Diabetes may be going unnoticed in many UK children
...eport them. We must be sure that, when children do express discomfort in some form, we listen to them. There are high costs associated with missing a case of diabetes through lack of attention, ignorance, or unconscious discrimination against overweight children," they conclude....Researchers develop better understanding of tamoxifen resistance in breast cancer patients
...rs that might be expected to respond (because they express receptors for estrogen) are resistant to antiestrogens from the onset of treatment, and many initially responsive tumors sooner or later become resistant. The Lombardi researchers studied a series of antiestrogen-sensitive and antiestrogen-resista...Siblings help children get along with others in kindergarten
...ho are different, comfort and help other children, express feelings in a positive way, and show sensitivity to the feelings of others. "Children without siblings were consistently rated as having poorer social skills," said Douglas Downey, co-author of the study and associate professor of sociology a...Emselex(R) receives positive CHMP opinion for the treatment of overactive bladder
...potential", "may be" or similar expressions, or by express or implied discussions regarding potential marketing approvals or future sales of Emselex . Such forward looking statements reflect the current views of the Company regarding future events, and involve known and unknown risks, uncertainties and othe...Lab studies show two proteins prevented progressive nerve cell loss in Parkinson's disease
...e, has been genetically manipulated to selectively express proteins that can protect the neurons that are damaged during the course of Parkinson's disease. "Currently, we are constructing other versions of this virus that could eventually be used in clinical trials in humans that are safe even when the body ...News tips from the Journal of Neuroscience
...ical progenitor cells, and the progenitors in turn express temporally regulated Pea3 transcription factors. Thus, the elusive "environmental factors" present in the ventricular zone get a name. ...Problematic behaviour of dementing patients exacerbated
...If they cannot accept the behavioural problems and express this irritation towards the dementing patient then the patient can become more restless. During her doctoral research, De Vugt identified three strategies that care-providing family members adopt to approach the dementing patient. The 'supportive str...Family therapy reduces stress symptoms in adolescent survivors of childhood cancer
...othersome memories about the child's cancer and to express personal beliefs about the adverse experiences. Therapists then taught the participants coping skills by encouraging them to reframe their thoughts to focus on controllable and positive consequences. "We might urge a survivor to say, for example, 'C...Radiotherapy + cetuximab significantly improve disease control and survival in head and neck cancer
...ll head and neck cancers and the majority of these express the epidermal growth factor receptor (EGFR) that is associated with aggressive tumour growth and poor clinical outcome. Head and neck cancer is normally treated with high dose radiotherapy in combination with surgery. These phase III results were bas...New finding could make addiction treatment more effective
...l had a fourfold increase in one of the genes that express the calcium channels, compared to animals that didn't consume alcohol. "The alcohol suppresses the calcium channels, so the cells in the thalamus may compensate by making more copies of the gene," said Godwin. "However, this overproduction of t...Engineered stem cells can home in on tumors and deliver drug payload in mice
...ndreeff. The team tested whether MSC engineered to express an interferon beta gene could provide a sustained ...hree weekly doses of intravenous MSC engineered to express the interferon beta payload. They found that the MSC cellular vehicles readily grafted thems...Marine sponge leads researchers to immune system regulator
...ize some bacterial lipids. At the same time, they express less-variable versions of T-cell receptors. These stripped-down receptors enable NKT cells to respond to a limited array of lipid or carbohydrate antigens when presented in certain ways. The only substance known to fully activate NKT cells through t...Top 10 toys for children with ADHD
...uffed animals or action figures allows children to express feelings that they might not otherwise be able to ...markers, or paints give children an opportunity to express themselves in a non-verbal way. There is no right or wrong way to use these art supplies. As a par...New protein 'stop sign' alters blood vessel growth
...ck. Results of the studies, published today in the express online edition of Science, are of special interest to researchers trying to prevent blood flow that nourishes tumors or exploit the signals vessels emit during growth to help regrow damaged nerves. During an animal's prenatal development, protein "s...Mayo Clinic discovers potential marker for aggressive kidney cancer
...e at the clinical level to demonstrate tumors that express B7-H1 are aggressive, so there's been no way to pr...ated at Mayo Clinic. They found that when patients express this molecule on their kidney cancer cells, they are at markedly increased risk both of the cancer s...Imatinib (Gleevec) has activity in AIDS-related Kaposi's sarcoma
...that the drug is also active in other cancers that express some of the same proteins," said Henry B. Koon, MD, Instructor of Medicine, Beth Israel Deaconess Medical Center/Harvard Medical School in Boston, and lead author of the study. "Studies like this one represent an exciting time in oncology, when our u...Stem cells of limited use for cardiac muscle repair
... muscle function. The failure of these cells to express this protein "severely limits their utility for cardiac and skeletal muscle regeneration," the authors note. "This was a complete surprise, and a considerable disappointment," said study director Elizabeth McNally, M.D., Ph.D., associate professor...Lab study: Protein delivered via genetically engineered virus slowed glioblasoma multiforme growth
...at had been genetically manipulated to selectively express hsFlt3L to find out if it would increase the number of dendritic cells in the brain of laboratory rats with GBM. To evaluate whether hsFlt3L could shrink brain tumors and prolong survival, rats with GBM were injected with increasing doses of...Research gets to heart of advertising gender bias
...ence and severity of heart disease among women and express concern that their findings also mirror the medical literature. "While efforts to increase female representation in cardiovascular trials are ongoing, the vast majority of scientific evidence is based on men," says Cheung. This study appears in th...Cell marker identifies patients who are more likely to respond to taxol
...ose breast cancer cells have lost their ability to express a protein called "tau" are twice as likely to have a good response to Taxol treatment, the researchers report at the annual San Antonio Breast Cancer Symposium meeting. The finding makes sense because tau promotes the assembly of microtubules, which ...