UCSF study offers insight into human circadian rhythms
...the molecular level. As the findings hint that the genetic mutation might play a role in depression, the scie...relevant gene, based on what was known about other genetic markers related to circadian rhythms. The gene was found on chromosome 17. (The mutated form was com...Mouse model reveals potential way to reduce cardiac deaths in kidney patients
...e develop metabolic syndrome as a result of both a genetic modification and a high-fat, high-cholesterol diet. To simulate chronic kidney disease, scientists damaged or removed part of the kidney. This led to a shutdown of cells that regularly dismantle and rebuild bones, causing vascular calcification. The...Fat may promote inflammation, new study suggests
... levels of messenger RNA (mRNA), which carries the genetic code instructions for cells to create the proteins. The study included 20 post-menopausal women from 50 to 70 years old who were overweight or obese and had waists larger than 35 inches. Women in this age group are at increased risk for metabolic syn...Researchers search for first sign of congestive heart failure
... at those who might be most at risk: people with a genetic tendency to retain sodium and an elevated blood pressure following stress, such as a competitive video game. The body naturally responds to stress by increasing blood vessel constriction and fluid volume inside vessels. The kidneys help with volume b...Targeting mutant B-Raf protein reduces melanoma development
...eiving the signals, to the nucleus, which contains genetic material and controls many of the cell's activities. B-Raf is one member of the chain that relays signals playing an important role in cell signaling. The protein is usually only active when needed to relay signals. In contrast, mutant B-Raf is activ...Why asthma sufferers struggle with the common cold
... the causes the IFN-beta defect. Although several genetic mutations have been linked to asthma in the past, so far none are related to IFNs....Cavity prevention tips for pre-school age children
...ecay need to be extra careful. "We know there's a genetic predisposition to tooth decay," says Dr. Soxman. Children at high risk for cavities should be discouraged from eating starchy snacks such as crackers and chips. In fact, one good way to determine if a snack is good for a child is to check their teet...Patient with drug-resistant form of HIV identified
...Centre, New York, USA) and colleagues analysed the genetic make-up of the patient's virus and assessed its susceptibility to antiretroviral drugs. Rapid progression to AIDS after infection with HIV-1 has been previously described, as has the transmission of multidrug resistant viruses. However, the unique fe...Genes for alcohol consumption identified
...ity to addiction, may be related to differences in genetic make-up. Lead researcher Dr Marcus Munaf, at the D... Bristol, said: "Our study suggests that there's a genetic basis to certain kinds of behaviour, including alcohol consumption, which may be important in influe...Mountaineering doctors hike medicine to new heights with Xtreme Everest
...s. The genetics project will track and compare the genetic profile of high altitude natives, lowlanders and summiteers to identify genes that aid survival in extreme altitudes. A separate initiative called Project Everest will recruit over 1000 volunteers to take part in cardiovascular fitness research at U...Mechanism of RNA recoding: New twists in brain protein production
...Reenan, has uncovered new rules of RNA recoding--a genetic editing method cells use to expand the number of p...en't always followed to the letter. Sometimes, the genetic recipe gets edited after cells copy DNA to RNA--a close chemical relative--during transcription. Thi...Aspirin's potential ability to prevent colon polyps may not apply equally to all
...n polyps may be strongest in those with particular genetic variants. In the March 16 Journal of the National... provided blood samples that could be analyzed for genetic factors. The current study analyzed the blood samples from participants who reported having endosc...Compound may help prevent diabetes in fast-food fans
...udied metabolic changes in the test animals at the genetic level. They found significant differences in gene expression, as measured by messenger RNA changes, between animals that became insulin resistant and those that did not, they say. Although the exact mechanism by which HPMC works is unclear, Yokoyama ...Ethical discussion should come before research
...es such as cloning and parthenogenesis, which uses genetic material from a single parent. Some scientists arg..., the possibility of creating embryos that combine genetic material from two species could open the door to unanticipated harmful consequences as easily as ben...Researchers say breast cancer in Africa may provide clues to the disease in African-Americans
...in Africans and African-Americans, suggesting that genetic factors may play a significant role in the racial ...y scientists to speculate that there may also be a genetic component contributing to breast cancer in African Americans. Alero Fregene, M.D. and Lisa A. Newma...Genetics important in age-related macular degeneration
...ong elderly individuals, we quantified substantial genetic influences on AMD, contributed new information about the heritability of advanced AMD, and established an important environmental contribution," the authors conclude. "This twin study underscores the need for a multifactorial approach that incorporat...Newly discovered pathway might help in design of cancer drugs
...ing up with the cancer cells' DNA and sticking its genetic code together so it dies. Our discovery takes that a step further, establishing that there is a way to efficiently create this type of damage by modifying the DNA itself." In the lab, Greenberg and his team used organic chemistry to create a syntheti...Gene for age-related macular degeneration discovered by Yale researchers
...ariant in the CFH gene. Hoh and her team used new genetic analysis and microscopic imaging technologies to find the genetic variant of the AMD gene. "What sets our study apart from previous research is that we used many more...Sex selection popular among infertile women
...nited States, sperm separation and preimplantation genetic diagnosis, make sex selection possible. But the pr... usually reserved for the prevention of sex-linked genetic disorders in children and are not widely used for nonmedical purposes. "Sex selection is a topic tha......ogress in the use of various techniques--including genetic mutations, post-natal dental stem cells, and tooth tissue engineering--to facilitate replacement tooth therapy development in humans. Researchers from the Forsyth Institute (Boston, MA) and the University of Texas Health Science Center at San Antonio...