Duke Study Uses Tiny Temperature Changes To Probe Water-Exclusion At Protein Binding Sites
...moving this water provides much of the energy that drives a bindingreaction, and determining how much energy...eryact of leaving the protein binding sites, water drives the binding of aligand to a much greater extent than was previously imagined. The bindingsite become......itor. Duerks group has rewritten the software that drives the machine so it can make images more rapidly. As a result, the image acquisition rate has risen from one frame every two minutes to one per second. The addition of a three-camera array allows doctors to follow the precise position of the r......R-ABLprotein increases the enzymatic activity that drives the white cells toproliferate uncontrollably, inducing leukemia. Essentially, there are no brakesto stop the proliferation. The investigational drug inhibits the enzymatic activity of the renegadeBCR-ABL protein. Called a tyrosine kinase inhi......orks and why it malfunctions remains amystery that drives scientists and physicians to seek answers. A scientifictriumph in this crusade occurred when an advanced brain imaging agent, calledTrodat, was developed at the University of Pennsylvania Medical Center. Thisimaging agent could be a key to the unde...Breakthrough? Study Finds Dopamine Cannot Be Source Of Pleasure In Brain
..." he said. "Often it is new technologythat in fact drives new findings in science and medicine." The National Institute of Drug Abuse and the National Institute ofNeurological Disorders and Stroke supported the continuing studies. A feature onthe work in Wightman's laboratory will appear in April in...'Motion Blindness,' Not Just Poor Memory, Causes Alzheimer's Patients To Lose Their Way
...s,like snowflakes rushing at the windshield as one drives through astorm, that our brains use to understand how we're moving. In acar, the way the flakes part helps most individuals realizethey're moving forward; Alzheimer's patients would see the flakesmove, but they have a much harder time understanding w...Researchers discover the driving force behind cancer cells in Hodgkin's disease
...r the first time we have identified theengine that drives at least some Hodgkin's cancer cells to multiply. We are nowworking to find a way to shut down that engine. These findings have hugeclinical potential," said Dr. Tak W. Mak, senior scientist at the Ontario CancerInstitute, director of the Amgen Res...Obesity drugs not a quick fix for achieving weight loss
...ional social pressure to lose weight. Thispressure drives many patients to look to drugs as a possible quick...vator to the snack machine a fewtimes each day and drives to the pizza place or hamburger joint for dinner andmaybe a few beers is a good candidate for weight...New model suggests that AIDS drugs may not abolish HIV infection
...during treatment. Rather,antiretroviral treatment drives HIV down to stable levels, which vary with theefficacy of the drug regimen. One implication of the new model could be a morefavorable interpretation of some treatment outcomes once described as failures,according to a report in the October issue of ...Northwestern chemist develops nanoplotter with parallel writing capabilities
...unicate with the customized computer software that drives the nanoplotter. In the case of the eight-pen nanoplotter, the other seven writing tips are passive and follow the lead of the pen with the imaging tip, drawing identical patterns a fixed distance apart. Mirkin and Hong demonstrated the nanoplotter...... and water. This reaction releases the energy that drives the engine. Air, the engine's source of oxygen, does not contain enough oxygen to react fully with gasoline, so some hydrocarbons remain unburned. The energy thus lost could be used to power the engine more efficiently, according to Waters. Unburn...Story tips from the Department of Energy's Oak Ridge National Laboratory, October 2000
...hera force that overcomes the Coulomb force, which drives the like-charged protons apart, similar to the like poles on two magnets. [Contact: Jim Beene]...Alcohol and drug treatment among HMO patients
...poverty, it is assumed that it is the poverty that drives the difference between Caucasians' and African-Americans' substance use problems. This study shows that this explanation is probably not true, because almost everyone in the sample was a middle-class person. Even within the middle class, we can see...Drug war strategy: First fund enforcement then switch to treatment, says O.R. paper
...s a result, the costs of distributing drugs, which drives up the price. Initiation, Cessation and Use: The authors' model reflects how driving up price both reduces the number of users (by moderating initiation and spurring cessation) and rates of consumption for those who continue to use. Treatment: The ...Study on teen licensing: N.C. crashes involving 16-year-olds drop dramatically
... include at least six months during which the teen drives extensively with a responsible adult supervisor, followed by prohibitions on unsupervised nighttime driving and transporting of passengers, until the teen has accumulated at least six months of additional driving experience without an adult superviso...UF study: Grandparents celebrated instead of reviled in children's lit
...via hates to be called Granny or anything like it, drives a Volkswagen Beetle, doesnt sew or cook well and has a rude parrot for a pet, he said. Such portrayals are important because children exposed to this type of literature have a better chance of accepting old age and grandparenting than prior generat...Number of teens --primarily boys -- having sex declined in '90s
...the definition of a relationship has changed. This drives parents crazy because a boyfriend can be like the flavor of the month rather than going with a guy for two years. "A girl today might be called a 'slut' because she had sex outside a relationship, not because of the number of partners she had. Boys...Aspirin's target, the COX-2 enzyme, linked to cancer of the uterus
... depends on estrogen for fuel, and estrogen itself drives the manufacture of prostaglandins. "You see how crafty this cancer is," Bulun said. "By encouraging the production of COX-2, it sets in motion a continuous cycle whereby the tumor can thrive and grow." In two additional articles published in the July...Study finds new target for development of anti-cancer drugs
...e cell. One such motor is called dynein. As dynein drives along microtubules, it carries cargo from the outside of the cell toward the middle, closer to the nucleus. km23 helps to connect the right cargo to the motor so that the cargo can reach the appropriate destination. Mulder and her team also found tha...... hours of resting in a recovery room. Then, Harris drives back home where he putters in the garden and kitchen in between his volunteer work at Duke and his position as medical director at the Wellspring retirement community in Greensboro. Compare this to the months of painstaking recovery that he endured ...