Tag: "discovery" at medical news

Compound That Mimics Insulin Might Lead To Pill For Diabetes, As Reported In The 7 May Issue Of Science

...ke such a pilleffective. This new substance, whose discovery is reported in the 7 May issue of Science , appears to mimic the effects of insulin, at least in mice--but,unlike insulin, it can be swallowed instead of injected. A pill developed fromthis substance could be a welcome alternative to the insulin inje...

Wistar scientist awarded American Cancer Society grant for research on tumor killing cells

...egastroenteritis (rotavirus), and cytomegalovirus; discovery of molecules likeinterleukin-12, which are helping the immune system fight bacteria, parasites,viruses and cancer; and location of genes that contribute to the development ofdiseases like breast, lung and prostate cancer. Wistar is a National Cancer...

Irritable Bowel Syndrome The Focus Of Three UNC-CH Reports At Digestive Diseases Conference

... during adulthood. "Physicians shouldrecognize the discovery of abuse in IBS patients as a marker that the patientis at significant risk for depression and suicide," Whitehead says. "Thesepatients may require assessment and perhaps referral to mental health services." The study analyzed questionnaire ...

Transplant Pioneer Thomas E. Starzl Most Cited Researcher In Clinical Medicine Over Past 17 Years

...s continued toadvance the field considerably. His discovery in the early 1980s that the drugcocktail prednisone, azathioprine and cyclosporine could control organ rejectionpractically transformed the field overnight, making it more feasible totransplant livers, kidneys and hearts. In 1989, he and his team an...

Progress In Cancer-Vaccine Studies: Simpler, Safer Approach Producing Encouraging Results

... of Clinical Oncology in Atlanta, was the surprise discovery thatmoderate doses of IL-12 were far more effective at stimulating an anti-cancerresponse than higher, more-toxic doses. Phase-1 clinical trials are usually designed to determine the maximum tolerateddose of a new drug, but this trial indicated that ...

Treating Depression Makes A Healthier Heart

...nt heartdisease. The scientists who have made this discovery think that improved moodmakes the difference, rather than direct action by the drugs. People who suffer from severe depression are up to four times as likelyto die from heart disease triggered by obstructed blood flow as people who arenot dep...

Scientist explain a drug's paradoxical action: discovery may lead to new therapies for breast cancer, early puberty

...T CELLS AS LITTLE ADRENAL GLANDS Lee's and Auchus' discovery actually was a small part of a much larger project,undertaken in the Miller lab under Auchus' initiative. The group has developed astrain of "humanized" yeast that express the DNA of human enzymes. They plan touse yeast cells, converted into little v...

AAPS Symposium to present latest developments in Cheminformatics

... chair of thesymposium's planning committee. "All discovery scientists must use a variety ofthese technologies to manage and communicate their research results, and in manycases, these can replace traditional chemistry." This symposium will combine information technology topics with drug discoveryissues and r...

Researchers discover the driving force behind cancer cells in Hodgkin's disease

...from thedisease itself." Researchers hope that the discovery of IL-13's role in Hodgkin's tumourprogression will help them to develop targeted treatments for the disease thatcause few, if any, side effects. Rather than subjecting Hodgkin's patients topotentially harmful chemicals or radiation, researchers hop...

Scientists use bacterial toxin to kill brain tumors

...s each year in Canadaand the United States. "This discovery could be very promising because theverotoxin makes a two-pronged attack on the tumor: it destroys tumor cells andshuts down the tumor's blood supply." While earlier HSC research has demonstrated that verotoxin-producing E. coli cancause kidney failur...

Depression-treating drugs lead record-setting pharmacy benefit cost rise -- Total increase lower when pharmacy benefit actively managed

...nd maintain access to pharmacy benefitsdespite the discovery of more innovative drugs, faster FDA approvals and morewidespread direct-to-consumer marketing, according to Toan. Last year's annual per member cost -- on an average wholesale price (AWP) basisbefore copayments, discounts and active management -- w...

Allergy-producing cells are also 'do-gooders,' helping stave off infections

..., are the mast cells alerted. The Duke scientists' discovery also appears to clear up a mystery about thefunction of the CD48 protein. Although CD48 was discovered more than 10 yearsago as a protein that appears on the surface of some white blood cells such asmast cells, its biological role has not been clearl...

Vanderbilt University Medical Center designated as one of three Glaxo Wellcome Genetic Epidemiology Centers

...rstand the biology of the disease will lead to the discovery ofbetter drug targets and the development of more effective drugs." Haines helped Glaxo Wellcome develop its plan for setting up Clinical GeneticsNetworks to search for the genetic basis of common diseases. "I have known and collaborated with Jonatha...

UK researcher develops nicotinic drugs with R.J. Reynolds

...ram. The partnership with the therapeutics discovery group, now calledTargacept, has resulted in several potential drug candidates being evaluated forclinical trials. Nicotine is the addictive ingredient in tobacco products that keeps manyusers hooked, but during the past several years, resear...

Thunderstorms shed light in mystery of epileptic seizures

...the Toronto Western Hospital. The study marks the discovery of the occurrence of a particular dynamic regime-- type III intermittency -- that takes place during seizures in patients withintractable epilepsy, a form of the disease that cannot be treated withmedication. Intermittency is characterized by regular...

Duke/Novalon researchers identify potential mechanism behind tamoxifen resistance in breast cancers

...who use it for more than five years. Theysay their discovery could lead to new drugs that either work better th...ke's cutting edge basic science and Novalon's drug discovery program," saidDana M. Fowlkes, chairman and chief scientific officer of Novalon. "We weredelighted t...

UI researchers identify prostate tumor suppressor

...ncer cells. When directly applied to patients,this discovery raises great hope of limiting the spread of prostate cancerwithin the body and thus improving survival."...

New anti-angiogenic proteins discovered

...cientists at UCLA and Human Genome Sciences report discovery of two human proteins, METH-1 and METH-2, that inh...reatments for a broad range of tumor types. The discovery of these two proteins and their anti-angiogenic activity isdescribed in the August 13, 1999 issue of...

NSF award to five Georgia universities for new Science and Technology Center

...e STC. In addition to providing fertile ground for discovery on the frontiers ofneuroscience, the STC will furnish invaluable learning opportunities for Georgiafaculty and students at all levels of the educational pipeline. As home to thehighest density of minority colleges in the country, Atlanta is well posi...

LSU scientist says new drug will save brain cells attacked by neurological injury or disease

...process before the genes can be affected. Bazan's discovery of a novel mechanism to inhibit the expression of pathologicalgenes led to the development, in collaboration with organic chemists, of a drugthat renders these genes inactive in animal models of neurodegenerative disease. His laboratory will now ente...

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