New therapeutic approach for sickle cell disease
...isorder in humans characterized by chronic anemia, episodes of severe pain, and premature death. It is caused by an error in one of the genes that produces hemoglobin, an iron-protein component contained within the red blood cells that carry oxygen to body tissues. The defective gene directs production of abn...Depressed moms want pediatricians to hear them
...latively mild cases of the blues or incapacitating episodes of major depression, pediatricians can and should play a key role in keeping these women from slipping through the cracks. "Despite the fact that mothers want to turn to their pediatricians to talk about stress and depression, they fear being judged...Depression can lead to back pain
...sively when they experience the kinds of mild pain episodes that most of us are periodically subject to. This in turn may increase the likelihood that pain will become a problem in someone's life. The next step is to answer this question," added Carroll, whose research is sponsored by the Alberta Heritage Fou...Pitt receives $14.5 million from NIH to improve pediatric heart transplantation outcomes
...ons indicated significantly fewer "late" rejection episodes and less immunosuppression requirements one to five years after the procedure compared to 23 patients who did not receive donor bone marrow. Through the grant, these patients will continue to be followed and a second group of patients will be enrolle...Evidence that memories are consolidated during sleep
...d probably amplification of memory traces. Ensuing episodes of REM sleep, which are very short, trigger the expression of genes to store what was processed during slow-wave sleep." In principle, this model explains studies such as those by Robert Stickgold and his colleagues at Harvard University, showing tha...New method of distinguishing Alzheimer's from Lewy body dementia
.... In the study, Dr. Ferman and colleagues examined episodes of fluctuation in cognition (problems in thinking ...of DLB that comprise fluctuating cognition include episodes of confusion, excessive sleepiness, a waxing and waning of cognition, inattention, incoherent speech...Inadequate water and sanitation adversely effects child growth
...d sanitation were found to be shorter and had more episodes of diarrhea, according to research from the Johns Hopkins Bloomberg School of Public Health and other institutions. Past studies have shown that improvements to water supply and sanitation benefit health and improve life expectancy in industrialized ...Water and sanitation key to health of infants in developing countries
...ren) were 1 cm shorter and had 54% more diarrhoeal episodes than children with the best conditions (58 childre...hich were often uncovered) had 28% more diarrhoeal episodes than children from households with large containers. Lack of adequate sewage disposal explained a he...American Thoracic Society Journal news tips for January 2004 (first issue)
...up, 94 infants (39.5 percent) experienced wheezing episodes in their first year. Of these, 41 babies (17.21 percent) had recurrent wheezing. The investigators said that the odds of developing recurrent wheezing were 4.5 times higher in those in the lowest quartile of interferon gamma production at 3 months ...Genomics research: New genetic 'hit list' may underlie susceptibility to sudden cardiac death
...olving the heart's electrical system and can cause episodes of fainting, seizing or sudden death. Its presence can often be detected with an electrocardiogram (ECG) where the interval between points Q and T is abnormally prolonged. If untreated, half the people with symptomatic long QT syndrome will die withi...American Thoracic Society Journal news tips for December 2003 (second issue)
...olisms could be averted at the expense of 14 major episodes of gastrointestinal bleeding and 13 episodes of heparin-induced thrombocytopenia for every 10,000 ultrasound tests performed. The study is publ...Passive tobacco smoke increases complications in children with sickle cell disease
... peripheral tissues. These abnormalities can cause episodes of severe pain, known as sickle cell crises, and life-threatening damage to vital organs, such as the lungs and the brain. Over a period of two years, researchers monitored 52 patients between the ages of 2 and 18 with several types of sickle cel...Security duties damage soldiers' mental health
...g periods of inactivity interspersed with sporadic episodes of exposure to potentially dangerous situations. Future research should explore what aspects of a soldier's existence contribute to changes in psychological illness if remedial steps are to be taken to maximise a soldier's professional potential, th...Solitary pancreas transplant not associated with improved survival for patients with diabetes
...d severe and frequent metabolic instability, i.e., episodes of very low blood glucose levels (hypoglycemia) or high blood glucose levels with buildup of blood acids (ketoacidosis). According to the article, solitary pancreas transplantation (i.e., pancreas alone or pancreas-after-kidney) for diabetes mellitus...Air pollutants alone may cause asthma attacks
...he small airways in the lung and can trigger acute episodes of airway tightening and wheezing. Researchers first gave mice a surrogate allergen, which would be similar to exposing humans to an allergen such as pollen. After several days, researchers administered aerosolized diesel particles to the mice, simul...Study shows Joslin's 'Care Ambassador' program helps kids with diabetes better manage the disease
...hoeducational materials had 25 to 60 percent fewer episodes of hypoglycemia (low blood sugar). In addition, hospitalization and trips to the emergency room were reduced by 40 percent. When translated to the high cost of diabetes and its complications, the researchers speculated that for every 200 youth with t...New drug-and-psychotherapy program for bipolar disorder in children
...stating mood disturbance, characterized by cycling episodes of mania and depression, irritability and aggression, inflated self-esteem and grandiosity, decreased need for sleep, constant talking and activity and even psychosis. In children, it is associated with an alarming rate of suicide, failure in school,...Repeated alcohol detoxifications can impair cognitive function
... likely to have seizures if they have had previous episodes of detoxification. New research confirms that rep...xperience seizures if they have undergone previous episodes of detoxification. Prior research has also indicated that multiple withdrawals may lead to changes ...Astrazeneca receives European approval for Seroquel; in bipolar mania
...lent first line therapy for the treatment of manic episodes associated with bipolar disorder. Individual licenses in the 14 European countries involved in the MRP will follow from the completion of this procedure. Health Authority approvals have also been received in Mexico and New Zealand. "We believe th...White blood cell plays key role in body's excessive repair response to asthma
...he airways, resulting in worse and repeated asthma episodes for sufferers. The team of scientists from Imperial College London, the Royal Brompton Hospital, London, Guys Hospital, London, McGill University Hospital Centre, Montreal, and St Barts and the Royal London Hospitals Trust, report that the damaging e...