Discovery Hints At Multitude Of New Targets For Drugs
...armacology in the Duke medical center. The finding extends earlier work in his laboratory showing that the estrogenreceptor, a distinctly different kind of steroid receptor, also shows similarmulitple modes of interaction with drugs or hormones. "The discovery of such complexity in one receptor typ...Duke Obtains FDA Designation For Pompe Disease Therapy
...irst appearlater in childhood, but life expectancy extends only into the second orthird decade in such cases. Adults can be affected by a milder form of thedisease but are still incapacitated due to respiratory insufficiency. Initially, the therapy developed at Duke will be tested in infants withthe most se...MIT Solution To Math Problem Could Lead To Better Dental Implants, More Resistance To Missiles
... probe used to poke the material isso tiny that it extends into only one section of a graded material. "So youcan't generalize to cover the rest of the material," Professor Suresh explained.At the other extreme, the probe of a macroindentor is too big to capture thedetails of the gradient. "We needed somethi...First Trimester Screening For Down Syndrome Possible, NICHD-Funded Study Finds
...s well as human chorionicgonadotropin. This study extends screening to the first trimester. Women with abnormal levels of these substances are usually then referredfor diagnosis by amniocentesis. For the study, Dr. Haddow and his coworkerscollected blood samples from a total of 4,412 pregnant w...Crystal Structure Of gp120 Reveals HIV In Action
... Having the structure of gp120 complements and extends the fuzziersnapshots of the molecule from genetic studies. "We can use mutational analysisto say 'the CD4 binding site must be here.' But with X-ray crystallography, weactually see it," explains Dr. Hendrickson. And what they see in the structureis w...Reduced Heart Disease Risk In Middle Age Lowers Eventual Medicare Costs
...iddle age not onlyimproves health in older age and extends lifespan -- it is also better for thenation's fiscal well-being. A study by Northwestern University Medical School researchers foundsignificantly lower Medicare health costs in older people who had no heartdisease risk factors, such as high c...First Drug Shown Effective For Treating Chronic Forms Of Major Depression
...aline protects againstrecurrence and greatly extends remission time. The drug is currently not indicated foruse in the treatment of chronic depression. Previous research has shown sertralineto be effective in preventing relapse in patients suffering non-chronicepisodes of major depres...Best Use Of Angiostatin May Be To Enhance Radiation Therapy
...thout same-day radiation therapy. "This study extends our previous finding that angiostatin becomes muchmore effective when used to enhance the effects of radiation," saidWeichselbaum,"and that radiation, already a standard of cancer therapy, could becomemore effective with a boost from short courses of...Fetal Cell Therapy Benefits Some Parkinson's Patients
...n on use offederal funds for human embryo research extends only to studies in which a humanembryo is created for research purposes or is subjected to risks greater thanthose allowed for fetuses in utero. In addition to Dr. Freed and his colleague Robert Breeze, M.D., at theUniversity of Colorado, the researc...Early stroke treatment with t-PA has long-lasting benefit, according to NEJM report
...ts?" the group reports. The current study extends to one year the group?s 1995 findings of asustained three-month benefit from early t-PA treatment. The study populationwas comprised of 624 ischemic stroke patients randomly assigned to receiveeither t-PA or placebo intravenously in the emergency dep...UCSF Cancer Center joins elite group of National Cancer Institute-designated centers
...4 million. But the significance of the designation extends beyond funding, UCSF officialssay. It will help turn UCSF into a major player in the "war against cancer" byincreasing treatment and research opportunities for patients and scientists. Thedesignation also will help to attract more world-class scienti...'Plug and patch' method of hernia repair an effective replacement for old surgical methods
...hesia and involves a deeper surgical approach that extends into theabdominal cavity, according to Millikan. The alternative laproscopic method isalso approximately twice as costly as the plug and patch method. Earlier hernia repair methods, which are still used, involve stitching togetherthe two sides of the...University Of Wisconsin to launch center to study how emotions affect health
...forts to anew order of magnitude." The center also extends several ongoing campus collaborations that have beennurtured by MacArthur Research Networks, which includes Davidson along withinvestigators Nadine Marks, Carol Ryff and Burton Singer. "What made our proposal unique relative to others around the coun...New mathematical model explains changing patterns in epidemics
...ns, Bolker said. "The possibility for prediction extends beyond diseases to other predator-prey cycles," Bolker said. In October, the same team of researchers published a paper in Science that reported on radically different effects of immunization programs on measles and whooping cough epidemics....New grants program to help create healing environments in hospitals through art
... the will to live and infused me with a peace that extends far beyond my own comprehension." This kind of reaction has spurred outside funding such as the Society's new grant. As NEA chair Bill Ivey said at a recent Department of Health and Human Services meeting in Washington, DC, "The beginning of the new ......y and 10MIU/m2 subcutaneously), interferon alfa 2b extends overall survival in surgically treated patients, as well as relapse-free survival, or the amount of time free of disease recurrence. Patients who received the GMK vaccine, by contrast, showed significantly lower overall survival and relapse-free surv...UNC-CH School of Social Work receives grant to prevent violence
...c and behavioral problems," said Fraser. The grant extends work that the researchers have done with the state and Winston-Salem's Z. Smith Reynolds Foundation, in which they developed strong ties with Dr. Larry Mabe, superintendent of Chatham County Public Schools and Susan Eckblad and Randy Johnson, princip...Patent rights stimulate R&D, but fall short in helping poor countries obtain lifesaving drugs
...rom other countries. Patent protection under TRIPS extends for a minimum of 20 years. Prior to the agreement, WTO-affiliated countries were able to produce cheap copies of drugs and other pharmaceutical products because they were under no obligation to meet the same standard of intellectual property rights ...Statement by Dr. Colwell on Nobel Prizes in Science and NSF onnection
... The impact of the Nobelists and their NSF support extends beyond the research itself, into the network of people who support or benefit from it. Most of the laureates serve regularly as reviewers of NSF proposals. All three physicists play key roles in NSF-funded centers which integrate various groups beh...Robotic physical therapy improves movement long after stroke
...bot, designed to stand on a table, has an arm that extends for about two feet. The patients affected arm is secured into a supportive arm trough that is attached to the end of the robots arm. Once the patients arm is secured, the robot moves the arm, working the patient through a series of programmed motio...