Researchers identify a key 'brake' of the immune response
...transplants to prevent the host from rejecting the donor tissue. On the other hand, doctors would like to b...could create tolerance to foreign tissues, such as donor tissue or bone marrow. Their results also suggest that somehow decreasing the amount of ILT3 and ILT......on-cancer patient receiving a kidney from a living donor as a means to induce drug-free tolerance of the tr...four-hour outpatient session this past month. Both donor and recipient were discharged five days after transplant. "So far, we are pleased with how the donor...JDRF launches multimillion-dollar Center for Islet Transplantation at Emory University
...t issue facing islet transplantation: rejection of donor islets by the patients immune system. Although islet transplantation from donor pancreases can restore normal insulin production in people with Type 1 diabetes, several problems st...University of Pittsburgh transplant researchers present findings at international meeting
...used to provide support to a failing heart until a donor organ is available. But increasingly, transplant teams have seen their patients regaining heart function while on the devices, pointing to the possibility that VADs are a potential treatment for heart failure. But just how does one tell that a patien...Retinal cell implantation shows promise and improvement in advanced Parkinsons disease patients
...lions of cells were grown in cell culture from the donor cells, and they were attached to tiny gelatin beads (or microcarriers) prior to implantation. Surgeons then implanted approximately 325,000 cells in each participant during MRI-guided stereotaxic surgery. The cells were implanted in five different ...Stanford team prevents kidney transplant rejection without drugs
...order to prevent rejection. As an added bonus, the donor kidneys don't even need to come from a relative - ...eam then injected blood stem cells from the kidney donor into the recipient. The stem cells made their way to the recipient's bone marrow where they produced...Stanford researcher dusts off old drug; uncovers new anti-rejection properties
...mune system," Morris said. "Maybe it also acted on donor blood vessels." These results inspired Morris and postdoctoral fellow Camille Dambrin, MD, to test sirolimus on transplanted aortas - the major artery leaving the heart. In their initial trials on rats and primates, delayed treatment with siro...Matching for liver transplants could prevent disease recurrence, says Pitt study
...e than 3,000 transplants suggests such testing for donor and recipient compatibility could reduce the incid...em compatibility, or histocompatibility, between a donor and recipient not only has an impact on the incidence of rejection and graft failure, but disease re...Heartburn surgery helps lung transplant patients
...the transplanted lungs to slough off, causing more donor materials to be presented to the immune system, causing inflammation. "A more intriguing explanation revolves not so much on how the immune system responds to the transplanted organ itself, but how it responds to some other event," Davis said. "If s...Some patients are candidates for combined heart bypass, lung transplant surgeries
...hile the patient was being prepared to receive the donor organ, which was en route to the hospital. The re...didates. "Since there is such a limited supply of donor organs, we have an ethical obligation to make sure that when an organ becomes available, it has a hi...U-M study finds new target in war against graft-versus-host disease
...-effects for more than 5,000 Americans who receive donor bone marrow transplants annually, primarily to tre...lowing a bone marrow transplant from an allogeneic donor someone other than the patient or the patients identical twin. Symptoms of acute GVHD usually begin...New gene therapy protocol: First successful treatment for 'bubble babies'
...products, especially when patients have no matched donor available for safe bone marrow transplantation," Slavin said. Conventionally, such patients are usually treated with ADA replacement therapy in an attempt to rescue the immune system. This replacement therapy, however, is not a long-term solution; i...World's first study on surrogacy reveals high quality parenting and no problems
...ng mother. This was closely comparable to the egg donor families. Ms MacCallum and her team que...athering qualities) the surrogacy families and egg donor families rated higher than families where the child was naturally conceived. For the fifth aspect, ...World-first study shows solo mothers choose donor insemination because they lack a partner
...hirds of single women who choose to have a baby by donor insemination (DI) do so because they feel that the...s about how much information they wanted about the donor they favoured limited non-identifying information. Dr Murray said: "This was the case even among t...Post-transplant nerve regrowth better with young hearts, quick surgery
...antation. Recipients ranged in age from 23 to 60; donor age ranged from 13 to 59. Duration of surgery (measured by the amount of time the recipients' aorta was clamped) varied from about a half hour to nearly 3 hours. In 52 patients, researchers found partial reinnervation, while 25 patients had no evid...... nerve regeneration involves taking a nerve from a donor site on the injured person's body and sewing the donor nerve in between the two ends of the injured nerve. Though the nerve is dead, it provides a pathway ...Panel advises easing selection criteria to boost supply of donor hearts
...available. Only about 39 percent of the potential donor hearts are transplanted. "Implementing these new...iteria "since we suspected that a number of viable donor hearts were not being used." Age is often a factor in selecting hearts. Many centers automatical...Too many lungs rejected for transplantation, study shows
...e than doubling the number of potentially suitable donor lungs. Currently more than 85 percent of lungs are...are is lead author of the paper. "If twice as many donor lungs are truly suitable for transplants, we could save an additional thousand lives a year in the U...Are too many lungs not being considered for transplantation? (p 621)
...considered, including microbiological and non-lung donor factors, approximately 40% of pairs of rejected lungs might have been potentially suitable for transplantation--which could have potentially resulted in a marked increase in the number of lungs that could have been used for lung transplantation. Lorr...International Congress of the Transplantation Society beginning Sunday
...'s kidney transplants are performed, the cadaveric donor rate for 2001 was 4.4 per million population. Braz...efully, this congress will have some impact on the donor shortage crisis, not only through the exchange of ideas on how to best improve organ donation, but b...