'Exercise Hypertension' occurs when cells can't 'relax,' Hopkins researchers find
So-called "exercise hypertension," an abnormally high spike in blood pressure experienced by generally healthy people during a workout, is a known risk factor for permanent and serious high blood pressure at rest. But who gets it, and why, has been largely unknown....... Now, Johns Hopkins scientists say they have reason to believe that the problem is rooted in the failure of cells that line th...Higher folate intake associated with decreased risk of hypertension in women
John P. Forman, M.D., of Brigham and Women's Hospital and Harvard Medical School, Boston and colleagues analyzed data from two studies (93,803 younger women aged 27 to 44 years in the Nurses' Health Study II [1991-1999] and 62,260 older women aged 43 to 70 years in the Nurses' Health Study I [1990-1998]). The participants did not have a history of hypertension. Baseline information on dietary fol...Hypertension: On the Pill? Tell your dentist
Hypertension, a controllable and preventable disease (and more commonly known as high blood pressure), affects 1 in 4 American adults. Causes are unknown in 90 percent of all cases. However, the most common cause of secondary hypertension in women is oral contraceptive use, according to a report in the November/December issue of General Dentistry, the Academy of General Dentistry's (AGD) clinical...Signaling pathway may be key to understanding roots of hypertension
Defeating high blood pressure may be a matter of a little molecular manipulation. ...Some drugs for hypertension, such as so-called ACE inhibitors, block specific receptor proteins on the cell. But researchers at Jefferson Medical College instead have looked to a certain molecular pathway called the Gq signaling pathway, showing that it plays an important role in developing various models of hype...Studies examine risk factors and potential consequences associated with prehypertension
CHICAGO A substantial proportion of Americans have prehypertension (blood pressure above optimal levels, but not clinical hypertension) which is associated with an increased prevalence of other risk factors for heart disease and stroke and is also associated with potential increased risk for hospitalization and death, according to two articles in the October 25 issue of , one of the JAMA/Archiv...Stanford to test effects of drug widely used for pediatric hypertension
STANFORD, Calif. - The National Institutes of Health awarded the Stanford University School of Medicine a $4.3 million contract to test whether a drug commonly used to treat hypertension in pediatric patients actually works safely and effectively in children....... ...It's the second contract under a federal program established to address the pharmaceutical industry's failure to study certain dru...Pioglitazone HCI shown to lower blood pressure in hypertensive patients with type 2 diabetes
Orlando FL, June 5, 2004 Type 2 diabetes and hypertension are commonly associated conditions, both of which carry an increased risk of cardiovascular disease. Results of a large, open-label, multi-center, observational clinical trial show that treatment with the oral anti-diabetic agent pioglitazone HCl in people with type 2 diabetes has beneficial effects in reducing hypertension. The finding...Improvements in prescribing medications for hypertension results in better outcomes and cost savings
Adherence to evidence-based prescribing guidelines for hypertension (high blood pressure) could result in substantial savings in prescription costs for elderly patients, and up to $1.2 billion nationally, according to a study in the April 21 issue of The Journal of the American Medical Association (JAMA).... ..."More than 60 percent of Americans aged 65 years and older have hypertension," the aut...Moderate amounts of alcohol may help prevent death from CVD in men with hypertension
CHICAGO Light to moderate alcohol consumption may reduce the risk of death from cardiovascular disease (CVD) in men with high blood pressure, according to an article in the March 22 issue of , one of the JAMA/Archives journals....... According to background information in the article, previous studies have shown an inverse association between moderate alcohol consumption and CVD mortality, but...'White coat hypertension' common among sleep apnea patients
(NORTHBROOK, IL, March 8, 2004) Patients with sleep apnea may be commonly misdiagnosed with hypertension, says a study published in the March issue of CHEST, the peer-reviewed journal of the American College of Chest Physicians. In the study, one third of patients with sleep apnea who were physician-diagnosed with hypertension actually had "white coat hypertension" (WCH), a condition character...Home blood pressure monitoring helps patients manage hypertensive drug treatments
Patients who monitored their blood pressure at home were able to decrease blood pressure medication and slightly lower their costs, according to a study in the February 25 issue of (JAMA). ...... Jan A. Staessen, M.D., Ph.D., from University of Leuven, Leuven, Belgium, and colleagues from the Treatment of Hypertension Based on Home or Office Blood Pressure (THOP) Trial Investigators, compared s...Trials on hormone therapy and hypertension treatment change practice, medication usage of patients
Recent results from clinical trials on hormone therapy and treating hypertension have changed the way physicians prescribe and the way patients use certain medications, according to two studies in the January 7 issue of (JAMA).... ...In the first article, Adam L. Hersh, M.D., Ph.D., of the Stanford University School of Medicine, Stanford, Calif., and colleagues examined the national trends in h...Standardized blood pressure measurement could improve hypertension prevention, care in the Americas
This release is also available in <A Href= "http://www.eurekalert.org/staticrel.php?view=pahosbp121903es..."> Spanish .... ......Hypertension (high blood pressure) affects approximately 140 million persons in the Western Hemisphere. Until now there has been no standard approach to measuring blood pressure that has been accepted for use in research studies in all the countries of the Americas.... ...Beta-blocker or calcium antagonist-based therapies equally effective in treating hypertension
Hypertensive patients with coronary artery disease had similar outcomes when they took a beta-blocker therapy or a calcium antagonist-based therapy, according to a study in the December 3 issue of The Journal of the American Medical Association (JAMA). ... ...According to background information in the article, despite conclusive evidence of the effectiveness of medications to treat high blood pr...Women treated more aggressively for hypertension, yet results similar to men
ORLANDO, FLA. -- Duke University Medical Center researchers have found an interesting paradox about gender differences in heart disease -- women have a greater burden of hypertension than their male counterparts and they receive more aggressive treatment for it, yet they obtain no better blood pressure control....... Since their study also found that the impact of hypertension on mortality or rec...NHLBI study finds hostility, impatience increase hypertension risk
Impatience and hostility--two hallmarks of the "type A" behavior pattern--increase young adults' long-term risk of developing high blood pressure, according to a study funded by the National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health. Further, the more intense the behaviors, the greater the risk. ... However, other psychological and social factors, such a...Research suggests how steroids cause diabetes and hypertension; liver plays critical role
St. Louis, July 17, 2003 -- Steroids called glucocorticoids are critical for treating diseases such as asthma, arthritis and pain syndromes, but they also can trigger diabetes and hypertension. Research at Washington University School of Medicine in St. Louis now shows why these commonly used drugs have such dangerous side effects.... ...The team found that a protein called peroxisome proliferato...Non-drug, treatment for hypertension gets further physiological backing in AHA's Hypertension Primer
Fort Lee, NJ - May 7, 2003 - A recently published third edition of the American Heart Association's textbook, Hypertension Primer, is providing further support for the new non-drug hypertension treatment device, RESPeRATE .... ......This third edition includes a new chapter which reviews the link between respiration and blood pressure and suggests a physiological basis for the therapeutic effect...Stiffness of aorta predicts stroke deaths in hypertensive patients
DALLAS, April 4 For the first time, researchers have linked the stiffness of the aorta (the major artery that carries blood from the heart to the rest of the body) to fatal stroke regardless of other stroke risk factors, according to a study in today's rapid access issue of Stroke: Journal of the American Heart Association.... ... Aging, environmental and genetic factors decrease the elasticity...Release of results of Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial
... ...The National Heart, Lung, and Blood Institute (NHLBI) will hold a press conference at 9:30 a.m. on December 17 at the National Press Club in Washington, D.C., to release the results of the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT).... ...ALLHAT is the largest high blood pressure clinical trial ever conducted. The long-term, multi-center trial com...CHICAGO, Nov. 20 Young adults who fume at the slowpoke ahead of them on the freeway may be racing toward high blood pressure, researchers reported today at the American Heart Association's Scientific Sessions 2002. ... This pioneer study examined the relationship between the feeling of being pressed for time and impatience with the development of hypertension in young urban adults. Time urgency...Inflammation may increase stroke risk in men with hypertension
DALLAS, Nov. 1 Proteins associated with inflammation may help identify different levels of stroke risk in men who have hypertension, Swedish researchers report in today's rapid access issue of Stroke: Journal of the American Heart Association. ... Although hypertension (high blood pressure) is a major risk factor for stroke, many people with the disease don't have strokes. Even among people wit...FDA approves INSPRA, an aldosterone blocker for the treatment of hypertension
PEAPACK, N.J. (September 30, 2002) -- The U.S. Food and Drug Administration (FDA) granted marketing approval for Pharmacia's INSPRA ...Approximately 50 million, or one in four, adult Americans, have high blood pressure. Of those, 73 percent are not adequately controlled, and are at increased risk of heart attack, stroke, kidney failure, damage to the eyes, heart failure an...Blood pressure drug shown to cut stroke, death risks in common form of hypertension
ANN ARBOR, MI A drug that reduces high blood pressure in people with a form of the disease that's common later in life also cuts their risk of stroke and death, and does it better than another hypertension drug, a new study finds....... In the Sept. 25 issue of the Journal of the American Medical Association, an international team of researchers report that patients over age 55 who took a drug c...Psychological distress may predict hypertension
Researchers at the University of Pittsburgh and the University of British Columbia reviewed the results of 15 studies published between 1972 and 2000 that assessed the link between psychological distress and hypertension development. The studies measured subjects' levels of anger, anxiety, depression, defensiveness, social support, hopelessness and other psychological factors, and then looked at...Viagra for alleviation of pulmonary hypertension?
Results of a preliminary study in this week's issue of THE LANCET suggest that Viagra may have a future role in the treatment of pulmonary hypertension (increased blood pressure in the pulmonary artery), a severe and potentially fatal condition causing respiratory impairment. ...... Lung fibrosis (scarring of the lungs due to inflammation of the alveoli) can be complicated by pulmonary hypertensi...Fitness level may predict womens hypertension risk
A woman's physical fitness level may mitigate the effect of stress on her risk of developing high blood pressure, according to a new study.... ..."We think these initial findings are sufficiently positive to encourage a randomized controlled trial that will provide a better test of the independent effects of cardiorespiratory fitness on responses during stress," says author Rod K. Dishman, Ph.D....Drug improves survival in primary pulmonary hypertension patients
DALLAS, Aug. 27 Long-term use of a vasodilator drug can significantly increase survival and improve quality of life in patients with primary pulmonary hypertension (PPH), according to the first multi-year study of the agent. The research is published in today's rapid access publication of Circulation: Journal of the American Heart Association.... ... The intravenous use of epoprostenol increase...Babies fond of salt have higher blood pressure, a granny with hypertension
DALLAS, Aug. 9 Within three days of birth some babies exhibit a unique response to salty taste and the response is strongest in babies who have at least one grandparent with a history of hypertension, according to new research reported in today's rapid access issue of Hypertension: Journal of the American Heart Association....... Healthy babies who had a "preferential response" to salt taste...Hypertension is study focus of $10 million NIH grant to MCG
A team of researchers is putting together key pieces of the puzzle of hypertension - stress, genetics, sodium retention and fitness - to define the role of each in a condition that impacts 20 percent of all adults and an even higher percentage of black adults....... The Medical College of Georgia researchers have received a $10 million Program Project grant from the National Institutes of Healt...Reducing hypertension in the elderly leads to a significant reduction in the incidence of stroke
(Prague, 27 June 2002) Results from the SCOPE* study, examining the effect of antihypertensive treatment in elderly patients with mild hypertension, are presented for the first time today at the joint meeting of the International Society of Hypertension and the European Society of Hypertension, Prague. ...... These results show a significant 28% risk reduction (p=0.041) in non-fatal strokes in...New pathway for treating hypertension-related kidney failure studied
A Medical College of Georgia researcher is tracing the pathway that leads people with hypertension to kidney damage and possible kidney destruction....... He's found a key vasodilator that is degraded in hypertension and the potential for developing drugs that prevent organ damage in these patients....... "In every form of hypertension, except pulmonary hypertension, which is limited to the lungs...CONVINCE trial results unveiled at annual hypertension meeting
An international hypertension study of more than 16,000 patients found that patients treated with three-year sustained blood pressure control with extended-release verapamil (COVERA-HS) or standard of care therapy (atenolol or hydrochlorothiazide) had similar incidences of heart attack, stroke and cardiovascular death. ... ...Data from the CONVINCE (Controlled ONset Verapamil INvestigation of Car...Impaired sodium excretion after stress contributes to hypertension in blacks
Some young, healthy blacks continue to retain sodium even after the stress that drove their blood pressure up is gone, a situation that keeps blood pressure and volume elevated for prolonged periods and puts them at risk for hypertension, researchers said....... One third of the 118 black males and females age 15 to 18 in the Medical College of Georgia study had an impaired ability to eliminate s...Family history of hypertension is related to maladaptive behavioral responses
WASHINGTON Peoples risk for hypertension associated with having a parental history of hypertension may be influenced by observing how their parents handled stress, says researchers who examined relations among numerous behavioral responses and family history of hypertension. This study, reported on in the May issue of Health Psychology, finds that offspring of hypertensive parents react more neg...XALACOM more effective than Cosopt for IOP reduction in patients with glaucoma or ocular hypertens
Fort Lauderdale, Florida, USA (May 8, 2002) XALACOM (fixed combination latanoprost 0.005% and timolol 0.5%) once-daily is more effective for the reduction of intraocular pressure (IOP) than Cosopt (fixed combination dorzolamide 2% and timolol 0.5%) twice-daily in patients with open-angle glaucoma or ocular hypertension, according to a study presented at the annual conference of the Association f...Mayo Clinic researchers find significant renal artery stenosis among hypertensive patients
ROCHESTER, MINN. -- Mayo Clinic researchers have found that a screening X-ray of the aorta among patients with hypertension undergoing coronary angiography is safe and identifies a significant prevalence of incidental renal artery disease.... ...In their study published in the April issue of Mayo Clinic Proceedings, researchers found a significant prevalence (19 percent) of renal artery narrowing...Myocarditis plus pulmonary hypertension means transplant sooner
DALLAS, March 19 Pulmonary hypertension can predict death for people with myocarditis and suggests the need for a heart transplant or other aggressive therapy sooner, according to a report in todays rapid access Circulation: Journal of the American Heart Association. ...Pulmonary hypertension is a lung disorder in which the blood pressure rises in the pulmonary artery, the blood vessel that car...Alcohol linked to decreased hypertension risk in young women
Moderate alcohol consumption can lead to a reduced risk of developing hypertension in young women, according to researchers from the Massachusetts General Hospital (MGH) and Brigham and Women's Hospital (BWH). The study results, published in the March 11 Archives of Internal Medicine, use data from the Nurses' Health Study II, which is based at BWH.... ... "For women in their 20s to 40s, we fou...NHLBI study shows vast majority of middle-aged Americans at risk of developing hypertension
Middle-aged Americans face a 90 percent chance of developing high blood pressure at some time during the rest of their lives, according to a new study supported by the National Heart, Lung, and Blood Institute (NHLBI). ... However, the study also had some good news for Americans: The risk of developing severe degrees of high blood pressure has decreased in the past 25 years, due partly to impro...