Tag: "efavirenz" at medical news

Depression linked to insomnia in HIV patients

...ffect. With the exception of one medication called efavirenz (Sustiva), Reid says there is not enough evidence to suggest that antiretroviral drugs contribute to insomnia. Reid and colleagues identified only two studies of treatments for insomnia in HIV patients, including one study of acupuncture therapy and ...

Nevirapine is better than efavirenz at raising 'good' cholesterol

... data suggest that nevirapine may be preferable to efavirenz in HIV-infected adults who have increased cardiova...nevirapine at keeping HIV infection under control; efavirenz is also advantageous because patients only need to take it once a day, whereas nevirapine must be ta...

FDA approves EPZICOM

...when given in combination with EPIVIR 300mg QD and efavirenz 600mg QD. Product Information HIV medicine...side effects seen with EPZICOM in combination with efavirenz were trouble sleeping, depression, headache, tiredness, dizziness, nausea, diarrhea, rash, fever, st...

Weekly cycles of once-daily anti-HIV drugs could reduce cost of HIV treatment

...h the drugs didanosine (ddI), lamivudine (3TC) and efavirenz for 7 days, followed by 7 days off the antiretrovi...ls, a finding they attribute to the persistence of efavirenz in the blood throughout the 7-day-off-therapy cycle in the current study. The authors note that stri...

Combination, order of anti-HIV drugs make a difference in first-time recipients

...oside RT inhibitors, with one group also receiving efavirenz (EFV), a non-nucleoside RT inhibitor, and the other receiving nelfinavir (NFV), a protease inhibitor. Two other groups began treatment with zidovudine (ZDV) and lamivudine (3TC), two other nucleoside RT inhibitors, combined, again, with either EFV or...

One combination of AIDS drugs appears better for starting treatment

...ine (ZDV, also known as AZT), lamivudine (3TC) and efavirenz (EFV) were successfully treated for a longer period of time. "We've been fortunate to have a variety of choices for antiretroviral therapy," says Gregory Robbins, MD, MPH, of the Massachusetts General Hospital. "But many had previously believed tha...

Interim analysis comparing TDF to EFV in combination with 3TC + ABC

...y comparing tenofovir disoproxil fumarate (TDF) to efavirenz (EFV) - both given in combination with a fixed-dose investigational co-formulation of Epivir (lamivudine) (3TC) and Ziagen (abacavir sulfate) (ABC) - for the treatment of HIV showed that subjects in the TDF- containing arm experienced an unacceptably...

Study assessing once daily Abacavir (ABC) in a once daily ART regimen

... open-label Epivir (lamivudine) (3TC) 300mg QD and efavirenz (EFV) 600mg QD. The ABC QD dosing regimen provided an antiretroviral response over 48 weeks that was shown to be non-inferior to the approved ABC BID dosing regimen, according to study results. "There are a number of antiretroviral drugs that have...

Study evaluates Abacavir, Lamivudine and Efavirenz versus Zidovudine, Lamivudine and Efavirenz

...avir sulfate) (ABC), Epivir (lamivudine) (3TC) and efavirenz (EFV) has been shown to be non-inferior to the oft...three-drug combination of abacavir, lamivudine and efavirenz provided a potent antiretroviral response over 48 weeks and was shown to be non-inferior to zidovidi...

Tipsheet on XIV International AIDS Conference

...ination of zidovudine (ZDV), lamivudine (3TC), and efavirenz (EFV) appears to be particularly beneficial compared with other three-drug regimens, including the similar combination of ZDV, 3TC and nelfinavir (NFV). Researchers found no evidence of a difference between three-drug regimens using stavudine (d4T) ...

Drug combinations reduce HIV levels in untreated patients

...cleoside" reverse transcriptase inhibitor (nNRTI), efavirenz (Sustiva) an NRTI, stavudine (Zerit) , or a protease inhibitor combination (PI), amprenavir/ritonavir (Agenerase and Norvir). Protease inhibitors interfere with the enzyme that HIV needs to snip apart the protein it creates in reproducing itself. S...

Study evaluates dosage adjustments of Agenerase

...(amprenavir) capsules in HIV patients treated with efavirenz or nevirapine, antiretroviral (ART) agents known t...ed patients received Agenerase in combination with efavirenz or nevirapine with treatment based on phenotypic or genotypic resistance testing. Efavirenz and nev...

Drug combination shows potent punch against HIV in children

... One novel feature of the trial was that levels of efavirenz and another drug, nelfinavir, were measured in eac...d the U.S. Food and Drug Administration to approve efavirenz (trade name Sustiva(r)) in September 1998 for use in children. The current results reinforce those e...

Study Shows Efavirenz Promising In Treating Pediatric HIV Infection: Leads To Approval Of New Drug For Testing HIV-Infected Children

...ety, dosing and antiviral effect of efavirenz in combination with antiretrovirals in ... "This study demonstrates that efavirenz used in combination with other antiretrovirals can have potent antivir...

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