WFU And IntraVec To Develop Innovative Cancer And HIV Treatments
... finds its way to the tumor cells. And most cancer drugs also damageother dividing cells, including normal cells. In human patients, the scientists hope that the altered toxic cells willserve a continuing surveillance function, going after remaining cancer cellsthat otherwise would multiply again ......tions render the retrovirus resistant to antiviral drugs such as AZT. Once HIV invades a human cell, rever...umb almost touching the finger nearest to it. Most drugs that target RT mimic nucleotides. When the drugs are incorporated into DNA strands in the place of n...Now Is Time To Design Brain-Saving Drugs Specifically For Children, UCSF Neurologist Says
...entists are spurred partly by the history of adult drugs used on children-- some are ineffective, some have... stage of brain development. That also means that drugs must be designed to avoid damaging the developingbrain. An ideal drug would succeed by saving a chil...New drugs, diagnostic tests, software needed to prepare US cities for chemical, biological attacks
... damage caused by a terroristattack, including new drugs and vaccines to combat anthrax and smallpox, fasterand easier-to-use chemical detectors and diagnostic tests, and communicationssoftware to improve disease surveillance and to provide information aboutpossible attacks. "Although preparing for and res......Signal is developing new classes of small molecule drugs that potently andselectively control the mechanism...evelopment of novel classesof anti-resorptive SERM drugs for the treatment of osteoporosis. To expeditethe discovery and validation of these drugs, Signal...Promising New Drug Uses Antibody Targeted Chemotherapy To Fight Leukemia
...e a relapse. Because current chemotherapy drugs to treat AML are non-specific - harming goodas wel...st with chemotherapyregimens that involve multiple drugs that increase the likelihood of adverseside effects and drug-drug interactions. It is administered ......is one of the statin class of cholesterol-lowering drugs called HMGCoA inhibitors. Sacks reports that, compared with those in the placebo group, diabetic patientswho received pravastatin had a 25 percent reduction in relative risk of havinganother heart attack. The relative risk of needing coronary artery ......Inc. Maxim Pharmaceuticals is developing advanced drugs and vaccines for cancer andinfectious diseases. Maxim's focus is to develop novel products that includepharmacoeconomic and disease management benefits such as out-patient therapy,improved clinical efficacy, higher level of safety, cost-effective tr...Science Is On The Trail Of Sexual Predators That Dope Women
...udes Valium. But it is 10 times as potent as other drugs in the class, andso is used in much smaller quantities, making it very difficult to detect.Existing antibody tests, developed for other benzodiazepines, often missRohypnol. Kieran Walshe and his colleagues at University College Dublin havede......searchersbelieve that the estrogenic properties of drugs such as raloxifene preventosteoporosis and may be target to prevent heart attacks in postmenopausal women. Raloxifene is the only selective estrogen receptor modulator (SERM)available in the United States to protect postmenopausal women again...Discovery May Boost Effectiveness Of Chemotherapy
... anti-cancerdrugs out of cells rapidly, before the drugs could get to the nucleus of thecancer cells and de...genesthat cause resistance." One of the drugs these resistant cancer cells are able to pump away ismitoxantrone, a common first-line chemotherapy ..."Super" Aspirin Does Super Job In Fighting Heart Attacks
... the American Heart Association. Like aspirin, the drugs called a platelet IIb/IIIa receptor blockers keep ...archInstitute in Durham, N.C. "This new family of drugs works harder at making platelets less sticky, and theydo it to a far greater degree than many other ...Radically New Type Of Surgery Tested On First Patient
... blood vesselabnormalities, delivering therapeutic drugs or chemotherapy agents to parts ofthe brain, cardi...be much more innovative indelivering electrodes or drugs for direct therapy of a variety of braindiseases." The following visuals are available: The Magneti...Views Of Tamoxifen And Synthetic Estrogen In Action Provide Clues For Designing Better Drugs
...ects. "The goal is to figure out how to make drugs thatretain the benefits of estrogen for brain, bon...sco. "Thissets the stage for intentional design of drugs with precise and selectiveaction." Estrogen has many health benefits. It delays the buildup of arter...American Heart Association Comment: Results Of Cardiac Insufficiency Bisoprolol Study II (CIBIS-II)
...weshould be looking for opportunities to use these drugs rather than avoid them."Beta-blockers have not been routine drugs for heart failure due to their"depressive" effects on the heart. However, new information about the...... this may markedly extend the ability of antiviral drugs toHIV-1 to control viral replication long term." Part of the research team's effort was the development of techniques to measurewhether the infused CTLs reduced the number of HIV-1 infected cells. Brodie andPatterson developed a method to measure th...Patent Received On Drug Delivery System
...man testing. The new system includes incorporating drugs into macrophage cells and deliveringthe cells intravenously to patients. Macrophage cells, which are localized incertain parts of the body, have a homing mechanism, which causes them to returnto their original location. "This approach for the treatme...UK Allied Health Professor Receives Patent On Using Lithium With AIDS Drugs
...oxic therapies. Gallicchio proposesthat combining drugs commonly used for AIDS patients with lithium salts..."It will remain to be determined whether these new drugs willactually reduce the amount of infectious virus by inhibiting a process that isessential for vira...New Theory May Explain Ritalin Action In Hyperactivity
... like normal humans. To understand why the drugs had such opposite effects on the two groupsof mice... dramatic reduction in hyperactivity, as did other drugs thateither directly activated serotonin receptors or increased brain serotoninlevels, the researcher......d programmedfor the delivery of precise amounts of drugs at specific times. The chip behind thei...mplants and patches currently onthe market deliver drugs continuously over time; the new chip would "allow youto control not only the amount of drug released...