Tag: "dopamine" at medical news

Brain activity, including memory-processing, changes in Tourette syndrome

...bnormal activity involving a brain chemical called dopamine is somehow connected to the movements and vocaliza...the drug levodopa, which is used to treat abnormal dopamine activity in conditions such as Parkinson's disease, normalized brain activity during the memory task...

Mind-body connection in placebo surgery trial studied by University of Denver researcher

...ffectiveness of transplantation of human embryonic dopamine neurons into the brains of persons with advanced Parkinson's disease. Twenty patients received the transplant while 20 more were randomly assigned to a sham surgery condition. Dr. McRae reports that the "placebo effect" was strong among the 30...

Exposure to food increases brain metabolism

...ally, to better understand the relationship of the dopamine system to obesity, they looked at the brain circui...at, like drug addicts, these individuals had fewer dopamine receptors than normal control subjects ( http://www.bnl.gov/bnlweb/pubaf/pr/2001/bnlpr020101.htm ). ...

Molecule pumped directly into brain improves Parkinson's disease symptoms

..., 2004. The cause of Parkinson's disease (PD) is a dopamine deficiency in the brain. Dopamine is a neurotransm...ervous system. In PD the neural cells that produce dopamine deteriorate, and the normal rate of dopamine production decreases. In this study, researchers examin...

Study shows possible link between Parkinson's medication and cardiac valve disease

...uld be given to switching patients to an alternate dopamine agonist," concludes Dewey....

Medication for multiple sclerosis may help in treating cocaine addiction

...rug abuse counseling and a medication that targets dopamine release in the brain may offer hope to the many people struggling with cocaine dependence. There are currently no Food and Drug Administration-approved medications to treat cocaine addiction. Dr. Steven Shoptaw and his colleagues at the University of...

Highlights summarized for movement disorders research at 56th annual meeting

...D therapy, but must be converted in the brain into dopamine by an enzyme called AADC (aromatic L-amino acid de...reviously unrecognized side effect. Pergolide is a dopamine agonist, a drug that acts like dopamine in the brain. Researchers from Texas presented evidence that...

One-drug therapy approach to treating bipolar disorder

...however we know the drug impacts neurotransmitters dopamine and serotonin. The most common side effect is fatigue, so it may not be the best initial approach in patients who experience significant lethargy as a symptom of depression." The trial tested two dose levels of Seroquel (quetiapine fumarate), 300...

It's a gamble: Dopamine levels tied to uncertainty of rewards

...ew combination of techniques, have discovered that dopamine levels in our brains vary the most in situations w...s, we were actually able to measure release of the dopamine neurotransmitter under natural conditions using monetary reward," said David Zald, assistant profess...

New compound may act to keep thyroid activity in check

...uickly, and it has a chemical structure similar to dopamine or serotonin. Since it looks like a neurotransmitter and acts like a neurotransmitter, we hypothesize that it is a neurotransmitter." Scanlan, an expert on thyroid hormone chemistry and pharmacology, synthesized T1 amine. The researchers at OHSU and ...

Yerkes researchers discover combination of drug therapies reduces cocaine use in primates

...researchers observed the innovative combination of dopamine transporter (DAT) inhibition and serotonin transporter (SERT) inhibition was effective in limiting cocaine use in rhesus macaques who are trained to self-administer cocaine. "It appears DAT inhibition serves to substitute for cocaine, while SERT inhi...

News tips from the Journal of Neuroscience

...ery resulted in a faster onset and larger block of dopamine reuptake. Such kinetic data may also be important in designing anti-addictive treatments strategies. 2. Sizing up autism in the amygdala and hippocampus: The amygdala is enlarged in children, but not adolescents, with autism; the hippocampus is en...

GSK'S Requip(R) (ropinirole HCl) significantly reduces periodic leg movements in patients with RLS

...t). About Requip Requip is a second-generation dopamine agonist that directly stimulates post-synaptic dopamine receptors in the brain. It is believed that RLS may be caused by a dopamine dysfunction. Requip ...

Topiramate: a potential new medication for treating alcoholism

...ntemporaneously on more than one neuromodulator of dopamine function. Results indicate that topiramate can re... craving. Whereas alcohol consumption facilitates dopamine neurotransmission, topiramate a sulfamate fructo-pyranose derivative decreases dopamine release th...

Lab studies show two proteins prevented progressive nerve cell loss in Parkinson's disease

... "substantia nigra" that produce a chemical called dopamine begin to malfunction and progressively die. Dopami...on. But as more of these cells die, less and less dopamine is produced, causing Parkinson's disease. To treat the symptoms of Parkinson's disease, doctors rel...

Northwestern receives $2.1 million grant for Parkinson's disease research

...rant will fund research aimed at understanding why dopamine neurons die and how the brain adapts to the death ...s disease, levodopa therapy, is aimed at restoring dopamine levels by enhancing release of the neurotransmitter from surviving dopaminergic neurons. Although in...

Researchers monitor progression of Parkinson's disease by studying molecular changes in brain

...n computed tomography (SPECT) to image the loss of dopamine transporter binding.(While the pathology of Parkin...he disease's progression is marked by a decline in dopamine transporter binding, part of the brain's neurotransmitter circulation system.) The study demonst...

Promise of stem cells amplified

...use the neurotransmitter dopamine. "Replacement of dopamine neurons using embryonic stem cells has long been t...ic muscle movements." So instead of replacing the dopamine cells, she and her colleagues found a way to provide support to neurons under attack. Dopamine neuro...

Advances in understanding brain circuits responsible for tics in Tourette's shed light on disorder

... usually peak in early adolescence." Knowing that dopamine antagonist drugs reduce the tics associated with T...at the ventral striatum--a brain region where both dopamine and serotonin have important functions--could be involved in Tourette's syndrome. Noninvasive imagi...

Exercising limbs protects brain cells affected by Parkinson's, study in rodents shows

... of axon terminals in the striatum, the site where dopamine is usually released. When delivered to one side o...ata suggest the possibility that exercise can make dopamine neurons resistant to neurotoxins and may therefore be a useful therapy for Parkinson's disease," not...

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