Hopkins gene therapy trial is first to activate entire human immune system against prostate cancer
...odies, antigens on the cells' surface serve as red flags to the immunesystem, causing it to seek out and destroy them. "The gene we used to turn on the immune system is so good that it activateseverything," says William G. Nelson, M.D., Ph.D. "We were not surprised to seeT-cell activation, the arm of the ...UCSD cancer researchers develop new anti-leukemia strategy
...ndritic cells. These surface antigens are like red flags to T cells, stimulating them to attack. On day 8, the researchers discontinued the GM-CSF and IL-4, and began a 10-day course of IL-2, which is the main T cell growth factor, making them actively proliferate. Following that they added anti-CD3/anti-...The neighborhood matters: Packard Center scientists show cell environment is important in ALS
...nt SOD1 gene. They tagged the cells with molecular flags to make it clear which were which. The percent of wild-type cells in the animals' spinal cords ranged from 5 to 90 percent. Having wild type cells mixed in had the effect of extending mouse survival from one to eight months, depending on the number ...