Tag: "ductal" at medical news
Sharing clinical trial results with participants may be beneficial
...ncer trial of breast excision alone for women with ductal
carcinoma in situ. The study was stopped early because of a high rate of local recurrence. 85 (90%) of the 94 participants who responded chose to receive results; these women were more educated than those who chose not to. 68 (80%) patients received...
Non-invasive and invasive breast cancers share the same genetic mutations
... a common form of early stage breast cancer called ductal
carcinoma in situ (DCIS). Led by Elizabeth B. Claus, M.D., associate professor in the Department of Epidemiology and Public Health (EPH) at Yale School of Medicine, the Yale team examined genetic and environmental risk factors for the development of ...
Poor response to chemotherapy does not mean poor outcome for patients with rare breast cancer
...e same way that it does for patients with invasive ductal
carcinoma. Results of the study show women with th...ave a better prognosis even compared with invasive ductal
carcinomas that are hormone receptor positive (typically a better prognosis group). Use of hormonal ...
Celecoxib shows surprising activity against estrogen receptors
...man agreed to undergo a fine needle aspiration and ductal
lavage to remove breast epithelium cells both before and after six months of celecoxib treatment. These samples were available for analysis in 26 high-risk women. The researchers assessed the difference in estrogen receptor levels before and after tr...
Jefferson scientists find way to see breast cancer activity from outside the body
...d also be used to detect precancerous zones, as in ductal
carcinoma in situ, and the spread and recurrence of cancer. The researchers hope to conduct a clinical trial of their probes in suspected cases of breast cancer, and eventually, in other cancers as well. They are publishing their results testing for...
Chemoprevention backgrounder: Working for a future of cancer chemoprevention
... Arun uses a minimally invasive technique known as ductal
lavage to collect and examine cells from breast milk ducts. She says that, so far, "COX-2 overexpression is strongly implicated in progression of breast precancer to malignancy." Retinoic acids also are being tested as a breast cancer chemopreventive...
Ductal lavage may not detect breast cancer, study finds
...t in the procedure was spurred by a study in which ductal
lavage detected cancer in four of 11 women who had.... To determine the sensitivity and specificity of ductal
lavage in the presence of known breast cancer, Seema A. Khan, M.D., of the Lynn Sage Comprehensive B...
Ductal lavage may not detect breast cancer
...tudy raises serious questions about the utility of ductal
lavage as a cancer detection test and shows us that women should not be offered ductal
lavage as a method of breast cancer detection. Mammography and physical examination remain the most...
Breast cancer in men increasing
...common types of breast cancer in men were invasive ductal
or unclassified carcinomas (93.4 percent) and papillary carcinomas (2.6 percent). Larger tumor size and axillary lymph node disease were independently associated with shortened survival. Tumor grade and receptor status were not. The authors conclude:...
Largest study of its kind finds male breast cancer on the rise
... most common types of cancers in men were invasive ductal
carcinoma, found in 93.4 percent of the men, and papillary carcinoma, which accounted for 2.6 percent of the cases. Yet despite these differences, five-year, 10-year and median survival were not different between men and women, investigators say. Al...
First multi-center trial shows cryosurgery successful at treating some early-stage breast cancer
... those women with a type of cancer called invasive ductal
carcinoma who did not have significant ductal
carcinoma-in-situ, a non-invasive breast cancer, in the surrounding tissue. Cryoablation was not sh...
Conservation treatment or mastectomy for DCIS?
...is study offered reassuring evidence to women with ductal
carcinoma in situ (DCIS) that if they chose to have only the affected area of their breast removed (lumpectomy) rather than the whole breast removed (mastectomy), it would make no difference to their chances of surviving the disease. Even although th...
Treatment of ductal carcinoma in situ varies widely in United States
A new study has found that treatment of ductal
carcinoma in situ (DCIS), a group of abnormal cells confined to the breast ducts, varies widely in the United States. Treatment ranges from potential overtreatment with aggressive surgical therapy to possible undertreatment by not providing radiation...
Freezing technique kills majority of small malignant breast cancers
...rs, and most were classified on biopsy as invasive ductal
carcinoma. One patient had invasive colloid carcinoma, and another's biopsy showed ductal
carcinoma in situ (DCIS), a non-invasive pre-cancerous condition, in addition to invasive ductal
HRT and breast cancer: better prognosis more likely due to frequent screening than hormone use
...r cases, it is more treatable than the more common ductal
variety, which arises in the ducts that carry milk from the lobules to the nipple. Daling and colleagues earlier this year reported that the incidence of lobular cancer has risen 65 percent during the past decade, a trend that may be due to the incre...
High nuclear grade associated with recurrence of in situ breast lesions
Women with ductal
carcinoma in situ , a non-invasive form of breast cancer, are more likely to experience a recurrence after treatment if their DCIS is of a high nuclear grade or is detected by palpation during a breast examination, according to a study in the Novemb...
Alcohol use increases the risk of hormonally sensitive breast cancers in postmenopausal women
...increased risk) and a 50 percent increased risk of ductal
cancer," Li said. While lobular breast cancer, whi...de. While somewhat more difficult to diagnose than ductal
breast cancers, lobular carcinomas tend to be ER+ and PR+, which means they are more responsive to h...
US women endure twice the surgical biopsies as British for same cancer detection rate
...r pathology databases. Cancers, either invasive or ductal
carcinoma in situ, within 12 months of a positive screening mammogram were counted. Recall, biopsy, and other further diagnostic procedures were calculated per 100 screening mammograms. Biopsy types including fine needle aspiration, core biopsy, open...
North American mammographers prone to more false positives, study finds
...d abnormal, the percentage of women diagnosed with ductal
carcinoma in situ (DCIS), and the percentage of women diagnosed with minimal disease. The percentage of mammograms deemed abnormal by North American programs was 2 to 4 percentage points higher than it was in programs in other countries, even after...
MRI may help find missed breast cancers in high risk women
...ng the study period, two of the 54 women developed ductal
carcinoma-in-situ (a preinvasive breast condition) and one woman developed invasive breast cancer. All three women had reportedly normal mammograms within six months of their MRI. No woman on the study has yet developed cancer within 12 months of a n...