Yale opens Center for Interdisciplinary Research on AIDS (CIRA) in India
...tions such as sex workers, truckers, and injection drug users by altering the context within which individuals engage in health behaviors or make healthrelated decisions. The Yale team, led by principal investigator Kim M. Blankenship, CIRA's associate director and associate research scientist in the Depa...Anti-depressants used during pregnancy linked to neonatal withdrawal syndrome
...nd colleagues screened the WHO database of adverse drug reactions for cases of neonatal convulsions and ne...ported only in eight cases, and in all of them the drug was used for 4 to 60 months before delivery and stopped at delivery. Professor Sanz concludes: "Wit...Canadian neurologist wins highest award as American Stroke Association honors five
... major clinical trials resulting in more effective drug treatment of stroke. Marler was project leader f...ular Research efforts that led to approval of the drug tPA as the first treatment for acute stroke. As leader of the NINDS Clinical Trial Group, Marler is...Association publishes blueprint to strengthen stroke care from prevention through recovery
... to the symptoms and damage caused by stroke. The drug tissue plasminogen activator (tPA) is a clot buste...h is caused by blocked arteries in the brain. The drug is approved for use during a three-hour window of symptom onset before brain damage becomes irrevers...Inflammatory cells highly promising target in NF 1
...of this year, and are experimenting with potential drug compounds now. Dr. Clapp, professor of pediatrics and of microbiology and immunology, said one target of their efforts will be mast cells, which are immune system cells that are involved in asthma and allergic reactions. Mast cells play a role in neu...American Thoracic Society Journal news tips for February 2005 (first issue)
...CTS AGAINST ALTITUDE-INDUCED PULMONARY PROBLEMS A drug commonly prescribed for male erectile dysfunction, sildenafil, is capable of protecting men against the development of high altitude-induced pulmonary hypertension, helps to improve pulmonary gas exchange, and limits altitude-induced hypoxemia (defic...Cholesterol under-treated in high-risk women in managed care study
...des. Managing low HDL and high triglycerides with drug therapy in high-risk women was strongly recommended in the new guidelines. Evidence of poor management of these factors provides further evidence for a need to improve comprehensive lipid management in the highest-risk women, Mosca said. "These find...New way to block pox shows promise in lab study
...ons, including smallpox, may be halted by aiming a drug not at the virus but at the cellular machinery it ...oach that might eliminate the problem of antiviral drug resistance, report researchers supported by the National Institute of Allergy and Infectious Disease...Women's heart risk underestimated by doctors, resulting in less preventive care than in men
...recommendations regarding lifestyle management and drug therapy for blood pressure, cholesterol, aspirin a...are. Preventive measures, including lifestyle and drug therapy, have been shown to save lives in both men and women." Furthermore, less than one in five ...Treatment for brain tumor does not always follow recommendations
...delines (e.g., frequent prophylactic antiepileptic drug administration) or may conflict with published literature (e.g., relatively infrequent use of chemotherapy), and still others point out areas for further investigation in this population, including heparin prophylaxis for venous thromboembolism, anti...Other highlights in the February 2 JNCI
...atment with chemotherapy regimens that include the drug cytosine arabinoside, children with Down syndrome ...n syndrome AMkL patients are more sensitive to the drug and respond better than non-Down syndrome AML patients. Contact: Kelly C. Scheer, Public Relations, ...No magic pill for treating dementia symptoms
...ion. "Our review of 29 research studies found that drug therapies are not particularly effective for manag...ouraging to find that we currently don't have good drug therapies for them." More than half of people over age 85 are affected by dementia. Dementia-related...Calcium and vitamin D most effective for treatment of Crohn's-related bone loss
...he University of Alberta, adding the bone-building drug etidronate (Ditronel) to calcium and vitamin D the...at physicians should only consider BMD testing and drug therapy for patients who are at higher risk for osteoporosis and fractures, not those who merely hav...COX-2 inhibitor increases the risk of heart attack in elderly adults with no history of heart attack
...doubles for those who are taking high doses of the drug even when using aspirin." COX-2 inhibitors are commonly used to relieve the pain and inflammation caused by arthritis in the elderly. These drugs are believed to increase the 'stickiness' of blood platelets--the tiny bodies that assist in blood clot ...Drug treatment promising for halting Huntington's-related nerve death
...nd that treatment of the cells in culture with the drug enoxaparin prevented inappropriate calcium release...dition, the researchers would like to expand their drug search beyond molecules that block calcium release and the mitochondrial pore. "We're looking for d...Penn study shows how next-generation diabetic drugs could work more selectively
...e should be optimistic about finding a new type of drug with the same fat-cell target as TZDs, but which is a selective regulator of gene expression in such a way that will increase the benefit-to-risk ratio of the diabetes treatment," says Lazar....Longer cardiac rehab programs necessary, says U of T study
...he remaining 26 weeks. Patients were kept on their drug therapies and had nutritional interventions as well as being prescribed a walking or walk-jog (where appropriate) program. Dr. Larry Hamm, an adjunct professor in U of T's Faculty of Physical Education and Health and program director of cardiac reha...Clinical trial of Etanercept for Wegener's disease shows no benefit
...ed clinical trial. All patients received standard drug therapy to treat the disease. In addition to stan...on between TNF inhibitors and cyclophosphamide - a drug known to cause several types of cancer. This potential association bears further scrutiny," said St...Reviparin effective in reducing risk of death after heart attack
The drug reviparin (a low molecular weight heparin anticoag...ains high. No antithrombotic or newer antiplatelet drug has been shown to reduce the risk of death after a heart attack. Salim Yusuf, D.Phil., F.R.C.P.C., ...Communication between primary-care physicians and patients can reduce medication-related problems
...op strategies for decreasing the number of adverse drug events (ADEs) instances of injury arising from pr...to determine whether it constituted a true adverse drug event. The researchers found that while many patients experienced ADEs, they failed to report a surp...