MMP enzymes play key role in stability and breakdown of atherosclerotic plaques
An Emory University scientist who pioneered the hypothesis that enzymes called matrix metalloproteinases (MMP...ge of the blood flow. Dr. Galis has pioneered the hypothesis that MMPs enable this step-wise process by breaking down the scaffolding, called the extracellular m...Cancer patients' loss of taste, smell compromises treatment
...r side effects of treatments. Zervakis said their hypothesis is that patients who receive the flavor enhancers will lose less weight and will show higher immune status at their eight-month checkup than patients who do not receive the flavor enhancers. In previous studies conducted by Schiffman, elderly patie...Impaired sodium excretion after stress contributes to hypertension in blacks
...increased risk for hypertension have supported the hypothesis that they have an exaggerated response to stress, ...T)he results of this study provide support for our hypothesis that stress-induced impaired pressure natriuresis leads to an extended period of elevated blood pres...American Thoracic Society Journal news tips for May (second issue)
...edthat the groups findings confirmed their initial hypothesis that airway acidification from withinthe body is strongly related to the inflammatory process in the three diseases studied. However,the mechanism seems to differ between asthma, which is predominately characterized byinflammation associated with eo...CONVINCE trial results unveiled at annual hypertension meeting
... of this study would result in confirmation of the hypothesis that all treatment regimens would provide a similar positive impact in preventing cardiovascular events. The standard of care arm has been shown in previous trials to provide benefit in reduction of cardiovascular events. CONVINCE confirmed that ex...RSV prevention protects preemies' lungs for many years
...American Journal of Medicine , lend support to the hypothesis that respiratory syncytial virus (RSV) can contribute to the development of asthma. "Preventing these premature infants from contracting an RSV infection during their first winter had long-term benefits for their health," said Sally Wenzel, M.D., co-...News tips from the June issue of Stroke: Journal of the American Heart Association
...nal vessels, called arterioles. "There has been a hypothesis for some time that some vascular cause other than the aging process itself was associated with Alzheimer's and stroke," says Tien Yin Wong, M.D., M.P.H. "This study shows that people with cognitive dementia are more likely to have pathological chang...Breastfeeding associated with lower risk of childhood obesity
...Health Information Team, Edinburgh, UK, tested the hypothesis that breastfeeding is associated with a reduced risk of obesity in around 32,000 Scottish children. The BMI (body-mass index) of the children was assessed between the ages of 39 and 42 months, at which time breastfeeding status during early infancy (...How does serotonin effect depression
...hereby reducing their serotonin levels. "It is our hypothesis that reducing serotonin in a person who is vulnerable to depression will cause depressive feeling while the same procedure in someone who is not vulnerable will have no effect," Dr. Delgado says. "We believe that the serotonin depletion procedure mig...No evidence that MMR vaccine is associated with autism or bowel disease
... autism, or developmental regression, and that its hypothesis has been satisfactorily tested by scientifically reliable studies."...Urine test predicts Alzheimer's disease
...n to be smaller as measured in an MRI scan. "One hypothesis is that, in AD, healthy brain tissue is damaged by the local formation of large amounts of free radicals," said Pratic. "Isoprostanes are the byproducts of fats in the human body that were warped by free radical attack. They then accumulate in CSF, b...Angiogenesis reduces leg pain from clogged arteries
...in both peak walking times and the ABI support the hypothesis that perfusion, or blood flow, was improved in these patients,"Annex said. While the mechanism of the beneficial effect is not clear, Annex speculates that the rFGF-2 might have caused new vessels to grow around blocked arteries, or may have so...Hypertension is study focus of $10 million NIH grant to MCG
...he children also will get genotyping to pursue the hypothesis that although all the children may increase their nitric oxide levels with exercise, some have a genetic predisposition to a better response, Dr. Barbeau said. "I think this is one of the reasons that, if you take two people who are similar and put t...Physical activity may improve survival and quality of life
...rapolations of data from other studies support the hypothesis that breast cancer patients may survive longer if they are physically active. "At least weight gain and obesity are linked to relapse. Obesity seems to be a problem for everything. As for hormones, obesity is linked to levels of oestrogen, insulin a...Schizophrenia may be caused by an interaction of genes and viruses in glia cells
... open access journal BMC Psychiatry presents a new hypothesis that may explain the causes of the psychiatric disease, schizophrenia. The hypothesis hinges on glia, a special type of cell, which is important for the maintenance of the connections be...Researchers identify pathway that helps keep weight in check
...uthor Eric Bachman, M.D., Ph.D., Lowell tested the hypothesis that betaARs were behind the process of diet-induced thermogenesis by creating a group of knockout mice lacking all three of the known beta adrenergic receptors (beta-less mice). Over an eight-week period, the researchers then compared the beta-less ...Cardiac disease significantly more debilitating for women than for men, new study finds
...t. The authors believe their findings support the hypothesis that social support is an important factor associated with impaired quality of life among women. Presentation: "Gender Differences in Quality of Life Among Cardiac Patients," Charles F. Emery, Ph.D., David J. Frid, M.D., Tilmer O. Engebretson, Ph...Blocking pathway overcomes tumor vessel resistance to radiation
...ls are often resistant to the therapy. Our initial hypothesis was that the cell survival pathways that allowed the blood vessels to survive were activated by growth factors from the tumor cells. We were surprised to find that cell survival pathways were activated not only by these growth factors but by the ther...Study disputes link between increased birthweight and reduced blood pressure later in life (p 659)
... blood pressure in adult life. The 'fetal origins' hypothesis proposes that impaired fetal development leading t...e; specifically, previous research supporting this hypothesis has suggested that a 1 kg increase in birthweight is associated with a 2-4 mmHg reduction in systoli......leads to restenosis. In the study they tested this hypothesis by using a deactivated virus to deliver EC-SOD to cells in the arterial walls of animals. Researchers treated 18 New Zealand white rabbits with the gene and 18 with placebo. The animals were analyzed two and four weeks later to determine if the gen...