Gene vaccine protects mice against development of Her2/neu breast cancer
... aggressive disease that is difficult to stop. The drug Herceptin treats this kind of breast cancer by "plugging" these receptors with a monoclonal antibody, but this treatment "produces only a passive and transitory immune reaction," Lachman said. "This vaccine, however, like many that treat microbial in...Doctors must consider potentially inappropriate medications when treating elderly
...nts are taking. "Sometimes someone is started on a drug in their 50s, but 20 years later, it has not been ...etimes doctors have tried everything else and this drug with negative implications for the elderly is the only one that works. It is a complicated issue th...New therapeutic vaccine for HIV/AIDS eliminates needles and excessive toxicity
... new option which complements and improves present drug therapies. The vaccine, applied topically to the skin, has demonstrated efficacy in boosting immune responses and controlling virus replication in chronically infected monkeys. This treatment possibly offers a new, non-invasive option for HIV-infec...Mayo Clinic Cancer Center receives SPORE grant for brain cancer research from NCI
... that inhibit invasion. In conjunction with Mayo's drug discovery research efforts, Project 3's researchers have identified a "short list" of small molecules that inhibit this protein. The SPORE grant will facilitate the translation of this discovery into a clinical trial. Project 4 will explore the gene...Antibiotics protect nerves in mice by turning on genes
...rm antibiotic treatment are worth it, he says. The drug is currently approved by the U.S. Food and Drug Ad...nation might offer a real therapy, much like using drug combinations to treat cancer," says Rothstein. "The more we know about ALS and other neurological di...New protein discovered by Hebrew University researchers
...quences for development of future nanocapsules for drug delivery to cancer cells. In addition to being ob... cells. Therefore, the units of SP-1 carrying the drug would invade only the tumor-feeding blood vessels and not normal ones. More recently, the three-d...Study finds herpes virus in 98% of healthy participants
...ufman, who developed the first effective antiviral drug for herpes infections of the eye. In addition to Dr. Kaufman, the research team included Drs. James Hill, Hilary Thompson, Gregory Sloop, as well as Emily Varnell and Ann Azcuy. They concluded that control of virus excretion could well limit transmi...Sex habits of young women unchanged by morning after pill, UCSF study finds
...traception in advance, or were assigned to get the drug by going through a clinic (the study's "control" group). Six states, including California, allow emergency contraception to be dispensed at pharmacies without a prescription in cases where pharmacists have been specially trained and have a collabora...Women need less morphine after hysterectomies with new treatment
...tients were given a combination of an anti-seizure drug called gabapentin and an anti-inflammatory COX-2 inhibitor drug called rofecoxib, in addition to self-administered morphine. The patients were asked to rate their p...Tip sheet Annals of Internal Medicine, Jan. 4, 2005
...ts who monitored the effect of their anticoagulant drug dose achieved similar levels of control over blood clotting as compared to patients who went to a clinic to have blood levels checked (Article, p. 1). Self-management patients also had fewer major complications (including death) and minor hemorrhages...Jefferson virologists coax HIV out of hiding
...a combination of drugs. "We may need more than one drug to stimulate virus from latency, similar to using HAART to stop replication," he says, referring to this approach . "We may have to combine IL-2 with IL-7 and other agents to get to the reservoirs of virus."...Social development program in childhood aids in positive functioning as an adult
... reported greater job stability, less incidence of drug use, and greater overall emotional well being compared with a control group, according to an article in the January issue of The Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals. "The transition to early adulthood is a ...Urinary tract infections likely caused by tainted food
... of the outbreak was probably foodborne. Bacterial drug resistance due to unnecessary antibiotic usage is ...s not much people can do" to combat the increasing drug resistance, he added. Instead, foodborne illnesses are best avoided by smart food preparation. "The ...BMJ turns missing murder case documents over to FDA
The BMJ has turned over confidential drug company documents that went missing from a 10 year...ymous source, appear to suggest a link between the drug fluoxetine (Prozac), made by Eli Lilly, and suicide attempts and violence. They also suggest that El...What is driving the rise in over the counter drugs?
...hers in this week's BMJ? Generally, a prescription drug becomes a candidate for over the counter availabil... recent switches, such as the cholesterol-lowering drug simvastatin in the United Kingdom, do not fit this description. The authors suggest that switches ar...Getting pregnant while on the pill: Yet another health hazard of being overweight
...t. "The more fat a person has, the more likely the drug is sequestered, or trapped, in the fat instead of circulating in the bloodstream," Holt said. Another factor that may account for obesity-related pill failure is that today's oral contraceptives contain relatively low hormone levels compared t...Pegaptanib provides benefit for neovascular age-related macular degeneration
...ye disease. These studies formed the basis for the drug development and clinical trials of anti-VEGF thera...of the disease. Current treatments, which employ a drug and laser, are able to slow vision loss, but have not been widely applicable to all patients. Pegapt...Study explores antibiotic misuse
...de, and take it correctly, meaning keep taking the drug until it is gone, not just until symptoms disappear. But in doctors' offices and hospitals across the country, patients have come to expect antibiotics for viral infections and too many doctors are willing to give them, says Dr. Wilde. "W...LA BioMed Medical/Research briefs January 2005
...y at Harvard University to see whether the illegal drug ecstasy can ease the debilitating anxiety that cancer patients feel as they face their final days. To learn more about the study, see the project web site at www.canceranxietystudy.org . To contact the principal investigator of the study, Cha...Web-based tool to help clinicians make schizophrenia treatment decisions
...s in crises like suicidality, violence, and severe drug side effects," said Meltzer, the Bixler/Johnson/Ma... for these crises before deciding on the course of drug therapy. Also, the algorithms are designed to help clinicians who are not psychiatrists evaluate a p...