Tag: "discovery" at medical news

Nortran Pharmaceuticals Inc. and Hoechst Marion Roussel announce collaborativeagreement

...ran Pharmaceuticals is a commercially-focused drug discovery company. Usingpathology-targeted molecules, Nortran focuses on developing treatments forserious medical conditions and illnesses affecting large numbers of people. Nortran's current drugs in development target life-threatening arrhythmias ofthe heart...

Why prostate cancer homes to bone

.... This finding has important implications for the discovery anddevelopment of agents that might be used in the treatment of prostate cancer andother cancers that spread to bone. Prostate cancer is the second leading cause of cancer deaths in men from bothEurope and the United States. At the time of diagnosis...

Cancer tumors shown to consume large amounts of vitamin C

...he vitamin is converted back toascorbic acid. This discovery prompted Dr. Golde's team to explore whether glucose transportermolecules and vitamin C might function in cancer cells, as malignant cellsdevour more glucose than normal cells to obtain the energy they need to grow. Subsequently, their laboratory stu...

UCSF finding could lead to a new class of painkillers

...ct the finding will apply even more broadly. "This discovery is extremely important," said the director of the National Institutes of Health Pain Center at UCSF, Jon Levine, PhD, a professor of oral and maxillofacial surgery and medicine and a senior author of the paper. "I think this signaling pathway will b...

University of Maryland announces $24 million research initiative to find new treatments for schizophrenia

...n psychiatricpharmaceutical research marked by the discovery and introduction of breakthroughtherapies such as the antipsychotic MellerilR (thioridazine) in the 1950's, andthe schizophrenia drug LeponexR/ClozarilR (clozapine) in the 1970s. Zomaril(iloperidone), a new antipsychotic currently in clinical devel...

UCSF researchers discover new piece of puzzle in cancer development

...s and prognosis, and a new target for therapy. The discovery centers on fibroblasts, cells that help form the supportive basesurrounding epithelial cells - which line the glands, ducts and surfaces oforgans, such as the breast, colon and stomach, and are the cells from whichmost cancers arise. Using cells deri...

Gene responsible for cerebral venous abnormalities found

...ause massive brain hemorrhages.The scientists said discovery of a cerebral cavernous malformations (CCM) genecould herald important medical advances for individuals and families with thiscondition--especially for the Mexican-American community, which appears to showa higher incidence of CCM than other ethnic g...

NICHD funded researchers discover gene for Rett syndrome

...e," said NICHD Director Duane Alexander, M.D. "The discovery of Dr. Zoghbi and her coworkers is a definite turn...amage tothe brain and nervous system.) The discovery also sheds light on why only females are affected by thesyndrome: because they have only one X chrom...

Normal cellular enzyme becomes marker for Alzheimer's disease

...(in Bothell,Washington). Dr. Kuret made the recent discovery while investigating the workings andwhereabouts of... disease. Yet researchers in the field welcome the discovery of CK-1 and otheridentifiable disease-specific features, called "biomarkers," that can serve assenti...

Researchers discover potential new approach to treating cystic fibrosis

...neand protein therapies and antibiotic drugs. The discovery reported by Alvarezand Freedman points toward a ne...ve officer of the Cystic FibrosisFoundation. "The discovery also illustrates a true partnership in action--asindustry, academia and a private non-profit health ...

Scientist show how viruses co-opt cell defenses to cause chronic infections likethose from HIV and Hepatitis B and C

...nce of co-evolution for the virus and itshost. The discovery could lead to methods to find new antiviral agents, to boost theeffectiveness of antiviral drugs - and possibly to end Hepatitis C and otherpersistent viral infections. Most viral infections begin with a virulent phase straight out of sciencefiction...

Use it or lose it applies to nervous system, scientists find

... to the reversescenario, long-term depression, the discovery that receptors can scurry in andout of synapses st...n theaccessible neuromuscular synapse." The team's discovery also may explain why about 5 percent of patients whoreceive neuromuscular blocking agents while on r...

Memorizing in your sleep

...ion of zif-268 can alter nerve cell behavior, this discovery offers anintriguing glimpse of how the sleeping brain could consolidate recently formedmemories. In rats, certain brain cells that activate during daytime exploration tend toreactivate during sleep. Scientists speculate the sleeping brain reenactswa...

UI study shows classification system for evaluating childhood hip disease may be unreliable

...ature." Based on Weinstein's observation and the discovery that there was little published work concerning the reliability of the Stulberg system, a UI investigative team set out to measure how well surgeons agree with themselves and how well they agree with each other when using the system. The UI investiga...

Studies of growth hormone result in new class of drugs

...cer and other health problems have resulted in the discovery of protein antagonists that have been used to deve...ment of a human disorder. We are very proud of our discovery of this new class of drugs," said John Kopchick, Goll-Ohio Eminent Scholar and professor of molecula...

Estrogen-driven gene activates human pituitary tumors, Cedars-Sinai Medical Center researchers find

...function. This finding builds on the landmark 1997 discovery in Dr. Melmed's laboratory of the oncogene PTTG1 (...tors. Awaiting publication is an important related discovery that PTTG is expressed in other forms of cancer, and that estrogen is linked to its insidious trigge...

Vitamin A compound may help protect younger women against breast and ovarian cancers

...rian Hospital, called the findings "a breakthrough discovery which holds great promise for prevention of breast cancer in younger women. This will stimulate further research into identifying new agents free of side effects which may be used in combination to maximize risk reduction." Importantly, the study al...

Colorado State receives $6.25 million from National Institutes of Health to discover and test new drugs against tuberculosis

...ceutical manufacturer SmithKline Beecham. His drug discovery program will fund two postdoctoral students to wor...uberculosis. Research lab work related to the drug discovery program includes a study of how simple sugars are synthesized in TB cell walls, conducted by profess...

U.S., British scientific societies honor penicillin as International Chemical Landmark

...n. The designation takes place 70 years after the discovery of the drug was first published by Alexander Flemi...e sector research teams that helped move Fleming's discovery from the lab to the hospital will be reunited in London for the designation of the landmark by the R...

Scientific societies honor creation of the Mexican steroid hormone industry

...grew out of American-born chemist Russell Marker's discovery of a way to mass-produce the hormone progesterone. Marker co-founded the Syntex, S.A. drug company in Mexico City, which produced steroid hormones. Marker's work later led to the wide availability of oral contraceptives and cortisone, a treatment f...

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