Tag: "elicits" at medical news

Newly identified gene cluster on mouse X chromosome provides insights into fertility

...ecause it has long been a mystery how testosterone elicits the formation of sperm in the testis," he says. "Based on our findings, we propose that testosterone binds to its receptor on Sertoli cells, which causes Rhox genes to be activated, which then turns on a genetic cascade that affects the neighboring g...

Success of experimental herpes vaccine builds momentum for human clinical trials

...sses many of its proteins within them, it not only elicits a broad spectrum of antibodies but also stimulates T cells, which directly attack infected host cells and release cytokines that further strengthen the immune response. The clinical trials of previous herpes vaccines suggested that T cells as well as...

Mayo Clinic discovers potential marker for aggressive kidney cancer

...ely toxic, can further sicken the patient and only elicits a response in 15-20 percent of all patients treated. This means 80-85 percent of patients are not significantly helped by it, but nonetheless exposed to its toxicity. "That's why we're so interested in this molecule," says Dr. Kwon. "We think th...

Cognitive behavioral therapy combined with antidepressant effective in treating adolescent OCD

...lective serotonin reuptake inhibitor (SSRI), which elicits its effects by increasing the activity of serotnin in the brain. CBT includes helping the children confront anxiety-evoking situations and refraining from performing compulsions in order to learn their fears are exaggerated or unrealistic. This is t...

Jefferson researchers find immune response, dosing keys to vaccine's success against melanoma

...ne is administered and the immune response that it elicits strongly influence whether or not a patient will survive five years." He and his colleagues report their findings in the current issue of the Journal of Clinical Oncology. An editorial accompanies the paper.The phase II trial examined the immunolog...

NIAID Ebola vaccine enters human trial

...h uses the DNA vaccine being tested in this study, elicits a stronger immune response and is important to pursue for individuals at high risk, such as health care workers. Dr. Nabel says that expanded human trials of Ebola vaccines using the prime-boost strategy could begin by 2005....

NIA statement on IOM testosterone report

...n that any trial be designed in such a way that it elicits useful information about the effects of testosterone therapy on a variety of conditions associated with deficiencies of this hormone. These problems, including frailty, disability and sexual and cognitive disorders, are serious concerns for older men...

Are hepatitis A vaccine boosters unnecessary?

..."Evidence is accumulating to show that HAV vaccine elicits immune memory that persists even after loss of detectable antibody. We recommend that reliance be placed on immunological memory rather than booster doses to protect against symptomatic infection. The recommended schedules for HAV vaccines consist of...

Fast-acting ebola vaccine protects monkeys

...as well, Dr. Nabel says. "The prime-boost strategy elicits a stronger immune response," he explains, "and it may be useful for preventive vaccines intended for hospital workers at high risk of exposure to the virus, for example."...

New HIV vaccine holds promise of global effectiveness

...to develop a multiclade vaccine. If our candidate elicits an effective immune response and proves safe in clinical testing, we will include additional components in subsequent trials in hopes of boosting this response. Ultimately, we aim to build a potent vaccine designed to prevent HIV infection." The t...

Kaleidescope eyes: the secrets of a novel gift

... synaesthetes being shown a letter that, for them, elicits a color experience. One synaesthete saw the letter 'A' as red. When shown a red 'A' and asked what color it was, she could quickly answer red. But when shown a green letter 'A' and asked what color the letter was, her response time was significant...

Early promise of simple screening for coeliac disease

...ich relies on biopsy. The enzyme transglutaminase elicits a specific immune response that underlies coeliac disease. Luis Sorell from the Centre for Genetic Engineering and Biotechnology, Havana, Cuba, and colleagues describe a simple and rapid test that detected these specific antibodies in the blood of pa...

American Thoracic Society Journal news tips for February (first issue)

...ergens have shown. This potent cockroach allergen elicits immunoglobulin E (IgE) responses in 60 to80 percent of allergic patients even at very low levels in the environment. In asthma, many allergic reactions involve antibodies of the IgE class. (Cockroach allergen exposure is strongly linked to asthma at...

Nabi StaphVAX elicits antibodies with in vitro activity against antibiotic-resistant Staphylococcus aureus strains

...s infections. StaphVAX is a bivalent vaccine that elicits antibodies against these two serotypes of the bacteria. According to Dr. Horwith, antibiotics kill bacteria by damaging the bacteria cell wall, or by interfering with replication. In contrast, the major means by which the immune system kills enca...

Mechanism found behind drug-free acceptance of transplants

...tetanus toxoid (TT) - a test antigen that normally elicits a response. "We figured that the donor antigen was triggering some sort of a reaction that muffled the normal DTH response," VanBuskirk said. To unmask what they believe...

Pain, itself, elicits pain relief, and does so through 'reward' pathway

...s the first physiological evidence that painitself elicits analgesia. It also provides a surprising twist on the perceived workings of the neuralcircuitry associated with gratification, said the lead author of the study,Robert W. Gear, PhD, assistant clinical professor of Oral and MaxillofacialSurgery in t...

Altered Brain Chemistry In Bulimia Nervosa Patients Persists After Recovery, According To UPMC Researchers

...that specifically affects the serotonin system and elicits hormonal andbehavioral responses. Dr. Kaye's team found that, compared to the healthy volunteers, the recoveredwomen had increased levels of the serotonin metabolite and more negative moodsand obsessions with perfectionism and exactness. The levels ...

Duke Study Suggests New Class Of Drugs Could Bypass Leptin Loop

...aches a certain proportion, it sends a signal that elicits some metabolic response to eliminatefat," Surwit said. Leptin travels through the bloodstream to the brain, where it targets clustersof neurons in the hypothalamus, a brain structure that regulates food intake and metabolism,among other functions. ...

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