Hormone therapy for breast cancer - the treatments of the future
...rs, anastrazole (Arimidex), letrozole (Femara) and exemestane (Aromasin), can achieve almost complete oestrogen shutdown. Recent findings indicate that this is why the new aromatase inhibitors are proving even more effective than tamoxifen, a selective oestrogen modulator or SERM. Although tamoxifen acts largel...Exemestane shows high tumor response rate in first-line treatment of advanced breast cancer
...nals of Oncology (vol. 14, issue 9) indicated that exemestane demonstrates a high response rate for first-line t...ical study, 122 patients were randomized to either exemestane (25 mg/day) or tamoxifen (20 mg/day). The results indicate that exemestane was well-tolerated. Wome...Exemestane beats tamoxifen in first phase III head to head trial in advanced breast cancer
...compare tamoxifen with the newer hormone treatment exemestane in advanced breast cancer shows that exemestane is safe, superior and lengthens progression-free survival. The median progression-free survival for ...New study reveals big disparity between countries in breast conservation rates
...ostoperative tamoxifen vs sequential tamoxifen and exemestane in postmenopausal women with operable breast cancer. The surgery involved was dependent on tumour characteristics, but otherwise had been left to the discretion of the investigators, and all curative surgical procedures had been allowed. To reduce th...Updated adjuvant data presented at SABCS show 30 percent reduction in recurrence
... These findings showed that 193 women treated with exemestane experienced a local or distant recurrence of disea...South America. Unlike other aromatase inhibitors, exemestane is a steroidal aromatase inactivator, which means it selectively targets and irreversibly binds to t...International breast cancer prevention study launches in the United States and Canada
...search study will examine the potential benefit of exemestane and its ability to prevent breast cancer in women ... New England Journal of Medicine demonstrated that exemestane can prevent the occurrence of new cancers in the opposite breast of women who have already had breas...