Patients who receive kidneys from older donors do well
.... Patients were divided into four groups based on donor status (living or deceased) and donor age (54 years or younger, or 55 years and older). The researchers found that recipients of kidneys f...Improving the chances of successful organ transplants
...rgan donors and differences in tissue type between donor and recipient that can cause rejection of the donor organ by the recipient's immune system. If this rejection reaction is not successfully treated throu...Donor livers not consistently allocated according to medical need
A new study suggests that donor livers are not always distributed according to a patient's need, but may be retained by some organ procurement organizations with smaller waiting lists and transplanted into less sick patients, according to a study in the April 21 issue of The Journa...Would it be worth it to pay for donated kidneys?
...onors actually donate, but even if every potential donor came through, many on the waiting list still would...ors. Their study shows that society could pay each donor $90,000 and easily break even. "It's a large number," Schnitzler says. "Society saves money, and th...Newborn testing for immune disorders could save lives
...ID patients via stem cell transplants derived from donor bone marrow, typically from a parent or matched si...row is processed to remove T cells, preventing the donor T cells from attacking the recipient, known as graft-versus-host disease. Mature, donor-derived, T c...Major study: Bioartificial liver reduces mortality by 44 percent in acute liver-failure patients
...gh that the liver might recover spontaneously or a donor organ will become available for transplantation. Acute liver failure is diagnosed when a massive loss of hepatic cells causes severe liver dysfunction and life-threatening complications within six months of the onset of symptoms. When this dysfuncti...Insights from intravascular ultrasound explore treatment benefits
...urthermore, 0.3mm MIT is sometimes observed in the donor heart early after transplantation." The value of IVUS end-points as a valid surrogate in the context of a therapeutic intervention was also debated. While most panel members agreed that discrepancies exist in the data to date, clinical decisions can...Using smaller hearts could increase donor pool
The donor heart pool could be expanded by including undersiz... adaptability of undersized hearts to normal-sized donor hearts in heart transplant recipients over a 10-year period and found no significant differences. ...First randomized trial of adult stem cell injections in heart failure patients shows benefit
...being implanted with heart assist devices. When a donor heart becomes available for transplantation, the native heart will be removed, allowing the rare opportunity to look at the heart in its entirety and to more closely examine the effects of the stem cells. "These results encourage us to aggressively...Bone implants could aid healing after tooth removal
...risk of tissue rejection and disease transfer from donor grafts, and it requires no additional surgery to harvest grafts from the patient. "The development of a method for healing critical-size defects in the bone of the jaw would benefit not only those who have teeth pulled but also accident victims wh...Early signs that adult bone-marrow stem cells could regenerate brain tissue
...help treat leukaemia. The investigators found that donor cells containing a Y chromosome (ie, from a male origin) were present in all three women's brains up to 6 years after bone-marrow transplantation. All recipients had transgender brain tissue, and in the longest survivor three different types of brain...Preimplant test offers option of having child to serve as stem cell donor to sibling in need
...the ensuing offspring could potentially serve as a donor to the affected child, according to a study in the...h to have another child as a potential HLA-matched donor of stem cells for transplantation to the affected sibling," the authors write. "In addition to spora...Cord blood stem cells save children with Hurler's syndrome
...28 to 37 percent of Hurler's patients, meaning the donor bone marrow does not take hold and begin to grow in the patient. As an alternative treatment, Duke physician Joanne Kurtzberg, M.D., director of the Pediatric Blood and Marrow Transplant Program at Duke and senior author of the paper, tested the abil...$5 million NIH contract to fund development of pediatric heart assist device
...ast six months until the heart recovers or until a donor heart can be found. Challenges with this type of device include developing very smooth materials and making seamless connections between parts to ensure red blood cells and platelets will not collect in crevices and seams where clots can form, break...University of Pittsburgh approach has lung recipients taking far fewer drugs
...a day, a regimen that is intended to safeguard the donor organ from immune system attack. But rejection pla...y immune system cells that are known to target the donor organ that is given just before transplantation. Following transplantation, patients are treated wi...Cedars-Sinai Medical tipsheet for May 2004
...olong life while an injured liver recuperates or a donor organ becomes available for transplantation. Study results are published in the May issue of Annals of Surgery. MEMORIES OF PATIENTS' GRATITUDE ARE PROMINENT AS CEDARS-SINAI STAFF MEMBERS READY FOR MEDICAL MISSION TO GUATEMALA IN MAY For Dr. Alan ...CellCept(R) registry data demonstrated superior long-term organ transplant outcomes
...ceive transplants from either a living or deceased donor every day and over 25,500 transplants are performed each year. Currently, there are more than 84,000 people on the nation's organ transplant waiting list. "Over the past decade, CellCept has helped to improve the lives of thousands of kidney, liver ...Matching method helps doctors successfully transplant higher-risk kidneys
...ists regarding the optimal approach to the elderly donor or recipient," said Stratta. In a separate study of 129 transplant patients who received kidneys from deceased donors, Stratta and colleagues compared 96 patients ages 19 to 59 to 33 transplant patients who were 60 years of age and older. "An avera...New class of compounds promises to revive failing hearts
...e effects of nitroxyl have used Angeli's salt as a donor of that substance, prompting Toscano's team to set to work to develop new sources. New nitroxyl donors not only would confirm that the physiological effects seen with Angeli's salt are truly due to HNO, but they also would help researchers determine ......gineering has many advantages, including a smaller donor site that heals faster and a graft that is mucosal cells, more like the mouth lining, not skin. After a short healing period, the patient feels mouth lining as it is supposed to feel. In their research, Feinberg and Izumi took thin pieces of mu...