Castagnolis discover compound in tobacco that may protect against Parkinson's disease
... but addicts who took large doses of the synthetic heroin suffered severe Parkinsonian symptoms. Neal Castagnoli, then working at the University of California at San Francisco, was one of the scientists who determined what caused the brain to turn the contaminant into a toxin that caused many of its users t...St. Paul researcher receives national award
... -- drugs derived from opium, such as morphine and heroin -- work by binding to receptors, specific protein pockets on the surfaces of cells. "As researchers gain more insight into how molecules and receptors actually recognize each other, they can tailor-make drug molecules that are more effective or more ...New study underscores effectiveness of methadone maintenance as treatment for heroin addiction
... counseling, is a far more effective treatment for heroin addiction than is simply the temporary use of meth...ethadone maintenance is an effective treatment for heroin addiction," says Dr. Alan I. Leshner, NIDA Director. "This is yet another indication that MMT should...Drug trends among American teens
...anger young people perceived to be associated with heroin use fell some in the first half of the 90s, quite ... a result of the advent of non-injectable forms of heroin use. However, since 1995 there has been some recovery in the perceived risks of heroin, which likel...UCSF Psychiatry Department receives grant to study innovative drug and substance abuse treatments
...of study will look at the effectiveness of linking heroin addicts who come into SanFrancisco General Hospital Medical Center's emergency room to methadone maintenance treatments byeither assigning them to a case manager who will move them into treatment or by giving them a vouchergood for six months at an a...Conference convenes on ibogaine, a controversial drug to treat heroin addiction
...researchersas a potentially powerful treatment for heroin addiction. The conference, to beheld on November 5 and 6, will bring together leading ibogaine experts in thefields of neuroscience, ethnography and sociology. Ibogaine is a naturally occurring psychoactive compound that is used incentral West ...Symposium on treating drug addiction -- Tip sheet
...lp cocaine addicts in the same way methadone helps heroin addicts. Currently,no medical treatment for cocaine is available. Like cocaine, the compoundaffects dopamine, a brain chemical responsible for feelings of pleasure andwell-being. Cocaine and other compounds that enter the brain rapidly tend tobe ...Pain, itself, elicits pain relief, and does so through 'reward' pathway
...n. But the phenomenon may also explain why heroin addicts, in withdrawal,can experience pain or increased sensitivity to painful stimuli. "It may be thatone of the reasons people stay addicted is to avoid going through thisunpleasant state of withdrawal," said Gear. Under other conditions, it's poss...American Association Of Pharmaceutical Scientists Announces 1998 Award Winners
...dworldwide strategy for the elimination of illicit heroin production. He is Chiefof the Laboratory of Medicinal Chemistry at the National institute of Diabetes,Digestive and Kidney Diseases at the National Institutes of Health. AAPS Research Achievement Award in Pharmacokinetics, Pharmacodynamics and DrugM...UF Psychiatrists Use Antidepressants To Treat Smoking Addiction
...f Medicine. Smoking tobacco, like smoking heroin or cocaine, is "profoundly addictive," and nicotin...cialist. "This is as hard an addiction to crack as heroin or cocaine -- right up there with the biggies." Up to now, many physicians have relied solel...Is Ritalin As Effective--And As Harmless--As It Could Be?
...Ding. Clincial studies of other drugs, such as the heroin substitutemethadone, have shown that single enantiomer forms work best. Ding and her colleagues say their results illustrate how PET can be usedto study the pharmacokinetic properties of chiral drugs. What's more, they say,because of its hig...Hopkins Researchers Develop Under-The-Skin Implant For Pain Treatment
... as an alternative to oral methadone treatment for heroin and morphine addicts in the United States. Current addiction therapy requires daily visits to a clinic for an oral dose of methadone, which occupies opiate receptors in the brain and eliminates narcotic craving and withdrawal symptoms. "In essence...