Studies of growth hormone result in new class of drugs
ATHENS, Ohio--Studies at Ohio University of growth hormone and its role in diabetes, acromegaly, canc...e third U.S. patent in a series on the technology, growth hormone antagonists, which is the basis for the development of the drug termed pegvisomant. This sum...Estrogen-driven gene activates human pituitary tumors, Cedars-Sinai Medical Center researchers find
...disorders by generating excess hormones pivotal to growth and reproduction, thyroid and adrenal function. Th... linked to its insidious trigger of malignant cell growth in those organs as well. Now researchers can begin to correlate expression of the gene with stages a...Time-released capsule delivers 'growth factor' to improve coronary bypass surgery
...e heart. Researchers wanted to learn whether the growth factor therapy, designed topromote the growth of new blood vessels to replace the blocked ones, was safefor heart patients. Researchers injected...Research challenges conventional thinking on ways to treat prostate cancer
...jority of the tumor cells to go into a dormant, or growth arrested state, but that very few cells died. "Un...rease in the activity of proteins that control the growth of tumor cells. But instead of causing all the tumor cells to die, the proteins only appeared to in......d-release capsule of a substance that promotes the growth of new blood vessels showed evidence of improved b...nserted timed-release capsules of basic fibroblast growth factor (bfGF) into the heart muscle of patients scheduled for bypass surgery. Patients received eith...UF study shows contemporary method accurately predicts cancer risk
... be closely monitored -- or even treated -- when a growth is considered abnormal but not yet cancerous. The same predictive power is available with standard excisional biopsy, but that approach involves cutting the breast and removing a much larger amount of tissue. In contrast, fine needle aspiration biops...New gene therapy shows promise in improving success rate of leg bypass surgeries
...-- which short-circuits the genes that can lead to growth of an abnormal layer in the wall of the vein, and eventually a blockage. The other 16 patients in the study had conventional bypass surgery without the gene therapy. The researchers decided to study bypass surgeries of the leg rather than those of......ates theformation of new blood capillaries and the growth of fibroblasts that replace the connective tissue ...th to the repair. Inaddition honey stimulates the growth of epithelial cells that form the new skin cover over a healedwound. Honey thus prevents scarring a....... These organizations also have been tracking the growth of club drugs throughout the United States, especially among youth and young adults. At a news conference in Washington, DC, that coincided with CADCAs annual meeting, Dr. Leshner outlined how NIDA and its partners will work together to increase t...Scientists identify gene that detects DNA damage
...fer that this network is also important for normal growth control and cancer prevention." The UW team reported last year that mutations in a different member of the Mre11 complex, a gene called Nbs1, causes the genetic disease Nijmegen Breakage Syndrome, which closely resembles A-T....Growing blood vessels around clots in leg arteries may treat painful walking
...dication." Researchers are using an "angiogenesis growth factor" to create new blood vessels around clogged...being studied, called recombinant basic fibroblast growth factor (rFGF-2), has the potential to promote the growth of blood vessels around blockages, said Duk...Protein predicts prognosis for breast cancer patients
...ancer from spreading, or low angiogenesis, minimal growth of new blood vessels to supply the budding tumor, ...ession from normal to highly malignant tissue. The growth of new blood vessels tends to occur quite early for most cancers; even small tumors found via mammog...Copper-lowering drug stabilizes advanced cancer in anti-angiogenesis trial
...niversity of Michigan report they have stopped the growth and spread of the disease in a small group of pati...t one-fifth of normal for more than 90 days had no growth of existing tumors or formation of new ones, according to a paper published in the January issue of ......res from the moment of creation through subsequent growth into cholesterol crystals, which later form gallstones. And, they were able to observe crystals forming in human bile from gallstone patients in a few hours following extraction, and after 40 hours in the synthetic model. Eighty percent of all gal...People from large families may have greater risk of Alzheimer's
... "The early-life environment and its effect on the growth and maturation of children is linked to many adult...mic levels, and therefore more likely to have poor growth rates," Moceri said. Researchers also found that children who grew up in the suburbs were less likel...Eastman gives Clemson University $38 million fiber technology
...t could inaugurate a new chapter in the industrial growth of South Carolina," said Thomas M. Keinath, dean of the College of Engineering and Science. "Universities have always generated intellectual capital, but we now know they can also generate economic capital by attracting industries to the state." Re...Missouri scientist takes 'rocky' road to NASA
...llected from air or space-borne sensors to analyze growth characteristics of areas just a few yards across. "We can fly over an area and precisely map its plant quality and soil makeup -- including mineral variation and organic carbon content -- in approximately 6-foot increments," Rickman said. Armed wi...New horizons, treatments in anticancer chemistry
...and several unique approaches to inhibiting cancer growth are underway. Many new compounds, including epothi... mechanism similar to Taxol®, which stops tumor growth by stabilizing the tiny strands (microtubules) that separate the chromosomes during cell division. T...Study links one human gene to multiple diseases of old age
... by p21, either inhibit the death or stimulate the growth of neighboring cells. According to Roninson, this paradoxical growth-stimulating activity of growth-arrested cells resembles the functions of certain cells found in human cancers, suggesting that p21 may be involved in promoting the development of tu...University of Rochester awarded patent for class of drugs known as cox-2 inhibitors
...cular messengers called inflammatory cytokines and growth factors. The team also genetically-engineered two types of cells - one that produces cox-2 but not cox-1, and vice-versa - to enable researchers to identify drugs that inhibit the production of cox-2 without inhibiting the production of cox-1. Seve...