Researchers Gain Insights Into Drugs Used For Manic-Depression
..." he said. "This seems to occur by thesimultaneous elevation of IP3 and the down-regulation of the IP3 receptor." In the current research, the UW scientists showed that, likelithium, valproate also stimulates glutamate release and IP3 accumulationin the brains of mice. They also saw that each drug tri...... St. John's Wort and ma huang--both taken for mood elevation and weightloss--may also be MAO inhibitors, Maher said. Although nobody has been identified as having developed lung or heartdiseases after taking Prozac and Sudafed, for instance, Maher says that thispossibility needs to be investigated care...Study Shows Hormone Replacement Therapy Does Not Elevate Breast Cancer Risk
...g-term ERT, however, may be associated with a mild elevation in breast cancerrisk for all women, and ERT withou...hought that these women might have an even greater elevation inbreast cancer risk if they used ERT. Until this study, however, littleinformation has been availa...UT Southwestern Study To Test Efficacy Of St. John's Wort For Treatment Of Depression
...on." St. John's wort, which has been used for mood elevation over many centuries, hasgrown in popularity recently, along with ginseng and other products considerednatural. Participants in the three-month study must be 18 years of age or older. Eachwill be given the St. John's wort drug; sertraline, a serotonin......or a type of heart attack known as anon-ST-segment elevation heart attack. This type of heart attack may seem lowrisk at first, but, over a period of two years or so, it can be as lifethreatening as other kinds of heart attacks. The new guidelines indicate thatnewer classes of medicines -- glycoprotein IIb/III...New links found between an 'iron' gene mutation and increased risk for heart attack and stroke
... carriers of the gene. Carriers often have a small elevation in their iron storage levels that may beresponsible for the observed increase in heart attacks. Carriers are rarelyaware of their status and usually have no symptoms until a heart attack orstroke occurs. In an accompanying editorial, Jerome L. Sulli...Anti-HIV treatment improves immune system and fights sight-threatening eye infection
... AIDS physician and senior author. "We measured no elevation of HIV viral load in the plasma," Dr. Polis said, "and CD4+ T cell counts increased significantly over time, giving us more signs that HAART is restoring some independent immunologic control in our patients." Despite these positive findings, Dr. Whit...Novartis receives FDA approval for LESCOL XL 80 mg
...d at 12 weeks following initiation of treatment or elevation in dose. If serum transaminase levels rise, monitor more often; if they persist at three or more times the upper limit of normal, discontinue LESCOL or LESCOL XL. Treatment with LESCOL and LESCOL XL should be discontinued if myopathy or rhabdomyoly...Rise in non-communicable diseases commands pharmaceutical scientists attention
...plement St. Johns Wort in hopes of additional mood elevation (JAMA, 1998: 280, pgs. 1569-1575). A new study released at the AAPS Annual Meeting shows that the effect of many prescription medications may be dramatically reduced when combined with St. John's Wort. In fact, this study shows a staggering 50 percen...Impulsiveness, aggression, alcohol and adolescents
...diagnosed as conduct disorder) - had a significant elevation in cortisol response, which correlated with measur...iminished response, our findings suggest that the elevation of cortisol in adolescents with alcohol use disorders and conduct disorder - which reflects an incr......ssociation isn't clear, we suspect that the sudden elevation in blood pressure that occurs immediately after using cocaine may cause an existing aneurysm or arteriovenous malformation (AVM) in the brain to rupture." Several clinical studies of stroke among cocaine users have found a high frequency of aneurysm...High homocysteine levels may double risk of dementia, Alzheimer's disease
...participant would develop AD and each 5 mmol/liter elevation increased the risk of AD by 40 percent. The analysis showed further that people with consistently high levels of homocysteine throughout the period of the study were at highest risk for dementia and AD. The researchers also examined whether the earl...Imaging tool helps locate recurrent prostate cancer
...ll but three of the 255 men in the study showed an elevation of PSA levels, the only sign that their cancer might be returning. Recurrent disease was detected by the capromab pendetide scan in 184 of the men (72 percent). Furthermore, in these patients, the scan showed the extent of the disease: One-hundred an...UT Southwestern researchers identify mechanisms by which cocaine elevates blood pressure
...ment strategies for cocaine-induced blood pressure elevation and related complications including stroke and acu...rapid heartbeat and increased cardiac output. This elevation in blood pressure, if severe or persistent, can lead to damage of multiple vital organs such as the ...Light-weight heparin has heavy-weight results in heart attack treatment
...ents in the study had what are known as ST-segment elevation myocardial infarctions, which are the most severe type of heart attack.We have very encouraging data but the evidence is not yet sufficient to say that enoxaparin should be standard treatment for severe heart attacks, says Elliott Antman, M.D., assoc...Common treatment endometriosis linked to ovarian cancer, say University of Pittsburgh researchers
...anazol. Women taking leuprolide had no significant elevation in risk. "While the number of women studied is small, the results are telling, and they warrant further studies on a larger scale," said the study's principal investigator, Carrie Cottreau, Ph.D., assistant professor of obstetrics and gynecology, Uni...Proven heart therapy used in only 25 percent of cases
...s with chest pain (angina) and have non-ST-segment elevation myocardial infarction (NSTEMI) or unstable angina. It is estimated that about 715,000 Americans experience NSTEMI or unstable angina each year. "Despite the fact that these drugs have been proven effective in preventing death and heart attacks, they ...Less inflammation, better heart health in physically fit females
...ting women on a treadmill while speed and angle of elevation were increased every two minutes. The women continued on the treadmill until they reached their point of exhaustion. Each woman's treadmill time was adjusted for her age because fitness declines as the body ages, says LaMonte. Women in each of the...Hypertension is study focus of $10 million NIH grant to MCG
...ironment, genetics or both - but they believe that elevation explains increased sodium retention. They think this happens when the combination of stress and salt disturbs the body's balance of the vasoconstrictor, endothelin, and the vasodilator, nitric oxide. The truly novel part of the study is the idea tha...Better control of liver enzymes saves lives of HIV patients, says University Of Pittsburgh
...ciation with increased mortality suggests that any elevation in ALT and AST should be addressed." Elevations in these enzymes signal injury to liver cells and, in some cases, to other cells in the body. The condition can result from highly active anti-retroviral therapy (HAART), viral hepatitis or alcohol abus...