. Physician and other professional services account foranother $25.9 billion. Among indirect costs, the American Heart Associationestimates that lost productivity resulting from deaths from cardiovasculardisease will cost the United States $77.9...Radon, Especially In Combination With Smoking, Contributes To Lung Cancer Deaths
...ation studied was all male. The most direct way to assess the effects of radon in homes would be to compare the levels of radon exposure among people who have lung cancer with those who do not. Such studies have not yet provided a definitive answer, the committee said, because levels of radon..."Powerful New Tool" For AIDS Is Reported In Science
...ole universe of clinical and research questions to direct measurement." Initial in vivo results are the first step in the development process of this diagnostic technology. SpectruMedix is a U.S. company with a strong focus on medical and scientific technologies and associated instrumentation. It manufactu...UCSF Hospitalists May Be Key To Shorter, Less Costly Hospital Stays
... "What you have with the hospitalist model is more direct supervision byindividuals who are more experienced in this attending role, more skilled in itand for whom this role is a larger part of their professional identity," saidRobert M. Wachter, MD, UCSF associate professor of medicine and epidemiology. W...New Treatment Targets Most Malignant Brain Tumors
...them. Other groups have attempted the same direct injection technique withlittle success, said Bigner, but they used different radioactive isotopes,different antibodies and less effective surgical techniques to seal the cavitiesfrom the circulating cerebrospinal fluid. Antibodies are protein......m." "The highly specific drug therapy is a direct extension of our lab workon CML," said Druker. "Our studies have revealed that the BCR-ABL protein is theobvious abnormality to attack in CML." Druker stressed that the development of this new cancer- fighting drugrepresents an example of the...Six Football Players Died In 1997 Season: New Study
...nts --died across the United States last year as a direct result of injuries sufferedon the field, a new University of North Carolina at Chapel Hill study shows.Eight other players also died, but those fatalities were not directly tied tothe game and could have resulted from other vigorous activities. .......3 percent or $50per member per month reduction in direct health care costs, according to a studypublished today in the Journal of Clinical Endocrinology and Metabolism. Forhealth plans, this translates into an average savings of $600,000 per 1,000members with diabetes in the first year of operation. This......r's symptoms. "Our finding, however, is the first direct evidence ofa targeted dopamine deficit in adults with ADHD," says the study's lead author,Monique Ernst, MD, PhD, Senior Staff Fellow at the National Institutes ofHealth. "We found that the activity of an enzyme involved in the production ofthe chem...Alzheimers Disease Could Soon Be Treated With Nose Drops
... into the brain, as the olfactorysystem provides a direct link between the brain and the outside world. Getting drugs into the brain is one of neuroscience's challenges. Themolecules of many drugs are too large to cross the blood-brain barrier, thetightly woven cells in the blood vessels in and arou...The European Medicines Evaluation Agency: Open To Criticism
...ntralised procedure allows applications to be made direct to the EMEA so that drugs can be made available throughout the European Union. Alternatively companies can apply to national licensing authorities, which ensures that product licences granted in one country receive mutual recognition in other member...AIDS Prevention: Does It Work? Paper Suggests New Way To Assess Prevention Programs
... risk but also actual changes in behavior - a more direct indicator oflikeliness to contract or avoid contracting HIV. The researchers argue thatmeasuring the number of people who have developed HIV, and not just the numberof people reached through prevention programs, is a marked improvement indetermining ......r normal pregnancies than might havebeen lost as a direct consequence of invasive procedures," said EugenePe...ir unwillingess to risk loss of the pregnancy as a direct consequence ofperforming either procedure," Pergament said. Pregnant women under 35 can hav......ogy Department has discovered that there is indeed direct communication between the nervous and immune systems. In a study reported recently in the PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, she showed for the first time that neurotransmitters can "order" cytokine secretion from T cells. This may help...American Psychiatric Association Tipsheet - December
...M.P.H., et.al., p. 1775] APAfastFAX# 6901. Please direct mediainquiries to Dr. Druss at benjamin_druss@yal...s Hurley, Ph.D., p. 1618] APAfastFAX# 6903 Please direct mediainquiries to Dr. Hurley, 617-636-8763; e-mail, hurleyannd@aol.com .......uter-controlledsuperconducting magnets to remotely direct a small flexible biopsy instrumentinto the patient...re innovative indelivering electrodes or drugs for direct therapy of a variety of braindiseases." The following visuals are available: The Magnetic Surgery S...