Stat5 protein inhibits spread of breast cancer cells
...ssue of the Journal of Clinical Oncology, the team identified Stat5 as a biomarker of a type of breast cancer that is associated with a favorable prognosis in patients. In fact, in breast cancer patients whose tumors had not yet spread to the nearby lymph nodes, loss of Stat5 was associated with a nearly 7.5-f...Substance protects resilient staph bacteria
Researchers have identified a promising new target in their fight against a dangerous bacterium that sickens people in hospitals, especially people who receive medical implants such as catheters, artificial joints and heart valves. A substance found on the surface of Staphyloco...Association publishes blueprint to strengthen stroke care from prevention through recovery
...d judge the success of interventions for each area identified in this blueprint." Creating stroke systems of care will be easier if U.S. Congress passes the Stroke Treatment and Ongoing Prevention Act, known as the STOP Stroke Act, Schwamm said. The House version passed by unanimous consent last June, but Co...Rat whisking may provide insight into debilitating eye disorder
...neural circuits controlling reflexes that had been identified prior to the UCSD physicists' discovery were negative feedback loops, in which sensory input leads to motor output that withdraws sensors from the source of a stimulus. For example, such a reflex occurs if you accidentally touch a hot stove. On the ...NHS Trusts meeting government target on stroke units 'in name only'
...f a stroke unit, say the authors, but research has identified some key organisational features that reduce death and disability among stroke patients. These include coordinated multidisciplinary rehabilitation; staff with a specialist interest in stroke or rehabilitation; routine involvement of carers in the r...Inflammatory cells highly promising target in NF 1
...ive treatment even though the responsible gene was identified more than a decade ago. Currently little can be do...m, Jr., M.D. and Feng-Chun Yang, M.D., Ph.D., have identified a promising target to treat the symptoms of neurofibromatosis. They hope to begin preliminary testin...AHA urges earlier diagnoses, referrals for PCI in women
...bout the effectiveness of PCI in women. The panel identified three important areas for improving women's treatment: Diagnosis and early referral for treatment. Women face great delays for stenting or angioplasty. By contrast, men are usually promptly referred for these procedures for suspected cardiovascul...Cholesterol under-treated in high-risk women in managed care study
...ied a 1.1 million-member managed care database and identified 8,353 women who had established cardiovascular disease at the start of the study or were otherwise at high risk because of diabetes or multiple cardiac risk factors and had not recently been on cholesterol-lowering therapy. Laboratory and pharmacy ...Women's heart risk underestimated by doctors, resulting in less preventive care than in men
...g female consumers. Fifty-seven percent correctly identified heart disease or a heart attack as the leading cause of death in women overall. Caucasian women (62 percent), more so than African-American (38 percent) and Hispanic women (42 percent), made this link. "This is a significant finding because racial ...New research could help physicians tailor asthma therapy in children
Researchers have identified specific asthma characteristics in children that could help determine the type of asthma treatment they will best respond to. These findings were published in the February 2005 Journal of Allergy & Clinical Immunology (JACI). The JACI is the peer-re...Feb. 1, 2005, Annals of Internal Medicine tip sheet
...e. The patients at low risk for complications were identified using a commonly used scoring system, the Pneumonia Severity Index. An editorial writer says that the decision to treat a patient with community-acquired pneumonia at home or in the hospital is very important (Editorial, p. 215). Inpatient care is ex...Association of herpesvirus with lung disorder questioned
...vestigators concluded. In contrast, the 2003 study identified evidence of HHV-8 in ten of 16 samples from U.S. patients with primary pulmonary hypertension. The researchers noted that while their results call the earlier study results into question, there are other possible explanations for the divergent data. ...UCSD-Salk team show protein's gene-silencing role in development of nervous system
...termined that SCPs are a component of a previously identified master gene complex called REST/NRSF, which is known to control neuronal genes. In their investigations with mice and fruit flies, the scientists found that REST/NRSF recruits SCPs only to neuronal genes. "These findings suggest a way to expand th...Researchers discover genetic variant that may explain why women develop M.S. more than men
... a Mayo Clinic-led international research team has identified a genetic variation that may explain it. The report from collaborators in Minnesota, Northern Ireland, Belgium and Italy appears in the Jan. 27 online publication of the journal Genes & Immunity ( http://www.nature.com/gene/ ). Significance of the...Mayo Clinic researchers identify new form of muscular dystrophy in adults
ROCHESTER, Minn. -- Mayo Clinic researchers have identified a previously unknown form of muscular dystrophy, a...ssive weakness and muscle degeneration. This newly identified form develops after age 40 and causes heart muscle damage, limb muscle weakness and nerve damage. Th...People wounded in tsunami at risk of undetected fungal infections
...t case of a fungal infection, called mucormycosis, identified in a 56-year-old man who was transferred from Sri Lanka to a Sydney hospital for treatment after being injured when the tsunami hit on December 26, 2004. The mainstay treatment for mucormycosis is early surgical intervention to remove all dead an inf...Health initiatives can help peace building in the Middle East
...ionals since 1995. In its first initiative CISEPO identified hearing loss as an important health issue for the region and helped broker the creation of the Middle East Association for Managing Hearing Loss (MEHA) the first joint Arab and Israeli professional association. The cross-border project led to Pales...Thinking of prepositions turns brain 'on' in different ways
...University of Iowa. "For example, we have identified the anterior left temporal lobe as being critical for proper nouns, whereas the left inferior prefrontal/premotor region is important for verbs," Tranel said. "The collaboration between myself, a neuropsychologist, and professor Kemmerer, a neuroling...Cardiovascular risk factors in midlife strongly linked to risk of dementia
...etes, hypertension, high cholesterol, and smoking) identified at midlife (age 40 to 44) was associated with a 20 to 40 percent increased risk of dementia in later life. Compared to those with no risk factors, those with two of the risk factors were 70 percent (or .7 times) more likely to be diagnosed with demen...More studies on risks and benefits of COX-2 inhibitors published in Archives of Internal Medicine
... prescribed warfarin. "During the study period, we identified 98,821 elderly patients continuously receiving warfarin," the researchers report. "Of those 361 (0.3 percent) were admitted to the hospital with upper GI hemorrhage. After adjusting for other potential confounders, case patients were significantly ...