Tag: "faulty" at medical news

NYU'S Duster cautions against FDA approval of 'race-based' pharmaceutical

...l to combat heart disease among blacks is based on faulty research and urges the Food and Drug Administration to obtain more reliable data before approving the drug. Duster, president of the American Sociological Association, writes that research on isosorbide dinitrate and hydralazine (BiDil), produced by ...

Abnormal brain activity during the observation of others' actions

...non-autistic individuals. The work suggests that a faulty mirror-neuron system could represent the neural underpinnings of the social deficits characteristic of autism, alterations that ultimately lead to reduced reciprocal social abilities and perhaps prevent the normal development of empathy....

Fred Hutchinson receives $9.7 million to lead early detection consortium

...oteins that signal genetic defects associated with faulty DNA repair. Women who harbor such genetic mutations would be good candidates to receive more intensive screening for breast cancer. Project co-investigator Christopher Kemp, Ph.D., an associate member of Fred Hutchinson's Human Biology and Public He...

Scientists align billion-year-old protein with embryonic heart defects

...scular disorders, and perhaps a way to replace the faulty genes through targeted therapy. Scientists studying a vital protein called Serum Response Factor (SRF) in mice have learned new and unexpected facts about SRF's role in early cardiovascular development, and how a defect in this gene may b...

'Fatally flawed' legal analysis will not stand

...Alliance for Taxpayer Access quickly dismissed the faulty analysis made by the American Physiological Society's outside counsel suggesting the National Institutes of Health's public access plan will infringe copyright claims of grantees and publishers. [The claims were included in the APS comments filed wi...

Vaccine preparedness, or not

...lf this year's stocks were impounded. The risk (of faulty batches) should be spread across several manufacturers. The UK hedged its bets and thus secured supplies. It will not look good if US campaigns for influenza vaccination have to overwrite their adverts this year with the addition of ". . . If you c...

LSUHSC neurosurgical team discovers novel therapy for intractable hiccups

...ping around the vagus nerve in the neck to disrupt faulty nerve communication. The "dose" of stimulation, programmed by the physician, is automatically delivered. VNS therapy has been effective in controlling medically refractory seizures, and an FDA Advisory panel recently recommended approval of VNS thera...

Tumor suppressor gene family may be key to new colon cancer drugs

...lerator," explains Velculescu. "In this case, the faulty brakes are mutated tyrosine phosphatases and the accelerators are the tyrosine kinases." Tyrosine kinases have been of critical value in the success of such cancer-fighting drugs as Gleevec, Iressa and Herceptin, which block proteins made by tyrosin...

Alzheimer's pathology reduced, longevity improved in mouse model, Gladstone study shows

...is like electrical circuits in a computer becoming faulty -- signals can no longer be transmitted through broken connections," says senior author and GIND director Lennart Mucke, MD, who is also Joseph B. Martin Distinguished Professor of Neuroscience at the University of California, San Francisco. "Our res...

NIH launches study of hematopoietic stem cell transplantation for severe, treatment-resistant lupus

...ing for cell properties that may contribute to the faulty immune response found in lupus. B cell studies will be conducted by scientists at NIAMS, while T cell studies will be conducted by scientists at NCI. Researchers at the National Institute of Neurological Disorders and Stroke and the National Institut...

Cancer gene therapy news backgrounder: New ideas fuel next generation gene therapy research

...rm cancer. Such treatment would replace missing or faulty genes that keep cell growth in check, or would flush the body with "super genes" that could attack and destroy cancer. But as yet no such "gene therapy" for cancer has ever been approved by the United States Food and Drug Administration (FDA). Past ...

Successful therapy for head and neck cancer may lead to long-term circulatory problems

...diation generates toxic free radicals and leads to faulty repair of DNA breaks and cell death. Responses to radiotherapy occur in time frames of hours (nausea, vomiting), days (erythema), weeks (bone marrow supression), months (fibrosis), and years (carcinogenesis). Among survivors of the cancer itself, lat...

Not guilty! Evidence exonerates 328, but many still falsely imprisoned

...r of false convictions based on different types of faulty information. For instance, convictions based on false confessions could be greatly reduced by videotaping police interrogations so that judges and juries can see for themselves the circumstances that led the defendant to confess. Another key finding ...

Key to proper blood vessel growth in eye and ear discovered

...the developing eye to branch into capillaries. The faulty versions found in people, however, don't interact ... an earlier study of mice missing Norrin, which is faulty in Norrie [sic] disease. Both diseases are characterized by problems in blood vessel development in ...

UCSF physicians publish groundbreaking book on medical mistakes

...mergency room. "Through these cases, we argue that faulty systems, rather than bad people, are responsible for most medical errors, and that fixing this epidemic will take new resources, approaches, culture, and training," said Wachter. "The cases are less horror stories of malfeasance or incompetence than ...

Combination, order of anti-HIV drugs make a difference in first-time recipients

...T inhibitors, which halt HIV replication by making faulty DNA building blocks, and non-nucleoside inhibitors, which bind to the enzyme reverse transcriptase to prevent the virus from copying itself. The effectiveness of different drug combinations may diminish over time, however, and physicians often must i...

Scientists map maturation of the human brain

...ism, an early onset disorder, may occur because of faulty development early on. Childhood onset schizophrenia, with a somewhat later onset than autism, shows a back to front wave of gray matter loss, whereas later onset (the more typical form) schizophrenia seems to be more strongly associated with later ma...

Mayo Clinic researchers discover genetic syndrome linked to inherited birth disorder

...nd thymus gland, or heart defects. Other symptoms: faulty immune function and degrees of mental impairment. The Significance of the Mayo Clinic Research The work is important from the perspectives of genetic counseling, patient care and the history of medicine. The risk of inheriting this syndrome is 50 p...

Gastric bypass surgery for obesity may ease symptoms of gastroesophageal reflux disease

...tomach acid spills into the esophagus because of a faulty valve at the bottom of the esophagus. The result i... blockers. When these fail, surgery to correct the faulty valve remains the only option. The study enrolled 152 patients who met the criteria for GERD, had da...

Heavy drinkers seem to get a bigger 'bang' from alcohol than do light drinkers

...like driving a car with a powerful engine but with faulty brakes. It is fun to drive, but may eventually get you into trouble." Anton believes these kinds of findings can help scientists and doctors predict the development of future alcohol problems by evaluating an individual's current response to alcohol...

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