UNC Researchers Testing First In New Class Of AIDS Drugs
...hapel Hill are testing the first of a new class of drugs thatattacks HIV before it enters the cell and may ... a new drug on HIV patientswho have failed lots of drugs and provides important information that will allowus to go on and study T-20 in combination with oth...Immunex's TRAIL Molecule Shows Potential As Anti-Tumor Agent
...opment, manufacturing andmarketing of prescription drugs and over-the-counter medications. It is also aglobal leader in vaccines, biotechnology, agricultural products, and animalhealth care. NOTE: This news release contains forward-looking statements that involve risksand uncertainties, including risks a...New Protease Inhibitor Could Thwart AIDS Resistance To Current Drugs
...s the world's largestscientific society. Most AIDS drugs disable the human immunodeficiency virus (HIV) by ...e tries to overwhelm HIV with two or threeof these drugs simultaneously in a so-called "combination therapy," but eventhis approach eventually loses effectiv...Far Few Drugs Are Tested On Children
...till face similar risks today. The vastmajority of drugs have never been tested on children, forcing doctor...ith them ortheir health authority, rather than the drugs company. "Every paediatrician and GP caring for children faces this problem on adaily basis,...Duke Doctors Can Now Cure Most Babies Born With Fatal Immune Disease
...st, the infantis spared the toxic "anti-rejection" drugs normally given to suppress thedonor's T-cells. Second, and more importantly, T-cell depletion opens the door for dozensmore infants to be saved each year, meaning that a full genetic match is nolonger required for successful transplant. A hal...Women Who Have Invasive Cervical Cancer Benefit From Addition Of Chemotherapy To Radiation Treatment
... were shown to benefit from takingchemotherapeutic drugs while receiving radiation therapy. The study was l...s. Half of the women inthe study also received the drugs cisplatin and 5-fluorouracil during at leastthe first and fourth weeks of radiation treatment. About......quencing and a more frequent administration of the drugs athigher doses. Under current standards of care, the best that a patient withadvanced colon cancer can expect is a reduction in the mortality rate from 60percent to 50 percent. With this treatment we hope to get that down to 5percent." Van ...Percutaneous Electrical Nerve Stimulation May Offer Dramatic Short-Term Relief For Chronic Back Pain
...theprospect of avoiding the side-effects caused by drugs and other invasivetherapies. They said they are hopeful that PENS can become an integral part ofevery comprehensive pain-care program. Indeed, there has been an increase in theapplication of complimentary medical approaches such as this to managing p...Insulin Resistance And Obesity Avoided In Genetically Modified Mice, As Reported In Science
...ists has identified apotentially useful target for drugs to treat type II diabetes and obesity. Inthe scientists' experiments, genetically engineered mice lacking a specificenzyme were able to resist weight gain and to avoid the decreased sensitivity toinsulin that characterizes type II diabetes, even when...New Book (And Web Site) Use 'Currency' Of Aging To Guide And Motivate Healthy Choices
...rms, he could not assess the 'net present value'of drugs designed not to cure current disease but to prevent it in thedistant future. So we did some quick calculations and decided that takinghis medicines made him the equivalent of four years younger. Ever since,he has taken them religiously." In exchange,...Heart Valve Abnormalities Examined In Relation To Duration Of Diet Drug Use
... and racialdifferences between the group that used drugs and the group that didn't. Forexample, there were more white women in the treated group compared to thecontrol group. "It's the best study that can be done given the nature of theissue," he said. Working with him on the study were, fr...Scientists Link Body Weight Regulation And Immune System Control
...to havealterations in mahogany-attractin, and that drugs might be developed that affecthow mahogany protein functions."...Space Research May Accelerate Development Of Flu-Fighting Drug
... In the future, a new class of prescription drugs called neuraminidaseinhibitors offers the prospect...ies and to determine the effectivenessof potential drugs on the flu virus protein. "By analyzing space-grown crystals of the influenza virus, we were......studies, including two trials of anti-inflammatory drugs for ARDS. The results of the ARDS study will be presented at the annual meeting ofthe American Thoracic Society in San Diego, CA on April 26, 1999. Participating centers and affiliated hospitals in the ARDS Network are: The Cleveland ..."Plugs" For Drugs Promise Mightier Medicines
... exerted major efforts to invent a way ofreleasing drugs into the blood in a more balanced manner whileprol...vered by a patent, may be used to convert injected drugs into oralmedications. To commercialize the new method, a start-up company, LAPID Pharmaceuticals Ltd...NIA Launches National Study To Treat Mild Cognitive Impairment
...Canada. This study will test theusefulness of two drugs to slow or stop the conversion from MCI to AD. Thetrial will evaluate placebo, vitamin E, and donepezil, an investigational agentapproved by the Food and Drug Administration for another use. Vitamin E(alpha-tocopherol) is thought to have antioxidan...Novel Biological Interaction Found To Explain Blood Vessel Growth To Tumors
...depleted. And it suggests a new route todeveloping drugs that block angiostatin. "Instead of using the whole angiostatin protein as a drug to stop tumorangiogenesis, as efforts are now underway to do, it may be possible to design asmall molecule that will do what angiostatin does -- turn off ATPsynthase,"...New Chemicals Could Lead To First Bone Growth Pill
...cientist Nand Baindur,Ph.D. There are currently no drugs available to help grow bone. Researchers havetried givingpatients proteins that the body naturally uses to stimulate osteoblasts, such asparathyroidhormone and bone morphogenic proteins (BMPs). But, according to Dr. Baindur,thoseclinical trials hav...Should Doctors Urge Patients To Take Breaks From Their Drugs?
..." from their drug treatments. Cocktails of drugs that disable two key viral enzymes have transformedthe lives of people with HIV, allowing some patients to rise from their sickbeds. But several AIDS experts now suggest that a sequence of two-week breaksfrom this "triple therapy" may boost a vital c......imvastatin, are a new class ofcholesterol-lowering drugs that are easy to take, cause few side effects and ...reported that lowering LDL cholesterol with statin drugs isassociated with lower rates of heart attacks -- which is why the American HeartAssociation recomme...