Clot-busting drugs may help detect potentially deadly leg clots
...Robinson. Adding tPA or some other clot-dissolving drug right before the test may clear up those positives and negatives, he says, hypothesizing that measuring the difference between the standard and the new 'provoked' d-dimer test will allow the clinician to better determine whether the clot was present ...Age should not be a factor in determining heart transplantation eligibility, researchers say
...ommon contraindications include a smoking habit, a drug or alcohol addiction, excess weight, or a mental disease, Wang said. However, Wang added that more than half of all institutions that currently offer heart transplants in North America consider age a contraindication and will not perform the surgery ...Mayo Clinic identifies key cellular process in prostate and other cancers
... suggest a promising new treatment target at which drug designers can aim new therapies for prostate cancer, as well as a number of other human cancers in which elevated levels of Skp2 have already been documented. These include cancers of the breast, lymphatic leukemia, small cell lung cancer and certain...Dialogue & personal example work best for parents in drug talks with teens
...an more effectively advise teens about alcohol and drug use if, first, they try dialogue instead of lectur...an everyday example, rather than give the one-time drug sermon, according to a Penn State researcher. Drug talks can work best when parents and teens routi...Penn joins major NCI research initiative to advance breast cancer therapies
...ll it recur? Will it respond to therapy? Will this drug work or should we move on to the next drug?" For e...specific type of stomach cancer who respond to the drug Gleevec show a dramatic change in glucose metabolism within 48 hours of taking the drug. In this way...Over prescribing causing high rates of antibiotic resistance in south and east Europe
... infections, culture and education, differences in drug relations and in the structure of the national pha...on, population densities, the effects of different drug classes, and the differences between bacterial species, it will help us to design and measure the su...Herbal extract as effective as commonly prescribed anti-depressant
...com today. St John's Wort* and the anti-depressant drug Paroxetine** were used in a trial to treat patients with moderate or severe depression. The researchers asked 301 participants of both sexes from German mental health centres to take part in the trial. The two drugs were taken by the patients aged 18...Electronic medical records reduce hours, cut cost
...rtual medical record from health plan claims data, drug claims data and lab test results. The system continually compares this patient data to the latest evidence-based medicine and standards of care, to identify treatment opportunities for those most at risk. These opportunities or suggestions - called...Leukemia drug breakthrough study in New England Journal of Medicine
...y conducted a phase I/II trial of the experimental drug Revlimid showing promise as an innovative way to t... to the U.S. Food and Drug Administration in a new drug application (NDA) for Revlimid as an innovative approach to treat the anemia of MDS patients with th...Physicians call for increased funding for federal infectious disease programs
...rding to the Institute of Medicine (IOM). Although drug resistance is on the rise, very few new antibiotics are being developed. "We must reinvigorate the anti-infectives market so that infectious disease doctors have the drugs we need to take care of our patients," said Dr. Stamm. The HIV/AIDS pandemic c...Mount Sinai stroke prevention trial published in JAMA
... ximelagatran and decreased either with or without drug discontinuation, a few patients developed more severe liver reactions. About Atrial Fibrillation Atrial Fibrillation (AF) is a common irregular heartbeat that occurs when the two small upper chambers of the heart (known as the atria) beat rapidly ...Simpler blood thinning medication effective for preventing blood clots and stroke
... stable pharmacokinetics with little potential for drug interactions, and no known food interactions. This trial, SPORTIF V (Stroke Prevention using an Oral Thrombin Inhibitor in Atrial Fibrillation), was conducted in 2000-2001 at 409 North American sites, involving 3,922 patients with non-valvular atrial...New stroke-prevention drug unlikely to be cost-effective except in patients at high risk of bleeding
..., 2005 --A new study has shown a stroke-prevention drug designed to be an improvement over prior treatment...Medicine in St. Louis found, however, that the new drug would be cost-effective for those atrial fibrillation patients whose risk of bleeding is high. The ...Sex hormone metabolite reduces stress, anxiety in female rats
...the Journal of Neuroscience , could provide a new drug target for treating anxiety and depression in women. In the study, Emory researchers Donna Toufexis, PhD, Michael Davis, PhD and Carrie Davis, BS, and Alexis Hammond, BS, of Spelman College, compared how female rats with different levels of the sex ...Contrary to previous findings, smoking is detrimental to patients with Alzheimer's
...heimer's disease, the researchers administered the drug in the drinking water of 20 mice that were genetically engineered to develop both the plaques and the tangles of Alzheimer's disease. The researchers found that chronic nicotine exposure increased the tangles while having no significant effect on the...Bone density returns when teens stop using Depo Provera, Group Health study finds
...rning on Depo-Provera. The warning states that the drug is associated with bone loss that "may not be comp...ne loss of 0.97 percent, while those not using the drug had an increase in bone density of 1.32 percent. These bone-loss rates are similar to that of women ...Bone density appears to recover after adolescents discontinue injected contraceptive
...rning" for DMPA, stating that prolonged use of the drug may result in significant loss of bone density, that the loss is greater the longer the drug is administered and that bone density loss may not be completely reversible after discontinuation of...Rice's CNST awards Smalley/Curl funds for innovation
...pes to engineer these patchy capsules for targeted drug delivery and other advanced encapsulation applications."I am thrilled to receive this honor in the first year of its inception, and I look forward to carrying out research with my students to achieve the vision set out by Rick Smalley and Bob Curl fo...US FDA grants full approval to DOXIL(R) following submission of phase III data
...In March 2004, J&JPRD submitted a supplemental new drug application (sNDA) based on data from the Phase III study. "The Phase III data provide evidence of the product's clinical benefit for patients with relapsed ovarian cancer," commented Alan N. Gordon, M.D., of the University of Arizona School of Medi...Methamphtetamine's ruinous effects on children documented in Midwest study
...s in a "thunderstorm" of family problems, then the drug methamphetamine brings a "tornado" by comparison, ...hat makes it easier to hide the manufacture of the drug also makes it easier to hide evidence of child abuse and neglect, the researchers noted. They heard ...