Antioxidant-Enhancing Drug Partly Rescues Noise-Induced Hearing Loss
...ensory cells. To defend themselves, sensory cells express a rush ofglutathione, an antioxidant that absorbs free radicals. R-PIA was found toincrease the activity of glutathione, thus providing enhanced protection fromfree-radical damage. To test the effect of the drug on hearing loss, researchers ...Researchers Finding May Boost Effectiveness Of Anti-HIV Drugs
...inical Investigation. In cell cultures that express large quantities of Pgp, the VUMCresearchers found...to mice thathad been genetically engineered not to express Pgp, brain levels of the drugsclimbed to seven-to-40 times higher than in mice that normally express...... in Blacksburg, was the first to induce a plant to express an human protein with enzymatic activity. That achievement has opened the possibility of using plants as factories to produce human proteins that can be used in pharmaceuticals. The tobacco planted at Virginia Tech's agricultural research and exten...Substance Discovered That Induces Hair Follicle Formation In The Mature Skin Cells Of Mice
...ide-effects. "If we can find a way to transiently express beta-catenin in these skin cells, just until new follicles are established, and then turn it off, we may be able to prevent tumor formation and still allow hair follicles to form," says Fuchs. The flip side of this, she says, is that it is also a po...Program Developed At UF Enables Computer To "Emote" In Speech
...eople type in what they want to say, choose how to express it, then pressa "translate" button on the screen. The program conveys some emotions better than others, Truluck's testsshowed. Of 30 randomly selected volunteers who listened to sentences read by thecomputer, nearly all identified the...Temples Virtual Lab Helps Disabled Students
...r to pursue their master's degrees, leading Butzto express optimism that refinement of the project will continue. "All the pieces are lined up," he says. "Between us we have a unique blend ofexperience here. I'm very hopeful." Butz's team is creating a series of projects for IMITS to assign to students who...Neurobiologists Show How The Brain Processes Signals From Pheromones
...t, the researchers found that all the neurons that express the samepheromone receptor project their axons to multiple targets in the accessoryolfactory bulb, called glomeruli. There are about 15 glomeruli in all, comparedto only two in the main olfactory bulb. Second, the positions of the glomeruliin the ac...New Vaccine Provides Protection From HIV In Monkeys
...ch consisted of genes takenfrom a SHIV. The genes express specific SHIV proteins that help the bodyproduce a...1) DNA vaccines - segments of DNA that codefor and express the proteins from a microbe, thus allowing a vaccinated personto generate his own immunizing protein......he Mailman School of Public Healthsaid, "I want to express our deepest appreciation to the Gates Foundation forthis extraordinary opportunity to help women around the world. We are honoredby the trust that the Foundation has placed in us." Bill and Melinda Gates have endowed two foundations with $6....Biological Markers Found That Correlate To Esophageal Cancer Treatment Success
...ted compared to normalcells. In some cases tumors express genes that normal cells don=t, and inothers the tumors lack genes normally expressed. A third option is for a geneto be altered, or mutated, in a way that scientists can detect. All of thesechanges are reflected in the presence, lack, or mutation o...False recall in older adults and Alzheimer's linked to attention, not memory, breakdown
... St. Louis. It's no secret that older adults often express frustration at their increasinginability to recall seemingly simple things, but this study suggests that olderpeople -- and to a much greater extent those individualsstruggling with Alzheimer's -- should also be somewhat skeptical about theaccuracy o......up has developed astrain of "humanized" yeast that express the DNA of human enzymes. They plan touse yeast cells, converted into little versions of human adrenal glands, as ascientific model to study the action of the human enzymes that are involved insex steroid hormone production. Lee worked in the Miller ..."Baby check" information for parents does not affect frequency of contact with family doctors
... accurately. Both Dr Jewell and Drs Thomson et al express concern at the high level of antibiotic prescribing for babies under six months...13 lifelines successfully used in unique umbilical cord blood transplant into ailing adult
...ound in bone marrow, isnow being collected for the express purpose of treating serious diseases such asleukemia and other forms of cancer. The blood is then stored either privatelyfor future use by the family storing the blood, or in a public banking facility.In their three years of operation, CorCell has s...Engineering pits beneath London Underground tracks are helping to save lives
...all away from the train's wheels. Coats and Walter express concern that the new Jubilee line trains have less ground clearance, leaving less room for a body to escape the wheels. They also suggest that, expense aside, the most effective means of preventing deaths under trains would be to introduce sliding d...Mothers of chronically ill children often face depression
Mothers with chronically ill children frequently express dissatisfaction withtheir role as a parent and often display severe symptoms of depression, newresearch reveals. "The time demands that result from caring for a child with a health conditioncan limit a mother's opportunities to work or participate in...A new ion channel involved in cell proliferation: evidence for its oncogenic potential
... fact, severalcell lines derived from human tumors express the hEAG channel, whereas therespective normal tis... micecarrying tumors that have been manipulated to express EAG (Figure 2). Once cancer has established, many cell functions are altered and the expressionof ma...Estrogen-driven gene activates human pituitary tumors, Cedars-Sinai Medical Center researchers find
...nce in tumor development. In men, pituitary tumors express excess estrogen receptors. Awaiting publication is an important related discovery that PTTG is expressed in other forms of cancer, and that estrogen is linked to its insidious trigger of malignant cell growth in those organs as well. Now researchers ...Scientists develop transgenic mouse that models Parkinson's, related disorders
... in the Feb. 18 issue of Science that mice bred to express a human protein called alpha-synuclein in the brain develop protein deposits in specific brain regions associated with Parkinson's disease, and also have impaired motor function. "Previous studies have shown increased levels of this protein in the br...Establishing "stroke centers" in hospitals would reduce deaths and disabilities, say stroke experts
... attached fact sheet. In the article, the authors express their hope that the adoption of these recommendations will increase the use of appropriate diagnostic and therapeutic tools and reduce complications from stroke. "These recommendations are a perfect example of what the Brain Attack Coalition came tog...