Neurotransmitter-Induced Electrical Activity Identified As Key Regulator Of Synaptogenesis
...al, the postsynaptic membrane proper. By culturing embryonic spinal cord neurons and pharmacologic...anner. Knowing that glycine receptor activation in embryonic neurons can result in membrane depolarization and the opening of voltage-gated calcium ...Substance Discovered That Induces Hair Follicle Formation In The Mature Skin Cells Of Mice
...enin may be the long sought message that instructs embryonic cells to become hair follicles, suggesting possible treatments for premature baldness. "Beta-catenin can cause adult epithelial cells to revert to an embryonic-like state where they have the ability to choose to become a hair follicle," says Elaine ......cialized layer ofcells, called ameloblasts, in the embryonic tooth bud secretes amelogeninproteins. The amelogenins self- assemble to form the extracellular matrixwithin which the inorganic crystals of mineral start to form. "The earliestenamel crystals form in extremely long, thin ribbons and are rather bea...Sniffing Out The Promise Of Anti-Angiogenesis Therapy
...toic membrane was exposed to IM862 (thevessel-rich embryonic membrane is a standard tool for testing anti-angiogenicactivity), blood vessel formation was blocked. Later they found that the bloodvessel count in tumors implanted in mice was reduced when the tumor was treatedwith IM862. Its main effect, says Gill...New Technique Induces Growth Across Spinal Cord Injury
...r to that of peripheral nerves, orgrafts made from embryonic spinal cords, which have the capacity to regenerate. The success of those efforts, Woolf says, has been marginal. In the current study, Woolf and his colleague Simona Neumann, PhD, questionedthe assumption that environment made the key difference. ...Keck Foundation funds research to repair the injured spinal cord
...on. Thelong-term goal is to use cells derived from embryonic cells to replace losttissue. Such transplants migh...imit practicalapplication in humans. "We feel that embryonic stem cells may be the best sourceof cells to replenish cells lost from the spinal cord," says John M...Bacterial vaginosis seems to affect miscarriage in early pregnancy
...the fertilised egg in the IVF process or its early embryonic development. They suggest that this phenomenon could also be relevant to naturally conceived pregnancies and call for further research to be conducted in this area....Antibody solution may prevent adhesions after surgery
...uitous family of membraneglycoproteins involved in embryonic development, blood vessel formation, theimmune system, and wound healing. "As gynecologists, we're always concerned about post-surgicaladhesions," says Dr. Bruce Lessey, associate professor of obstetrics andgynecology at UNC-CH School of Medi......med brain cells migrate to specific regions of the embryonic brain, ensuring proper development of the cerebral...d. It provides some new information about the way embryonic neuronal cells divide and travel to end up in the right place at the right time in order to make the...Cell transplants offer hope of brain repair following stroke
...are found primarily in bone marrow in adults or in embryonic tissue lay down the blueprint for development of...d into damaged rat brains. Researchers harvested embryonic cortical cells (which come from the cerebral cortex the outer layer of the brain) for the transplan...Jefferson researchers have early evidence of bone marrow stem cells able to become brain cells
...vitti says. "The hope is that we won't have to use embryonic stem cells and aborted fetuses for stem cell lines." There is one caveat, she notes. To date, the new neurons revert back to their original undifferentiated state in two to three days. "The bigger problem to solve is how to keep them differentiated,...Adult stem cells from knee fat turned into cartilage, bone, fat cells
... without the same ethical concerns associated with embryonic stem cells." In the current study, the researchers took the fat pads from patients whose knee joints were removed during total joint replacement surgery.The researchers focused on specific cells within the samples known as adipose-derived stromal cel...Chemical attraction needed to launch an immune attack
... in the adult immune defense, but in all phases of embryonic development when, for example, neurons must find their way to their targets and muscle cells must interact and fuse. The role of chemokines or other chemical attractants uncovered in this study, creating zones that draw cells in depending on subtle c...UCSD team reviews pituitary gland development, from a common primordium to distinct cell types
...gland, from a common primordium in the roof of the embryonic mouth into an organ comprising multiple distinct endocrine cell types, is described by two University of California, San Diego (UCSD) School of Medicine researchers in a review published March 22, 2002 in the journal Science. M. Geoffrey Rosenfeld, M......r be moved by thought alone? Transplantation of embryonic stem cells in Parkinsons disease Does copper have a role in ALS? Blood test to detect Alzheimers developed Gene found for another idiopathic epilepsy Tuning into congenital tone deafness Reflection & Reaction Predictive value of MRI fi...First report of stem cell signal of intention to become specific neuron
.... Many people confuse all types of stem cells with embryonic stem cells, which are taken from the earliest stag...y. There are basically three types of stem cells: embryonic stem cells which can become any cell in the body, stem cells for a specific organ that can become an...Cord blood cells improve rats' neurological recovery from brain injury, new study finds
...lical cord blood (HUCB) cells as an alternative to embryonic stem cells. While studies of cellular therapies continue to grow in importance, the emphasis has been on neurological diseases like Parkinson's disease and stroke, and, more recently, on spinal cord injury. "This study is the first to suggest that h...Hormone prompts adult stem cells to differentiate into islet cells
...erefore, the ethical issues that surround fetal or embryonic stem cells can be avoided. Habener is working with the cellular therapy company ViaCell to design preclinical studies that will test whether adult islet stem cells might actually prove to be a cure for diabetes. ViaCell has licensed some of Habener?......eady has treated spinal cord injuries in rats with embryonic stem cells; the problem is that most of the stem c..." The scaffolds can be further modified by adding embryonic stem cells during polymerization, a process where small molecules are combined together to form larg...... division and differentiation, immune response and embryonic development. They also control the development and spread of cancer cells, and some, including RA, can inhibit tumor growth by preventing cancer cell proliferation. Retinoids are now in clinical trials for treatment of head, neck and breast cancers, ...