Duke Study Suggests New Class Of Drugs Could Bypass Leptin Loop
...n of the department of psychiatry, began to search for the pathwayby which leptin signals the body to burn fat. Using genetically obese micethat lacked the leptin protein, researchers administered leptin to one groupand a saline placebo to the other group. Because the genetically obese miceproduced no na...AIDS Treatments Seek To Eradicate Virus, Restore Immunity
...he four-year grant is known as a Strategic Program for Innovative Researchon AIDS Therapy (SPIRAT), and i...-positive, and whoagree to be treated and followed for more than two years. All the patientswill receive a potent mixture of anti-viral drugs that includes...Shark-Liver Substance May Slow Growth Of Brain Tumors
...ults suggest that the substance, squalamine, named for the shark genus Squalus, may find a role with chem...gators also are exploring natural shark substances for use against human diseases, but this is believed to be the first evidence that squalamine may work a...Study Says Machine Sensors Applicable To Human Ills
... to study the possibility thattechnology developed for machine maintenance could be used to maintain huma...hibits complex, variable electrical activityexcept for the period just before or during sudden cardiac death when itbecomes regular. This parallels complex...DNA Imaging to Design Better Drugs
...working underBottomley's direction, is responsible for much of the development of thenew assay. Third-yea...lliams', prepared highly purified drug-DNA samples for the project andcurrently is obtaining images of new DNA complexes. Williams and Bottomley presented...Digital Speech Analysis Tests Sobriety
...h. Four speaker samples may not sound like enough for a comprehensivestudy, but Cummings said they form ...the same trend between sober andintoxicated speech for four different speakers, that's actually a lot,"she said. Also, Cummings plans to continue her rese...Use Of Surfectant Therapy Widens Gap In Death Rate Of Black And White Newborns
...ber of black and white babies." The mortality rate for all infants is about 2.5 times higher forblacks than for whites. After the introduction of surfactant, theresearchers found that black premature infants were...Testosterone May Affect Learning Skills; May Be Put In Tablet Form
...patches also deliver the hormone at a steady level for a long period. Other authors were Kathy Lesh, R.N., Donald R. Hoover, Ph.D., and Richard P. Allen, Ph.D....New Colorectal Cancer Treatment Available
... new drug in the United States approved by the FDA for the treatment of colorectal cancer. The drug, cal...e FDA, under its accelerated approval regulations, for use as a second line treatment in patients whose disease has recurred or progressed after standard t...Emory Doctors Discuss "Killing Heat" In This Week's NEJM
...ng alone and in the inner-city are at highest risk for heat stroke, as are persons who are infirm or shut...suggestions: "Since access to air-conditioning for even a few hours each day is protective, local governments in high-risk areas of the country should...Hopkins Researchers Develop Under-The-Skin Implant For Pain Treatment
...ped the first under-the-skin narcotic drug implant for the treatment of pain in cancer patients. The res...reat serious pain and may be a potential technique for the management of drug addiction. The button-sized polymer works much like the continuous-release bi...Maternal Exposure To Crack Cocaine Produces Stressed Newborns
...r said. "For adrug-using mom, this is a real setup for failure, as problems with thebaby and mother can trigger negative parenting. The trick is to get the mothersback on track, with parenting, psychiatric and addiction counseling."...Discovery Hints At Multitude Of New Targets For Drugs
... way to a new wave of drugs withfewer side effects for contraception, hormone replacement therapy, breast...y tissue, pharmacologists have traditionallylooked for subtypes of a receptor unique to that tissue," he said. "They could then design compounds that would...Alzheimer's disease center seeks patients for new drug studies
...uthwestern Medical Center at Dallas may offer hope for the millions of Americans affected by Alzheimer's ...rth Texas -- testing propentofylline, an oral drug for Alzheimer's that also may be effective for patients who experience dementia as a result of strokes. ...What Makes Tics Tick? Clues Found In Tourette Twins' Caudates
...ime, scientists have a neurobiological explanation for the variation in severity of tics in Tourette Synd...tter receptors in the brain structure responsible for carrying out automatic behaviors. They suggest that this dysfunction may underlie the compulsion to...Tacrolimus Stops Rejection Of Kidney Transplants
...nter trial to demonstrate such encouraging results for persistent kidney rejection. The study, which invo...that tacrolimus has become our preferred treatment for patients who experience refractory rejection following a kidney transplant," said the paper's lead a...Partial Liquid Breathing Improves Lung Function, Chances of Survival in Sick Preemies
...e air sacs from collapsing. Conventional therapy for this condition -- increasing the pressure and oxygen concentration inside the lung in an effort to force more oxygen into the blood stream -- can cause permanent lung damage and result in a chronic disease called bronchopulmonary dysplasia. Partial l...Study Demonstrates Safety & Effectiveness Of Asthma Drug
...ive-year debateabout appropriate use of medication for treating mild asthma. The results show that the c...lbuterol,should be used only on an as-needed basis for patients with mild asthma.Regularly scheduled use of albuterol is not risky, but neither is it neces...Scientists Produce New Anti-Malarial Compound
... of Health . That grant was recentlyrenewed by NIH for another four years. Also involved in the workare Xueliang Tao, a postdoctoral fellow in chemistry; Jared N.Cumming, a chemistry graduate student; and Donna Klinedinst, aresearch assistant in the Johns Hopkins School of Medicine.......proach..." Researchers at Johns Hopkins have shown for the first time that spending more time and money u... The Hopkins team compared standard costs and fees for laboratory and hospital care and health care worker salaries for DOT with two other strategies, conv...