Less invasive kidney transplant technique spurring donations
...vasive approach to removing a kidney from a living donor is prompting more people to give one of their kidn...Laskow, a living kidney donation recipient and her donor to be available for interviews August 26. Please contact Kristen Walsh John Patella at (732) 937-85...New Mayo Clinic approach to kidney transplants means more patients can be successfully transplanted
...undergo regular dialysis and wait for a compatible donor organ that their antibodies won't attack. "Sadly, ...ephrologist on the Mayo Clinic team. "As soon as a donor kidney becomes available, this subset of patients usually turns out to have antibodies against it, s...Study shows no deaths from living liver donors in Japan
...ure, but until such time, careful selection of the donor and keeping in mind that donor safety over-rides benefit for the recipient has to be the "credo" of the transplant team."...Safely achieving tolerance to stem cell transplantation
... side-effects and may not necessarily require that donor blood, bone marrow or whole organs are a "match" w...onal antibody administration to achieve functional donor and recipient HSC populations within the donor without the need for myeloablation or stimulating the...University of Pittsburgh receives two grants to try to increase organ donation/procurement
...es effective, the team anticipates more organs per donor will be deemed viable for donation and transplanta... donors, helping to expand the overall size of the donor pool. The study also may help to identify the real and perceived obstacles to increasing the number...Afghanistan's health challenge
...in Afghanistan. A Ministry of Health campaign with donor technical support and funding visited mosques in 2002 and vaccinated 11 million children between the ages of 6 months and 12 years. 94% coverage was achieved nationally and epidemic transmission has stopped.' Afghanistan's example is viewed by The La...Should living liver donation be available in the NHS?
...re likely to die or deteriorate before a cadaveric donor becomes available. It involves a minimum graft to donor weight ratio of 1% and the donor's liver usually regenerates completely in about 12 months. It is cu...Researchers now on road to isolating skin stem cells
...from either the patient before treatment or from a donor are transplanted into the patient following treatm...s in blood. Researchers placed skin cells from two donor mice onto a patch of denuded skin of a third mouse. The cells from one donor were labeled with green...Antigen targeted in therapy for melanoma also prompts immune response in brain tumor cells
...ing blood cells and dendritic cells from a healthy donor and specially prepared TRP-2-positive glioma cells. The immune cells were able to recognize the TRP-2 positive GBM tumor cell lines, and an increase in TRP-2-specific antigen-killing activity could be seen. The identification of TRP-2 as a brain tumo...Improved procurement could more than double availability of life-saving transplant organs
...ecently completed a study that estimated the organ donor potential in the United States and that evaluated the performance of the nation's Organ Procurement Organizations. Dr. Guadagnoli has served on review panels for the National Institutes of Health and the Agency for Healthcare Research and Quality (AH...Non-human molecule is absorbed by eating red meat according to study by UCSD researchers
...han tripled, with little increase in the number of donor organs. This has led to an exploration of using a...ransplantation," Varki said. "However, the leading donor candidate is the pig, an animal in which Neu5Gc happens to be very common. The current study raises...Molecule expressed early in pregnancy may help patients tolerate transplants
...ood antigen matches are desirable between an organ donor and transplant recipient because it reduces the ri... to use HLA-G to modify the dendritic cells of the donor animal then inject them into the recipient rat before Dr. Grandas does the transplant. Aware that t...Study finds way to dramatically increase hematopoietic stem cells
...and examination of their marrow confirmed that the donor tissue had proliferated. "Treatment with PTH had a remarkable effect on these animals' recovery from bone marrow transplantation," says Scadden, an associate professor of Medicine at Harvard Medical School. "This work opens a new angle from which w...New guidelines on unrelated marrow transplants: A roadmap for physicians
... encourage transplant physicians to develop robust donor search strategies, have been issued by the Nationa...of the patient are not available and an unrelated donor is the only hope. The major criteria for marrow donor matching is a set of genetically determined ...Modified lung donor standards decrease mortality
...ate potential lung donors combined with aggressive donor management significantly increases the availabilit...e evaluation and management of every possible lung donor using more liberal or "extended" donor criteria and intensive education of pulmonologists and staff ...Tissue-engineered valves give diseased hearts new life
... overcomes many of the problems with mechanical or donor valves because it is a living structure from the p...ically replacing the patient's aortic valve with a donor valve, a mechanical valve or the patient's pulmonary valve. The pulmonary valve is between the righ...Regeneration of insulin-producing islets may lead to diabetes cure
...stargeted cells. Then they injected the mice with donor spleen cells from nondiabetic mice. A protein com...asis of the animals' diabetes, with transplants of donor islet cells. However, they were surprised to find that most of the mice did not subsequently need th......ne on the transplant waiting list, much as a blood donor gives to anyone in need of a blood transfusion. Th...ransplant centers began responding to non-directed donor requests by developing a policy of evaluation and allocation. Interested donors undergo a substantia...Debate on payments to potential kidney donors: Yes or no?
...to search for new options to increase the stagnant donor pool is prompting a lively debate on the medical a...s. Some argue that paid donations would expand the donor pool and benefit both donor and recipient, while others emphasize ethical concerns involved in payme...Key feature of HeartMate II heart assist device developed at University of Pittsburgh
...harge a patient still on a device to await a human donor outside the hospital. Based on UPMC's experience, the U.S. Food and Drug Administration later allowed patients implanted with the Novacor to be discharged to their home to await heart transplant....