Computational innovation predicts how patients will respond to drug treatments
...d, on average, 30 clinical trials. Now, because of heightened concern over adverse drug reactions, it is not uncommon to have about 70 trials per drug. Correlating genetic profiles with drug-interactions databases may speed that process by months. For every month we save during clinical trials, it means people...CRP levels predict risk of sudden death
...l. CRP is the only abnormality that gives rise to heightened risk of sudden death once factors such as pneumonia and other conditions that raise CRP levels are factored out. The researchers found the median CRP was 3.2 micrograms per milliliter (ug/mL) in acute plaque rupture; 2.9 ug/mL in plaque erosion; 2.5 ...Young adults dont heed warning message of heart attack or stroke in family
...mily history may not adequately acknowledge their heightened future risk of disease. Overall, Kip concludes, the results indicate that health professionals need to better communicate the well-documented association between family history of heart attack and stroke and increased personal risk when working with...Heavy drinkers bear the heavy burden of bleeding stroke
... ICH. Frequent alcohol use, but not hypertension, heightened the danger of a lobar stroke. Hypertension, but not alcohol consumption, raised the odds of suffering a nonlobar stroke. The researchers also sought to determine whether variations of genes that are involved in cholesterol metabolism, called apoE2 a...Repeat stenting not always durable
...ailure causes the re-stenting procedure to fail: a heightened immune response to the presence of the metal stent triggers the vessel to begin growing new cells, a process called neointimal hyperplasia. The problem is the bare stent, not the way the stent is placed, he says. One way to overcome this problem migh...More children at risk of heart disease
...ondon, at Charing Cross Hospital, adds: "Despite a heightened awareness of the disease over the past 10 years, this has not proven to be enough. More early diagnosis is needed, so the disease can be treated more effectively." Despite being widespread, the cause of Kawasaki disease remains uncertain, but epidemi...First longitudinal study on lesbian health
...ars. "Although it is assumed that lesbians are at heightened risk for alcohol-related problems, very few studies have addressed risk and protective factors," Hughes said. "Moreover, few studies have included comparison groups of heterosexualwomen." Her sample one of the most diverse samples ever included in ...Even moderate drinking raises blood pressure in some men
...ar span. The study included men and women, but the heightened risk of hypertension was found only in the men. Ohmori and colleagues say, "Regular drinking, including even low levels of consumption, was found to be a significant risk factor for the onset of hypertension in a general population of Japanese men." ...Early mental health intervention reduces mass violence trauma
...tly reduce risk and may even put some survivors at heightened risk for later developing mental health problems. The report is targeted to those who deliver these interventions to emotionally distressed persons following mass violence, to those who research these issues, and to employers who want to help workers...Vision loss and driving performance, stroke and physical impairment
...d Summarizes a dysphagia meeting responding to a heightened healthcare need and to determine the course of dysphagia research. Dysphagia affects a person's ability to swallow and may result in an ability to consume enough calories to nourish the body. The article identifies issues in dysphagia research, such ...Exhaustion's effect on blood increases heart attack risk
...ng, helping to explain why it is associated with a heightened heart attack risk, according to a study conducted in the Netherlands. Other studies have found the medical condition known as vital exhaustion more than doubles the risk of a first heart attack, but it is not yet fully understood how. Vital exhaustio...American Thoracic Society journal news tips for October (first issue)
...the first time that women compared with men have a heightened cough reflex sensitivity to both capsaicin and citric acid cough challenges. A similar differencebetween the sexes was also seen in the clinic for two principal diagnostic categories, asthma and gastroesophageal reflux disease. The study was publis...Young children may cope better if they remember medical procedure details
...confusions amongst various medical experiences and heightened distress during subsequent medical encounters," the researchers say. The study included 32 children between ages 2 and 7 who had undergone a voiding cystourethrogram, an X-ray of the kidneys that many children find highly distressing. The children an...UF study: Adolescent girls who set goals too high may risk anorexia
...," she said. "While there may be some occasions of heightened conflict, with adolescents driving their parents crazy, sustained periods of emotional upheaval are not necessarily normal and may be a sign something is wrong." Families can try to avoid some of these problems by emphasizing the importance of moder...July/August 2003 Annals of Family Medicine tip sheet
...ony, and emphasis on social well-being result in a heightened attention to bodily processes. This emphasis on bodily awareness among Filipino Americans offers clinicians a unique opportunity utilize this strength to enhance chronic illness management plans. Becker suggests that awareness of culture-specific ...Hostility, depression may boost heart disease protein level
...mptoms, even in the mild to moderate range, are at heightened risk for cardiac events," according to Edward C. Suarez, Ph.D., of Duke University Medical Center "Although studies have shown that hostility and depressive symptoms are associated with greater risk of heart disease, the reasons for these association...Novelty-seeking teens more receptive to tobacco advertising, new study shows
...ait at a higher risk for smoking initiation. "The heightened receptivity to tobacco advertising among youth high in novelty-seeking may be attributable to their greater need for stimulation and rewarding experiences," said Audrain. "Tobacco industry promotional campaigns, which often highlight stimulating act...Improving physical fitness, insulin sensitivity may help latino children at risk for type 2 diabetes
...sity, insulin resistance, metabolic challenges and heightened disease risk. "Obesity is now a critical, common nutritional problem in children," says Michael I. Goran, Ph.D., professor of preventive medicine and physiology and biophysics at the Keck School and study presenter. "It disproportionately affects min...Interracial interactions are cognitively demanding
... photographs of black males," says Richeson. "This heightened activity was in the right dorsolateral prefrontal cortex, an area in the front of the brain that has been linked to the control of thoughts and behaviors. Plus, these same individuals performed worse on the cognitive test after an actual interaction ...... and missed medication. "We believe that with a heightened awareness of these issues, informaticians can educate, design systems, and conduct research in such a way that we may be able to avoid the unintended consequences of these subtle silent errors," the study's authors concluded. For this article, sep...