Targon And Duke Cancer Center Sign $3.75 Million Agreement To Produce Advanced Anti-Cancer Drugs
...nd the Duke University Medical Center announce the formation of a research collaboration between Targon Corporation and the Duke Comprehensive Cancer Center. The terms of the agreement call for Targon's provision of $3.75 million, over the next three years, to support research and further testing of advanced a...Chemists Closing In On Commercial Potential Of Alkanes
... barriers for each reaction step from solvation to formation of thefinal alkyl hydride product have been estimated." Says Harris, an expert in femtosecond studies, "The femtosecond techniqueused in this alkane reaction study in combination with step-scan infra-redspectroscopy should be applicable to many ..."Powerful New Tool" For AIDS Is Reported In Science
...elopment. In this manner, the daily rate of T cell formation and the life-span of T cells can be measured in each person individually. In addition, this technique allows researchers to measure the rate of change in new cell development, or the 'T cell kinetics'. "The difference between kinetic and static meas...Added Benefit Found For Aspirin Use In Patients With Vessel Disease
... the aspirin treatment. Aspirin blocks the formation of cyclooxygenase-dependentvasoconstrictors, substances released by the vessel that control itsconstriction and relaxation. The benefit of aspirin on vascular function can berelated to blocking the negative effects of these substances and restoringn...Anti-Clotting Drug May Cause Potentially Fatal Platelet Disorder
...widelyused to prevent stroke as well as blood clot formation following placement ofcardiac stents, can cause a rare but potentially deadly disease. The disorder,thrombotic thrombocytopenic purpura (TTP), generally develops within four weeksof starting ticlopidine therapy. Symptoms of TTP include mass...New Research In Battling Alzheimer's Impact On Memory
...rveUniversity may have found the first step in the formation of toxic plaquebelieved responsible for the destru...try as one ages, has now been determined to be the formation of extended chain-likestructures that fold back on themselves to form the toxic structure. Paper M...Warfarin Continues To Be Underused As Stroke Preventive
...t common risk factor for stroke. Byleading to the formation of blood clots that may travel to the brain, thecondition accounts for about 80,000 strokes annually. Achieving more widespreaduse of warfarin, the researchers estimate, could prevent at least 10,000 strokesa year. The researchers examined how fre...Fat: It's Not For Breakfast Anymore; Study Finds Fat Linked To Clotting
...eam, and elevated levels can "leadto an explosive" formation of the enzyme thrombin. Thrombin is a catalyst inthe formation of fibrin, one of the essential components of a blood clot. Toomuch clotting can lead to blockages ...Widely Used Therapy May Not Be Effective In Treatment Of Acute Stroke
...s, such as heparin or danaparoid/Org 10172,prevent formation of clots and, because they act immediately, they might behelpful in an emergency situation such as stroke. Unfortunately, heparin has potentially dangerous side effects, such as anincreased risk of bleeding. The LMW heparins and heparinoids are new...Neurotransmitter-Induced Electrical Activity Identified As Key Regulator Of Synaptogenesis
... membrane protein is essential for the formation of postsynaptic glycine receptor aggregates. It remained enigmatic, however, which signals instruct a cytoplasmic protein about the presence or absence of an apposing glycinergic nerve terminal. By paralyzing cultured spinal...Extreme Fatigue Increases Risk Of Blood Clot Formation
...ves two main components: factors that promote clot formation (coagulation) and factors that remove blood clots ...tal exhaustion may increase the risk of blood clot formation in the heart arteries through impaired fibrinolysis. Impaired fibrinolysis may provide a biological...Fast Food Can Speed Up Clogging Of The Arteries
... with reactive oxygen -- plays a major role in the formation ofartery-blocking plaque. "Dietary oxidized cholesterol may contribute to atherogenesis, anddietary modification that reduces the intake of dietary oxidized cholesterol mayhave a role in the prevention and treatment of atherosclerosis," says ......rates(lipid-lowering drugs) reduce atheroma plaque formation , through an unknownmechanism. Bart Staels and Pro... in vascularmuscle cells, which participate in the formation of atheroma plaque andrestenosis after angioplasty . These vascular PPARa receptors were found toinh......t converts testosterone into DHT, might preventthe formation of prostate cancer. The National Cancer Institute (NCI) is in the midst of a large national clinicaltrial to determine if finasteride can reduce the incidence of prostate cancer.The seven-year NCI study has enrolled more than 18,000 healthy men with ...National Science Foundation Awards Knowledge And Distributed Intelligence Grants
...lic alloys used widely in engineering, involve the formation and evolution of complex defect structures on a hi...l gaps or voids; the tangles and voids lead to the formation of microscopic cracks; and cracks grow to break the wing.The multidisciplinary research team will us...Steroids May Reverse Loss Of Substance Tied To Nervous-System Diseases
...dercontrol conditions, and the peak rate of myelin formation increased by morethan 2-fold. Their findings prov...he first live look at the signals initiatingmyelin formation in live cells, Glaser said. Before his new assay wasdeveloped, researchers were restricted to simp...Restaurant Meats Higher In Suspected Carcinogens
...tures and longer cooking times areimportant to the formation of heterocyclic amines. This is the first ...previously had only been laboratory studies of the formation of the compounds. There are no established rules or guidelines for the acceptable level ofheterocycl...Mechanism By Which Estradiol Protects Women From Heart Disease Suggested By Emory Team
...l associated with dangerous atherosclerotic plaque formation haseluded researchers. Emory University researchers offer an explanation at this week's 71st ScientificSessions of the American Heart Association, suggesting that high levels ofestradiol are associated with increased levels of the prooxidant enzyme...Substance Discovered That Induces Hair Follicle Formation In The Mature Skin Cells Of Mice
...e University of Chicago have induced hair follicle formation in the mature skin cells of mice. Follicle formation is a once-in-a-lifetime event that ordinarily happens only during early embryogenesis. Their findin......imics the actual physiologicalenvironments of bone formation and bone resorption. The Company used this humanbone model system, along with its high throughput screening and medicinal chemistry capabilities, to identify the two series of drug leads reported ontoday. Signal has expanded its SERM gene regulati...