Raloxifene following tamoxifen may offer no more reduction in breast cancer risk
... may not be beneficial. O'Regan and her colleagues exposed breast and endometrial tumors in mice to combinati...her prevent the growth of breast tumors previously exposed to more than 5 years of tamoxifen. Furthermore, raloxifene did not block the growth of endometrial t...Raloxifene after tamoxifen not beneficial
...further prevent growth of breast tumors previously exposed to more than five years of tamoxifen. Moreover, raloxifene was less effective than tamoxifen in blocking the growth of endometrial tumors caused by low-dose estrogen. Tamoxifen is a selective estrogen receptor modulator (SERM) that reduces breast ...Chemical attraction needed to launch an immune attack
...e to being pulled toward the T zone after they are exposed to the antigen. While the mechanism is clear and convincing, other factors, such as adhesion molecules, may also play a role the researchers suggest. Cell migration is critical not only in the adult immune defense, but in all phases of embryonic deve...Air pollution causes healthy blood vessels to constrict
...e. Their vessels did not constrict when they were exposed to ozone-free and particle-free air. We have a wea...bjects underwent the same measurements after being exposed to air that was filtered to remove the pollutants. The volunteers arteries showed no change in respo...Immune system in hamsters bolstered during winter, especially in times of stress, study finds
...ificial light, the researchers exposed half of them to long days (15 hours of light per day) to simulate summer conditions. The other half lived in short days (9 hours of light per day) to simulate winter conditions. ...Depressed teens receptive to tobacco advertising more likely to experiment with smoking
... cigarette. The data show that adolescents who are exposed to peer smoking are more likely to smoke themselves. Furthermore, adolescents who are highly receptive to tobacco advertising and have clinically significant symptoms of depression are also more likely to smoke than adolescents without these symptoms...Arsenic in well water related to atherosclerosis
...ughout the body. More than 100 million people are exposed to underground water with high concentrations of a...the risk of atherosclerosis as people who were not exposed to arsenic. Those in the mid-range of exposure had double the risk of someone who was not exposed. ...Hormone drug linked to increased prevalence of male genital disorder
...mon among boys born to mothers who were prenatally exposed to a synthetic hormone withdrawn in the late 1970s...l cancer and fertility disorders in women who were exposed to the drug prenatally. Flora Van Leeuwen and colleagues from The Netherlands Cancer Institute, Amst...Allergens and viruses act together to worsen asthma
...dmitted with asthma (66%) were both sensitised and exposed to allergen causing sensitisation (either mite, cat, or dog) than patients with stable asthma (37%) and inpatient controls (15%). Viruses were detected in 26% of patients admitted with asthma compared to 18% with stable asthma and 9% of inpatient con...Primate bushmeat : Populations exposed to simian immunodeficiency viruses
...e data document for the first time that humans are exposed to a plethora of genetically highly divergent viru... magnitude and variety of sivs to which humans are exposed to through contact with non-human primates. Nearly 800 monkeys , hunted in the rainforests, and su......e on them without further studies. "A person isn't exposed to just one chemical, but rather a mix of many," says Julia Brody, director of the Silent Spring Institute in Massachusetts, a non-profit organisation that looks at the environment and women's health. "There is an increasing awareness that hormonally...American Thoracic Society Journal news tips for April (first issue)
...diagnosed female asthmatics who were sensitizedand exposed to high levels of cat allergen in their living rooms. These individuals reported greater difficulty with asthma during the prior year, in addition to having wheezed more oftenwithout a cold. Over the four-year follow-up period, the affected persons...Agricultural fungicide could cause irreversible immune system damage
...st of the TPT levels that agricultural workers are exposed to in the field are probably below what her group ...lood samples of agricultural workers who have been exposed to TPT to see whether significant quantities of the compound can be measured in their blood. A type ...Genetic connection in link between permanent hair dye use and bladder cancer risk
...er cancer risk also was observed in people who are exposed to hair dyes in their work, such as barbers and hairdressers. Increased risk was not seen for those who used temporary or semi-permanent dyes. Gago-Dominguez explained that small amounts of arylamines are absorbed through the skin during the use of h...Magnetic fluids offer hope for damaged retinas
... silicone-based fluid (polydimethylsiloxane). When exposed to an external magnetic field, the fluid can be maneuvered in much the same way that magnetic pieces are moved around in certain toys, Riffle explains. The retina is the thin, light-sensitive layer of tissue located at the back of the eye. When it b...Children as young as 5 have gender bias when it comes to picking a musical instrument
.... Even when some of the children in the study were exposed to an intervention, boys were far more resistant to change their gender-based choices. "Girls become more flexible as they get older, but boys mostly pick masculine instruments. They just cannot pick a feminine instrument. It is so hard for them th...Cedars-sinai surgery dept. implements innovative surgical training tool to reduce medical errors
...surgeons. It has been shown that surgeons who are exposed to errors early in their careers are less likely to make them later. And this, according to Gordon, was the impetus for implementing the M & M Matrix educational model. In 1999, the national Institute of Medicine released To Err Is Human: Building ...Kaleidescope eyes: the secrets of a novel gift
...e is also activated in non-synaesthate people when exposed to tests that require a response inhibition. "Ultimately this research will help reveal how we bind perceptual information from all five senses, information that is normally processed in different parts of the brain," says Rich. "Synaesthetes provide...Brain-imaging study offers clues to inhalant abuse
...irsprays. "There isn't a person among us who isn't exposed to solvents," Dewey said. The Brookhaven team is already applying for grants to study other inhalants, first in animals and then in humans. They are also working to develop a method to study these chemicals in inhaled as well as injected form to furt...At 2 years, cocaine babies suffer cognitive development effects
...eight and small for gestational age infants in the exposed group. Researchers also found that the rate of men... of children with mild delays (37.6 percent in the exposed group v. 20.9 percent in the non-exposed group) requiring intervention was almost double the rate of...