Study Shows Three-Drug "Cocktail" Needed To Keep AIDS Virus Curbed
... drugs indinavir, zidovudine and lamivudine curbed human immunodeficiencyvirus (HIV) better than maintenance therapy with indinavir alone or with zidovudine andlamivudine taken simultaneously. Known as AIDS Clinical Trials Group (ACTG) 343, the study was conducted among anoriginal group of 509 patients --...Microwaves May Provide Early Detection Of Breast Cancer
... credit. Bridges knew thatmicrowaves interact with human tissues primarily according to water content.Since malignant tumors have a much higher water content than normal breasttissues, he conjectured that microwaves could provide the basis for a highlysensitive detection system, especially if an antenna co......7). CD-4 cells coordinate the overallaction of the human immune system. They are the primary target of HIV and wouldtend to decrease as HIV disease progresses. Persons who tested anonymously vs. confidentially tended to beyounger, white, slightly more educated, and more likely to be at risk for HI......n the blood of pregnant women. Oneof the proteins, human chorionic gonadotrophin (or free b hCG), is present inhigh concentrations in Down syndrome cases. The second, pregnancy-associatedplasma protein A (or PAPP-A), is present in low concentration in Down syndromecases. When combined, these two protein ma...Ovarian Hormone Could Play Key Role In Easier, Safer Childbirth
...paign documented thatrelaxin binds to cells in the human cervix.Because it binds to the same kinds of cells...ge the view that relaxinhas similar effects in the human cervix,"Sherwood said. In a separate article in the journal, relaxin was shown to promote cervicalso...World's Premier Pharmaceutical Scientists Share Latest R&D Findings
...nted an oral insulin medication that's now set for human trials with the Health Protection Branch (the Cana...e. Founded in 1986, the goal of AAPS is to improve human health through the development of better pharmaceuticals. For more information about AAPS, visit ou...Encapsulating Insulin-Producing Cells For Possible Diabetes Therapy
... is anatural component of the lubricating fluid in human joints as well as thevitreous gel that fills the e...abetics took for years until there was recombinant human insulin," she added."We know the human body can tolerate it." Grinstaff's chemistry team als...UCSF Study Finds DHEA Benefits Cardiovascular Function
...rmone is both safe and beneficial, Zellner said.No human studies examining the cardiac effects of DHEA have been completed,which is essential before any recommendations involving the drug can be made,Zellner said. The study was funded by the UCSF Foundation for Cardiac Research. Otherresearchers i......urg, was the first to induce a plant to express an human protein with enzymatic activity. That achievement ...ossibility of using plants as factories to produce human proteins that can be used in pharmaceuticals. The tobacco planted at Virginia Tech's agricultural ...Researchers Splice Severed Spinal Cords
...ural cases of paraplegia in dogs early in 1999,but human clinical trials are at least two years away. T... injuries, and some methods have moved to tests in human spinal cordinjuries. Borgens' research is supported in part by the Department of Defense and the...American Association Of Pharmaceutical Scientists Announces 1998 Award Winners
...de.Founded in 1986, the goal of AAPS is to improve human health through thedevelopment of better pharmaceuticals. For more information about AAPS, visitour web site at www.aaps.org ....Discovery: Experiments Confirm Novel Eye Pigment Controls Circadian Rhythm
..., Sancar said. Human Genome Projectstaff found the human CRY1 but not its function. He and his students discoveredthe CRY2 gene with Human Genome Sciences Inc. researchers. They have applied fora patent on the work, which was supported by NIH....WFU And IntraVec To Develop Innovative Cancer And HIV Treatments
...ividing cells, including normal cells. In human patients, the scientists hope that the altered tox...caltrials early next year at Baylor, and that once human efficacy is established,more intensive development will follow. She said that the company presents a...New Drug Boosts The Power Of Traditional Cancer Therapies, UF Animal Studies Show
... announced it has begun Phase I clinical trials in human patients with advanced cancers to test the safety and maximum tolerated doses of combretastatin. Following successful Phase I trials, further clinical testing would be required to measure the drug's effectiveness, to determine dosages and to compare ...New Vaccine Being Tested In Prostate Cancer Patients
...ey hope will thwart prostate cancer. Now in early human trials,the vaccine is the first made synthetically to target abundant, but elusive,carbohydrates on the surface of tumor cells. The development will be outlined in the November 20 Web edition of the Journalof the American Chemical Society, published ......o antiviral drugs such as AZT. Once HIV invades a human cell, reverse transcriptase (RT), one of three enzymes used by HIV, reads the retrovirus's genetic material, RNA, and synthesizes DNA, which codes for viral proteins that commandeer the infected cell's protein-making machinery. In an article publish......drugs, Signal also developed a proprietaryin vitro human bone model system that mimics the actual physiologicalenvironments of bone formation and bone resorption. The Company used this humanbone model system, along with its high throughput screening and medicinal chemistry capabilities, to identify the tw...Maternal Tissue Typing Could Improve Selection Of Kidney Transplant Donors
... (NIH) have discovered that cellular markers, or human leukocyte antigens (HLA), on maternal tissue can provide valuable information for identifying the most suitable donors for individuals in need of kidney transplants. The new finding was reported Dec. 3, 1998, in The New Engla......ell carcinoma and hepatitis. "The growing body of human data in severalcancers and viral infections is leading Maxim into a clinical developmentprogram that focuses Maxamine as an immuno-modulator that may be used broadly toimprove cytokine therapy, cancer vaccines and other stimulators of the immunesyste....... Fincham says. Tooth enamel begins to form in the human embryo when a specialized layer ofcells, called ameloblasts, in the embryonic tooth bud secretes amelogeninproteins. The amelogenins self- assemble to form the extracellular matrixwithin which the inorganic crystals of mineral start to form. "The e...