NYU'S Duster cautions against FDA approval of 'race-based' pharmaceutical
...k men. NitroMed, which intends to market the drug to African Americans after FDA approval, has noted...s that have the actual functional association with drug responsiveness, thus assuring that the drug be approved for everyone with those markers, regardless ...Genetic amplification (NAAT) test detects HIV more effectively than standard tests in urban study
...rcent more cases of HIV infection in urban STD and drug treatment clinics and HIV testing sites in Atlanta...esistant HIV. Our results show that urban STD and drug clinics and HIV testing sites should consider adopting HIV testing that includes NAAT." ...Study examines harm reduction among injection drug users
Nearly half of injection drug users disposed of their used syringes safely, yet ...om safe sources, according to a study of injection drug users in Baltimore, Md., conducted by researchers at the Johns Hopkins Bloomberg School of Public He...Adverse drug events in nursing homes are far more common than previously identified
Injuries from adverse drug events in the long-term care setting are more comm...ring that time, researchers identified 815 adverse drug events which caused injury to the patient. Of those events, 590 were deemed "less serious", 188 were...Plant derivative attacks the roots of leukemia
...t progressive leukemia treatment, a relatively new drug called Gleevec, is effective only to a degree. It ...cted to parthenolide, versus a common chemotherapy drug called cytarabine. The result: parthenolide selectively killed the leukemia cells while sparing the ...CK2 protein sustains colon cancer cells by sabotaging ability to commit suicide
...fically, when the team added to the cancer cells a drug that blocks caspases, TRAIL-induced apoptosis was also blocked. "Our discovery that blocking CK2 makes cancer cells sensitive to TRAIL-induced cell suicide is very promising," said Kamel Izeradjene, Ph.D., a postdoctoral student in Houghton's lab wh...Potential drug target for treating cocaine abuse found
..., DC February 17, 2005 -- A substance similar to a drug used in the treatment of Parkinson's disease block...f cocaine and could potentially be used to develop drug therapy for cocaine abuse, new research shows. In an article published in the February 23, 2005, iss...Study examines three-day antibiotic regimens for treating bladder infection in women
...itis if the woman has no history of allergy to the drug and if the likelihood of trimethoprim-sulfamethoxazole resistance is low. In areas where the likelihood of trimethoprim-sulfamethoxazole resistance is high (greater than 20 percent) or in women who have risk factors for trimethoprim-sulfamethoxazole ...World's biggest study of multi-million pound health problem launched
...ribe laxatives, which are the 12th most prescribed drug in the UK. Currently, one-fifth of the over-65s use laxatives. Within LIFELAX, the research team, from Newcastle University's Centre for Health Services Research and the Human Nutrition Research Centre, working with doctors from primary and seconda...Investigational transplant drug effectively preserves kidneys while avoiding toxic side effects
... immune signal, Drs. Larsen and Pearson tested the drug in nonhuman primates and found that it significantly prolonged survival of transplanted kidneys. "The studies with nonhuman primates were critical because, while we knew the co-stimulatory blocker was effective in vitro, we needed to study it in a ...Insurance incentives might help smokers quit, study says
...cotine replacement products and the antidepressant drug bupropion can increase the chances that a smoker will give up the habit. But "costs are a significant barrier to the use of smoking-cessation treatment. Healthcare providers may be deterred from offering treatment if they do not receive reimbursement...High-intensity ultrasound creates hollow nanospheres and nanocrystals
...The nanospheres could be used in microelectronics, drug delivery and as catalysts for making environmentally friendly fuels. "We use high-intensity ultrasound to generate nanoparticles of molybdenum disulfide or molybdenum oxide, which bind to the surface of tiny silica spheres that are much smaller than ......d number of health-care facilities can be used for drug distribution (each of them serving the population in a specific area), the researchers determine an optimal equitable allocation strategy. They then apply this approach to a practical example--the equitable allocation of antiretrovirals to patients w...The courage to change the rules: A Proposal for an essential health R&D treaty
...focus directly on R&D rather than patent rights or drug prices, and it would address the global management of publicly funded health R&D. "Priorities for R&D would be defined through public-sector leadership and based on public health needs." Dentico and Ford argue that the World Health Organization, as ...Regular cannabis may increase risk of stroke in young users
... of Neurology Neurosurgery and Psychiatry. Illicit drug use is known to be associated with an increased ri...on. But they conclude: "Cannabis is not as safe a drug as many believeFuture studies will be needed to clarify the role of cannabis as a stroke risk factor...Heart attack treatment gap may be closing for women
...r have chest pain are being prescribed appropriate drug intervention at hospital discharge at the same frequency as men, researchers reported at the Second International Conference on Women, Heart Disease and Stroke. A sub analysis of a National Institute of Health funded study showed that women were jus...The history and controversy behind post-menopausal hormone therapy
...ness point of view, the most reliable profits [for drug companies] can be made from disease processes and ...e authors state. Post-menopausal symptoms provide drug companies such an opportunity, even for those with drugs that create positive results, i.e. prevent ...Study finds new designer drug is potent treatment for chronic myelogenous leukemia
...no longer binds to Gleevec at all. Using rational drug design to circumvent these shortcomings, researche...chool. "This is an elegant example of how rational drug design developing drugs based on a molecular understanding of cell structures and processes can be...Miniaturized lab permits saliva screening on the go
...liva tests are already in use, such as alcohol and drug tests that can be performed on the spot by police, to replicate other tests, such as the presence of anthrax, would require an entire laboratory. Malamud and his colleagues are striving to, in essence, reproduce a laboratory in a small device that c...Vaccine may complement conventional treatment for chronic leukaemia
... division. Patients with CML can be treated with a drug called imatinib or interferon alfa. Treatment with imatinib can lead to complete cytogenetic remission, where no Philadelphia chromosomes are detected during cell division. However, a complete molecular response, where there is no evidence of the pro...