Tag: "dystrophy" at medical news
Mayo Clinic researchers identify new form of muscular dystrophy in adults
...use it increases the understanding of the muscular dystrophy
disease process and the role genes play in it. The...h The identification of this new form of muscular dystrophy
highlights the importance of scientific collaborations and the integration of different kinds of dat...
JCI table of contents, January 20 2005
... the rapid recovery of amyloid-associated neuritic dystrophy
in PDAPP transgenic mice. AUTHOR CONTACT:David M. Holtzman Department of Neurology, Washington University, St. Louis, Missouri, USA. Phone: 314-362-9872; Fax: 314-362-2826; E-mail: Holtzman@neuro.wustl.edu . View the PDF of this article at: http...
New guideline: Corticosteroids recommended for duchenne muscular dystrophy
...e beneficial in the treatment of Duchenne muscular dystrophy
and can be offered as a treatment option, accordin...e American Academy of Neurology. Duchenne muscular dystrophy
is a genetic disorder linked to the X-chromosome. It is the most common form of muscular dystrophy
Stem cells to the rescue - or not?
...an an animal model of cardiomyopathy and muscular dystrophy
to determine whether these stem cells would be recruited to skeletal and cardiac muscle to restore delta -sarcoglycan expression. Surprisingly, upon examination of many thousands of muscle cells, the authors found that while donor cells readily engr...
Creatine is safe, but not effective, in pediatric neuromuscular disease
...uscular disorders: two boys with Duchenne muscular dystrophy
(DMD), two girls with limb-girdle muscular dystrophy
(LGMD), and one girl with chronic inflammatory demyelinating polyneuropathy (CIDP). All three condit...
Rochester chosen to focus on rare neurological diseases
...amed by NIH as one of three newly created muscular dystrophy
cooperative research centers. The other six rare-disease centers established this week by NIH will focus on a variety of topics, including rare lung diseases, bone marrow failure, and genetic steroid disorders. "Funding research on rare diseases is...
Passing stop sign cures gene disease
...nsible for many cases of cystic fibrosis, muscular dystrophy
and haemophilia. An experimental drug called PTC12...aborating with the company. In mice with muscular dystrophy
the drug restores expression of the dystrophin protein found on the surface of muscle cells. Tests s...
New centers boost muscular dystrophy research
...ational studies on several other types of muscular dystrophy
to accelerate the development of new therapies. Th...year for 3 years for additional projects. Muscular dystrophy
is characterized by progressive weakness and degeneration of the skeletal muscles (voluntary muscles...
UCSD researchers identify chromosome location for 2nd form of Joubert syndrome
...ed panting respirations, balance problems, retinal dystrophy
and moderate visual impairment. The study's authors noted that the variability of symptoms in the affected individuals suggests that there may be genetic modifiers that influence the disease severity and expression of symptoms. Gleeson, who has stud...
Muscle stem cells show promise against muscular dystrophy in mouse model
... dystrophin to damaged muscles in a mouse muscular dystrophy
(MD) model, according to a study supported in part by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS). The research, carried out by Johnny Huard, Ph.D., and his colleagues at Children's Hospital of Pittsbur...
Muscular dystrophy mouse model yields potential growth factor treatment
...ouse model a cross between a strain with muscular dystrophy
symptoms and another with high levels of IGF-I...s. "This is indeed good news for the muscular dystrophy
community," said Stephen I. Katz, M.D., Ph.D., director of NIAMS. "The mouse model has helped our ef...
Enzyme halts muscle waste in mouse models of most-common childhood muscular dystrophy
...scle destruction associated with Duchenne muscular dystrophy
(DMD), the most common childhood form of muscular dystrophy, is halted in mice when supplemental amounts of a naturally occurring enzyme are added to the skeletal muscle. These results from researchers at the University of California, San Diego (UCS...
McCaw/Muscular Dystrophy Association fund supports UW recruitment of internationally noted gene therapy researcher
...r. Few patients with the Duchenne form of muscular dystrophy
live into the third decade of life. Chamberlain has studied the location of the Duchenne muscular dystrophy
gene in the chromosome, and the genetic expression of dystrophin, a substance needed to regulate mus...
Frank family pledges $10 million to support education of physician-scientists at the University of Chicago
...ocess he helped develop a mouse model for muscular dystrophy
that was a crucial stepping stone in the development of human gene-therapy trials. "Learning the techniques of human genetics is a great taking-off point for where science is going now and for how medicine will be practiced in my career," said Hack...
UI study identifies mechanism that causes cardiomyopathy, exacerbates muscular dystrophy
...diomyopathy, which exacerbates limb-girdlemuscular dystrophy
(LGMD). "Our results have important implications ...ts developing gene therapyfor limb-girdle muscular dystrophy
and for neurologists who treat musculardystrophy patients with cardiomyopathy," said Kevin Campbell,...
Temples Virtual Lab Helps Disabled Students
...ies. There, while observing afriend with muscular dystrophy
using voice-recognition technology to "talk" to acomputer, he thought of IMITS. "I just put the two together," Butz recalls. "I had all the software to put avirtual laboratory together, so I applied to the NSF to get financial supportfor its develop...