DNA Imaging to Design Better Drugs
... Lori McFail-Isom, a student ofWilliams', prepared highly purified drug-DNA samples for the project andcurrently is obtaining images of new DNA complexes. Williams and Bottomley presented this work during the 211th <AHREF="http://www.acs.org/">American Chemical Society nationalmeeting in New Orlea...Digital Speech Analysis Tests Sobriety
...yintoxicated (.05 percent blood alcohol level) and highly intoxicated(.10 percent blood alcohol level or higher, considered legally drunk in most states). Past perceptual research on this database has shown that a personlistening to the samples can reliably discriminate between sober andintoxicated speech....Hopkins Researchers Develop Under-The-Skin Implant For Pain Treatment
...er mild, local anesthetic. The polymer contains a highly concentrated powder form of the commonly used narcotic drug hydromorphone. The drug is released in a steady amount into the bloodstream over one to three months. The shape and size of the polymer, which is made at Hopkins, controls the release of pa...Johns Hopkins To Announce AIDS Capitated Care Program
...y theimpact of an integrated network of care using highly specialized services on aspecific group of patients with a medically complex disease." The goal of Moore Options is to provide care for 600 of theapproximately 3,000 Maryland AIDS patients on Medicaid, says Bartlett. Planningfor the program began ...ACTG 315 Preliminary Results: Drug Cocktail Restores Partial Immune Function
... Recent studies indicate that peoplewho respond to highly active antiretroviral therapy (HAART) --drug combi...an other patients. InACTG 315, V repertoires were highly perturbed at baseline andremained so at 12 weeks. Functional immune response, as measuredby delayed...Researchers Gain Insights Into Drugs Used For Manic-Depression
... tostop using it. At higher levels the drug can be highly toxic," said UWMedical School professor of pharmacology Lowell Hokin. "Valproate does notproduce the same toxicity." Hokin and his team have studied lithium for years in an effort tounderstand how it could control depression and mania at the...Nasal Spray Flu Vaccine By U-M Researcher Is 93% Effective
...accine is safe, immunogenic,genetically stable and highly effective. It is very gratifying to see our years... virus withthe covering from a virulent strain, is highly adaptable. "The core virus canbe stored until a flu epidemic breaks out and then 'retrofitted' with..."Super Aspirin" Holds Long-Term Benefits For Some Patients Who Undergo Balloon Angioplasty
... While pretreatment with ReoPro™ is highly effective, its average cost is estimated at $1,350 per patient dose. "The cost of this drug should bring significant attention to the question of who should receive it," said Dr. Fischman. "The issue of cost-effectiveness is vital to unde...Cancer Protection Compound Abundant In Broccoli Sprouts
Johns Hopkins scientists have found a new and highly concentrated source ofsulforaphane, a compound they identified in 1992 that helps mobilize the body'snaturalcancer-fighting resources and reduces risk of developing cancer. "Three-day-old broccoli sprouts consistently contain 20 to 50 times thea...Unique Interactive Health Kiosks Distributed In Michigan
...unded by proceeds from the state tobacco tax. The highly interactive system is the first health-related pro...ustom software, the computer kiosks will display a highly interactive program, called "Health-O-Vision," developed and updated by experts at the U-M. Current...Benefits Of Annual Mammography Outweigh Radiation Risks Of Cancer
...eening beginning at age 40 is not only safe but highly effective in reducing breast cancer deaths. Stephen A. Feig, M.D., professor of radiology at Jefferson Medical College of Thomas Jefferson University, Philadelphia, and director of the Breast Imaging Center, Thomas Jefferson University Ho...Researchers Study 'Natural' Screen For Cancer
...t provides the filtered blue light, for example. A highly sensitive camera capable of reading only the light produced by the hypericin transmits an imageback to a computer screen for closer scrutiny. "Hypericin gives us a very natural way of screening for various types ofcancer," says Rawicz, whose ...Are Deprived Areas A Greater Drain On Out Of Hours Workload?
... department in Nottingham. The authors found that highly deprived areas close to the A&E department generated high levels of work for both general practice and A&E services, with no evidence of one service substituting for the other. Carlisle et al conclude that those involved in changing out of hours ser......er forBritish Art, to develop a tutorial that used highly detailed original works ofart. Students are assigned a painting and given time to observe and study it"like a rash that has been framed." In turn, each student describes the workbased solely on what he or she sees. They learn from group discussions...Exercise, Classroom Instruction Cut Kids' Cholesterol, Study Finds
...ttitudeprogram and a physical activity program was highly effective in improving lipid(fat in the blood) profiles in this group of adolescents," Harrell said. "Ourwork is important because the few studies that have been done before on thislooked at younger children, and none has tested older children the wa...Drug Is First In Decade To Show Promise Treating Generalized Anxiety Disorder
... has shown greatpromise in treating a serious, yet highly under-recognized condition calledGeneralized Anxiety Disorder (GAD), according to new study led by Dukepsychiatrist Dr. Jonathan Davidson. Davidson said the anti-depressant drug, venlafaxine extended release(XR), is the first new therapy in...- Novel class of highly lipophilic camptothecins, known as Karenitecins,demonstrates potent oral antitumor activity, acceptable safety and appear to beinsensitive to common tumor-associated drug resistance mechanisms - BioNumerik's novel chemoprotecting agent BNP7787...Fat: It's Not For Breakfast Anymore; Study Finds Fat Linked To Clotting
...nfatty acid composition. One had palmitic acid (a highly saturated fat found inanimals); one had stearic acid (found in beef and cocoa butter) and the othertwo contained different ratios of linoleic and linolenic acid (found in corn,canola and other vegetable oils). The high-fat breakfasts consis...Most People Cant Identify Stroke Symptoms
...e Cincinnati area has been involved in a number of highly publicizedstroke studies, the local population was frequently exposed to information aboutstroke warning signs, symptoms, and emergency treatment. Therefore, a study inCincinnati may underestimate the lack of knowledge about stroke in other citieswh...Neurotransmitter-Induced Electrical Activity Identified As Key Regulator Of Synaptogenesis
...e specific receptor proteins that are highly concentrated within the membrane segment underlyin...Therefore, neuronal cultures were treated with the highly selective glycine receptor antagonist strychnine. This treatment abolished both gephyri...