Duke researchers identify age at onset genes for Alzheimer's and Parkinson's disease
... in some cases the same gene controls onset in two distinct neurodegenerative disorders that share some common features: Alzheimer's disease and Parkinson's disease. We found evidence supporting this hypothesis on chromosome 10," Pericak-Vance said. Researchers also found evidence for age at onset linkage to ...Training can improve age-related memory decline in elderly
...colleagues report that elderly subjects showed two distinct kinds of cognitive-processing deficits -- called "under-recruitment" and "non-selective recruitment"-- when asked to perform memory tasks. Buckner will also discuss the new studies in a press conference at the American Association for the Advancement...Computer-assisted detection of proteomic pattern could help screening for ovarian cancer
...d 50 women without disease enabled the creation of distinct proteomic patterns that distinguished cancer from non-cancer. The discovered pattern was then used to classify an independent set of 116 masked blood samples: 50 from women with ovarian cancer, and 66 from unaffected women or those with non-malignant...Elderly lung cancer patients tolerate aggressive chemotherapy as well as younger patients
...of cisplatin and randomly assigned to one of three distinct chemotherapy regimens, etoposide, high dose paclitaxel or low dose paclitaxel. When comparing results of older patients to younger patients, the researchers found no difference in the response rate to the drugs and the median and overall survival ra...Gene discovery shows heart failure cause, suggests treatments and screening potential
...versity of Utah, identified three patients who had distinct defects in the same gene. The work builds upon research first reported by Mayo Clinic in the early 1990s that showed at least 20 to 30 percent of DCM cases spring from an abnormal gene. While eight other genes associated with DCM have been identified...Study suggests mechanical forces drive early heart development
...opment, we have to look at bending and rotation as distinct components." Taber discussed his theory, experiments and future direction of cardiac biomechanics in "Biomechancis of Cardiovascular Development," in the 2001 edition of Annual Revue of Biomedical Engineering. His work is supported by the National I...Material could lead to self-healing cavities
...t to prevent demineralization, we believe can be a distinct advantage." Dr. Gary Schumacher, a dentist and research colleague of Antonucci and Skrtic, agrees. "I think traditionally one of the biggest problems that the orthodontic patient has is keeping their teeth clean. The brackets, attached to teeth to ...UCSF begins clinical trials for new bionic ear for profoundly deaf adults
...ng nerve at a million times each second through 31 distinct stimulation audio channels. "The new equipment leads to better comprehension of speech because of the processing strategy of the cochlear implant," Lalwani said. The new research options provided by use of the Clarion CII Bionic Ear will foster th...Study points to potential role for caffeine in reducing the risk of Parkinsons disease
...s, which bind the molecule adenosine, are found in distinct areas of the brain, and their expression is restri...ry in Parkinson's disease. "The A2A receptor has a distinct advantage when it comes to treatment because it exists for the most part where you want to target yo...Researchers build on discovery of potent potential antibiotic
...rnal of Molecular Evolution last month, showed two distinct classes of KDO 8-P synthase. In experiments on eight KDO 8-P synthases, another student, David Howe, confirmed that they do indeed fall into two classes---one that requires a metal and one that does not. To determine whether these enzymes, like th...Novartis receives FDA approval for Starlix, a new treatment for type 2 diabetes
... (amino-acid) derivative, has a chemical structure distinct from other oral antidiabetics. Its approval as monotherapy or in combination with metformin was based on data from clinical trials involving more than 3,100 patients with type 2 diabetes. Studies show that Starlix has a "fast on, fast off" mode of ......T cell responses to melanoma, a goal that is quite distinct from the goal of inducing antibody responses as tested in E1694. In 1994 when the currently reported trial was designed, GMK was the most promising vaccine the ECOG Melanoma Committee evaluated, according to Dr. Kirkwood, and the data that support i...Why does an anti-depressant work for some people, but not others?
...es in depression. "Now that we have identified a distinct chain of events in the brains of people who respond well to a specific anti-depressant, we can start to investigate if the same is true for other anti-depressant medications as well as non-drug therapies. We can also use this knowledge as a basis for...Environment contributes to drug tolerance
... in one context and later in another different and distinct context, then the effects of the drug are different," Cepeda-Benito says. "The drug has a much greater effect in a novel context rather than in a context that is associated with the administered drug." Cepeda-Benito, who has studied morphine and nico...Lawrence Livermore Lab pioneers advanced radiation treatment for cancer
...culations for each patient, based on each patients distinct anatomy and disease. Researchers at the University of California, San Francisco worked closely with Livermore scientists during development and validation of Peregrine. "Our collaboration convinced us that this program will be able to accurately pred...Award-winning book looks at responsibility for sick babies in hospitals
...tructure of the health care system gives parents a distinct advantage in how they will be judged as parents -- ultimately affecting how they accept responsibility. But any parent with a critically ill child faces a tough journey in negotiating sometimes life-and-death matters with a rotating host of professi...Kidney transplant proposal reduces wait from 24 to 14 months, improves equity for blacks & women
...ed. UNOS coordinates the activities of 72 OPO's in distinct geographical regions around the country. The authors constructed the large-scale simulation model using data from over 30,000 transplants. The data used for the analysis was extracted from the UNOS Public-Use Data Set, published in 1995.......ry 300-600 years. However, his study also shows a distinct millennial variability, and the frequency and intensity of storms could greatly increase in the next 1,000 years. -- Kam-biu Liu, professor, LSU Department of Geography and Anthropology, 225-388-6136, kliu1@lsu.edu . Hurricane Studies Lead Re...Employers are primary source of health plan information
...red health care coverage through contracts with 15 distinct health-care provider systems in the Twin Cities metropolitan area. "The study results tell us that BHCAG workers rely on their employers for information about health plans," said lead author Roger Feldman, PhD, of the University of Minnesota Di......st as chronic disease control has developed into a distinct discipline in public health, so chronic disease management is now beginning to develop its own identity as an important component of health care," said BMJ 's North American Editor, Ronald Davis, M.D. Edward Wagner, M.D., Director of the W.A. MacCo...