Could Cardiovascular Drugs Be Linked To Suicide?
...ble associations between the use of cardiovascular drugs and suicide and the results of this study are publ...onsidered). Furthermore, in a five year study of drugs for high blood pressure the authors found a fivefold increase in the incidence of suicide, in users ...Tighter Chemical Binding = Better Meds
...nual meeting. The Yalechemists also have analyzed drugs that regulate the protein thrombin,which is import... laboratory isthe development of improved anti-HIV drugs that counter mutant strainsthat are resistant to current drugs, such as AZT and the proteaseinhibito...Diuretics And Beta-Blockers Are Best Drugs To Combat High Blood Pressure, Study Finds
...tensive drug, while others were taking one or more drugs from the list of common agents: diuretics, beta-blockers, ACEinhibitors, calcium channel blockers or sympatholytic agents that were notbeta-blockers. Some 54 percent took a diuretic, most commonlyhydrochlorothiazide, and 33 percent took a calcium ch......ies that might be adopted to design more effective drugs toindividually target these various molecules. ...tters act on different receptors could lead to new drugs that couldprovide good pain relief when combined with lower, less problematic doses ofmorphine, he a......gthe availability of new and more potent antiviral drugs and widespread use ofviral load testing to better gauge the effectiveness of these therapies.However, precise information as to the extent to which antiviral medication ingeneral, and type of antiviral combination regimens specifically, may havecontr...... the Johns Hopkins Oncology Center, stated, "These drugs have thepotential to make a significant impact on ...itors, represent some of themost active anticancer drugs in existence. Due to formulation problems,however, the great majority of camptothecins in developme......e treated with thepump in addition to clot-busting drugs died, Barron found.In contrast, death rates in pat...ortic balloon pump in combination withclot-busting drugs at these hospitals has the potential to save thousandsof lives each year." The pump treatmen...National Health Study Launched On The Internet
...ts. Said Williams, "The study could identify which drugs and medical treatments aremost effective, as well as drugs that have heretofore unrecognized effects, bothbeneficial and detrimental. It will provide both a n...Clinical Pharmacists Improve Outcomes Of Heart Failure Patients
...o be on a higherdose of ACE-inhibitors, a class of drugs which is very important in reducingfuture events a...sand patients -- in evaluating the side effects of drugs and their interactionswith each other," O'Connor said. "The types of interactions are very c...Anti-Clotting Drug May Cause Potentially Fatal Platelet Disorder
.... The cause is unknown,but in very uncommon cases, drugs other than ticlopidine, including penicillin,some anti-cancer drugs and oral contraceptives, have been associated with thesyndrome. TTP has been considered an ...New Research In Battling Alzheimer's Impact On Memory
...ki, Ph.D., this information could beused to design drugs that might prevent either this initial step or itscontinuation into Alzheimer's disease. A sequence of 40 to 42 amino acids, aso-called beta-peptide, is the major protein component that eventuallyaggregates and precipitates as plaque -- an insoluble...Need For HIV Guidelines For Health Workers In Developing Countries
...is not able to afford the cost and storage of such drugs then should health workers be given a personal supply before travel? Gilks and Wilkinson conclude that there is a need for realistic, usable guidelines for both for those working overseas in medical environments and for their employers. Contact: Dr ...Successful Cancer Therapy May Doom Later Treatments To Failure
...lk about multidrug resistance if you can't get the drugs into the tumor," says Jain. He believes there is a...pic doors, they must also think about aiming their drugs at a moving target -- blood vessel pores that change in size over the course of treatment. Yet drug...Clot-Busters As Effective As Surgery To Clear Blockages In Legs
...agrees, saying the studydoes support the idea that drugs should be a part of thetreatment regimen. "These drugs have a useful place in thetreatment of acute arterial blockages in the legs. Urokinasespares fairly ...Studies Look At Threshold Effect Of Cholesterol-Lowering "Statin" Drugs
...hers found that the benefits of the popular statin drugs -- shown to sharply reduce heart attack risk in in...-lowering drugs," he adds. In WOSCOPS, pravastatin drugs significantly reduced heart attacks among patientswith LDL levels of 160 mg/dL or higher, and other ...Researchers Identify Candidate Immunosuppressant With Fewer Side Effects
...ular Cell. The two main immunosuppressant drugs used today, cyclosporin A andFK506, prevent the re...signaling pathway that activates T cells. But both drugs can cause kidney andnervous system damage, making them unsuitable for wider clinical application.The...Beware Of Adverse Drug Reactions
...should always be aware of the toxic profile of the drugs they prescribe and that they should be ever vigilant for the occurrence of unexpected adverse reactions. Contact: Dr Munir Pirmohamed, Senior Lecturer in Clinical Pharmacology, Department of Pharmacology and Therapeutics, University of Liverpool, Liv...Chemical Society's Highest Award Goes To Ronald Breslow
...ey Medal for his efforts to developcancer-fighting drugs and other useful chemicals as well as for his service inmaking the science more accessible to the public. The gold medal will bepresented to him at the Washington-based Society's national meeting next spring. "I think it's nice to aim to unde...Identification Of Brain Areas Could Help Eliminate Side Effects Of Pain Medication
...on. "Opioids such as morphine and morphine-like drugs still comprise the major tool for the clinical management of pain even though the drugs can have some very serious side effects," explains Ralph Lydic, Ph.D., professor of anesthesia. "T......on of angiostatin, one of the promising new cancer drugs beingheralded nationally this week. Angiostatin a... more studies involving the basic science of these drugs are needed. Research now under way in Castellino's laboratories will attempt to address someof these...