UI researchers find way to possibly improve effectiveness of gene transfers
... this means delivering a normal copy of the cystic fibrosis gene to cells lining the bronchial airways. However, researchers have had difficulty getting the vectors to stick to the cells. "The major problem is that the viruses we use to carry in a gene don't bind very well to the airway cells," Welsh said. "T...Researchers discover potential new approach to treating cystic fibrosis
... To date, research on treatments for cystic fibrosis has focused on geneand protein therapies and antib...mal model," said PeterDurie MD, director of cystic fibrosis research at The Hospital for Sick Childrenin Toronto, where the cystic fibrosis gene was discovered ...UI study advances understanding of antimicrobials and cystic fibrosis-related infection
...oncentrations in the airways of people with cystic fibrosis prevent theseantimicrobial factors from working ef...arch scientist and principal investigator. Cystic fibrosis is the most common fatal inherited disease among Caucasians ofNorthern European descent and occurs i...Chronically Ill Teens Turn To Internet For Peer Support, Researchers Report
...said teenagers withsuch chronic diseases as cystic fibrosis (CF) become socially isolated becauseof their symptoms or treatments, making it difficult to arrange traditional,in-person support groups to address emotional and social needs. According to Kevin Johnson, M.D., assistant professor of pediatr......CO, April 23 -- The number of patients with cystic fibrosis (CF) whodie waiting for lung transplants will likely increase if surgeons are requiredto follow new international wait-listing guidelines and current geographicdisparities in waiting times persist, a surgeon from the University ofPittsburgh Medical C......lthe notion that interleukin-6 (IL-6) causes liver fibrosis or cirrhosis andinstead suggest that it is important to the liver's recovery. So encouraged isthe research team by these findings, being presented at today's sessions ofExperimental Biology '99, that it plans to initiate further studies to determine...UNC-CH Studies Show Medicine Can Reverse Osteoporosis From Transplants, Cystic Fibrosis
...s transplants, including lungtransplants in cystic fibrosis patients. The studies, described at the 12...e, conducted the research with help from 35 cystic fibrosis patients. Allpatients had undergone lung transplants because of failing health. "Several cli...Controlling Collagen Levels May Be Key To Fighting Organ Failure Caused By High Blood Pressure
...rough the vessels and blood pressure increases. As fibrosis progresses, cells in the heart and vessels are encased in a"cement-like" collagen mesh. The heart and vessels become stiffer, and theircells no longer can function properly. "Picture giant mastodons, large, perfectly healthy animals. The......opkins scientists studying lung damage from cystic fibrosis (CF) have found a natural "bug spray" that lung cells "squirt" on attacking bacteria. The "spray", an antimicrobial compound researchers call hTAP(human tracheal antimicrobial peptide), appears to be disabled in CF patients, increasing their vul...