Tag: "fibrils" at medical news
Renal amyloidosis worsens the Familial Mediterranean Fever prognosis
...and fatal disease marked by the deposit of amyloid fibrils
in the kidney. When caused by an inflammatory disease such as FMF the deposited fibrillar material is of the Amyloid A (AA) type and the condition in this instance is known as AA amyloidosis. AA amyloidosis can be caused by a number of chronic inflam...
Carnegie Mellon uses AFM to discover effects of experimental drugs on Alzheimer's plaques
...ent protein, the A peptide readily aggregates into fibrils
that are rich in insoluble stacked structures called beta sheets. These fibrils
then congeal into tangled plaques. For the past few years, scientists in the field have been focusin...
Two proteins may help prevent Alzheimer's brain plaques
...le to dissolve or be cleared out of the brain, the fibrils
eventually clump together and become the amyloid p...eposits. However, the opposite was true. Moreover, fibrils
in animals lacking both proteins developed significantly earlier in life and resulted in the more ad...
A new hypothesis about Alzheimer's disease
...er's disease, because they can accumulate into the fibrils
and plaques that autopsies reveal in the brains of patients with the disease. These fibrils
and plaques and their precursors are implicated in neuronal loss. The inflammation process that cre...
Computer simulation shows how fibrils form
...t how proteins gather into clusters called amyloid fibrils
which are associated with important human disease... of layered protein sheets, similar to the amyloid fibrils
discovered in diseased people and animals. Hall says that understanding how fibrils
form in human or...
Antibiotic rifampicin shows promise for fighting Parkinson's disease in lab tests
...tuberculosis, can prevent the formation of protein fibrils
associated with the death of brain cells in people...kinson's disease. The drug also dissolved existing fibrils
in laboratory tests. The researchers studied the effects of rifampicin in test tube experiments and...