Tag: "engineered" at medical news

Studying smallpox without smallpox

...ate new therapies.. Rosengards group molecularly engineered SPICE by an indirect method, which did not require the virus. They used the DNA from the homologous vaccinia protein, VCP, as a template and changed 13 nucleotides to match the SPICE sequence, which had been published 8 years ago. This allowed them...

New wireless imaging test identified the cause of gastrointestinal bleeding in majority of patients

...ed by Given Imaging, Ltd.), on the other hand, was engineered to view most of the GI tract via a wireless endoscopic approach. About the size of a large megavitamin, the capsule contains a camera, light source, radio transmitter and battery and works by transmitting pictures of the small intestine to a wireles...

NIAID teams with Wyeth on HIV/AIDS vaccine

... Dr. Rose and his colleagues created a genetically engineered form of a virus called vesicular stomatitis virus ... which can cause a mild disease in livestock. The engineered virus contains only two HIV genes-not the entire virus-so it cannot cause HIV infection or disease. ...

Blocking adhesion protein may reduce lung damage from radiation

...ation of the lungs are reduced in mice genetically engineered to lack a protein called intercellular adhesion mo...ed in radiation-treated mice that were genetically engineered to lack ICAM-1, a cell adhesion molecule that mediates the recruitment of leukocytes, or white blood...

Blocking gene may reduce lung scarring caused by radiation therapy

... confirmed those findings in "gene knock-out mice" engineered to lack the gene, known as intracellular adhesion molecule (ICAM1). "If you eliminate ICAM1, you eliminate the inflammatory response," Hallahan said. So the next question to be addressed was whether the initial inflammation was the cause of the subse...

Special cell prevents diabetes in mouse model, report University of Pittsburgh researchers

...ntial clinical therapy that involves a genetically engineered version of these cells, they reported at the American Transplant Congress (ATC), Transplant 2002, at the Marriott Wardman Park Hotel in Washington, D.C. In diabetes, a patient's own immune system T cells invade and destroy the body's insulin- produci...

MMP enzymes play key role in stability and breakdown of atherosclerotic plaques

...has developed an experimental model of genetically engineered mice to study how atherosclerotic plaque forms. Through different kinds of cell surface markers, she can distinguish between circulating inflammatory cells and those already present in the arterial wall. Using this model, Dr. Galis and her colleagu...

Post-genomic technique provides real-time, multiscale look at protein life cycles in living cells

...ing cells to quickly reach the protein genetically engineered to contain the small binding domain. Then, upon binding, the compounds turn brightly fluorescent. FlAsH fluoresces green, whereas ReAsH glows red. To distinguish old from new proteins, the researchers first used the green FlAsH. Then, they applie...

Scientific society offers development sessions for industrial members

...s Council, Troy, Mich. Polymer trends: the role of engineered plastics in the automotive industry Monday, April 8, 12:30 p.m. This presentation will explain how and why plastics are currently used in vehicles to save weight, reduce fuel consumption and lower costs for motorists and manufacturers. The future of ...

Estrogen's role in preventing female cardiac disease

... been partly explained by studies with genetically engineered mice, according to researchers at Cornell and Vand...es, they say, are clear: o Among mice genetically engineered for a predisposition to an enlarged heart muscle, male mice develop early signs of cardiac hypertrop...

New study in mice shows promise for vaccine to prevent plaque buildup

...l vaccine to prevent plaque buildup in genetically engineered mice with high cholesterol levels. Abstracts of their results are being presented from 3 to 5 p.m. Monday, March 18 at the American College of Cardiologys annual scientific session in Atlanta. The vaccine consists of synthetic peptides (compounds t...

Cedars-Sinai researchers to present findings at Amerian College of Cardiology Scientific Meeting

...l vaccine to prevent plaque buildup in genetically engineered mice with high cholesterol levels. Abstracts of their results are being presented from 3 to 5 p.m. Monday, March 18 at the American College of Cardiologys annual scientific session in Atlanta. SOY AND ISOFLAVONES FOR PRIMARY PREVENTION (COMPLEMENTAR...

Two viruses team up in West Nile vaccine

...ch does not target the central nervous system, the engineered virus does not infect the brain. Second, the addition of select WNV genes causes the hybrid to stimulate strong anti-WNV immune responses, even following a single dose of the vaccine. When injected into mice, the vaccine protected all of the immuni...

Novel colorectal cancer trial seeking patient volunteers at leading U.S. cancer centers

...ered via a live recombinant canarypox virus vector engineered to elicit specific immune responses for cancer immunotherapy. Alvac is a variant of the canarypox virus that produces a self-limiting infection that does not cause any harm or symptoms in humans, but causes infected cells to temporarily display tumo...

The gene is out of the bottle: Where to next?

...d as we prepare for this next round of genetically engineered products. Panelists: * Charles B. (Ben) Beard, Ph.D., Centers for Disease Control and Prevention * Bruce M. Chassy, Ph.D., University of Illinois at Urbana-Champaign * Anne Kapuscinski, Ph.D., University of Minnesota * Doreen Stabinski, Ph.D.,...

From preventing disease to softening our ride, Virginia Tech inventions and creations can improve lives

...apsulated organisms." The vaccine is a genetically engineered bacteria with genes, necessary for the bacteria to survive and cause disease, removed. When the altered bacteria are injected into the muscle, they induce an immune response against bacteria that can cause disease. Ward now works for Johnson & Johnso...

Enzyme could provide continual fat burning

...at in development. "However, the mice genetically engineered to lack ACC2 seem very happy, live and breed well,... red, virtually fat-free livers of the genetically engineered animals. In one study, the researchers gave the ACC2-deficient mice insulin, which is produced in r...

Aspirin and other non-specific COX inhibitors may slow atherosclerosis

...he drug for long periods. Using mice that had been engineered to produce high levels of cholesterol, the scientists injected one group with the non-specific inhibitor indomethacin, a second group with the COX-2 blocker nimesulide, and a third control group with a placebo. Analyzing the mices aortas at the concl...

Pacific Northwest National Laboratory wins three R&D 100 awards

...sure the safety of food and may replace glass with engineered plastics in electronic display panels. Each y...ustry. Without these products -- Flexible GlassTM engineered substrates and BarixTM -- coating even the moisture in the air would cause sensitive Organic Light E...

Experimental drug reverses effects of Fabry disease in mice

...ves regular intravenous infusions of a genetically engineered form of the missing enzyme called recombinant beta-glucosidase," Shayman says. "It costs more than $200,000 for one year's treatment and currently is the most expensive drug on the market."...

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