New insight into heart failure suggests novel drug target
...ellular mechanism that underlies heart failure and identifies a promising new method for stalling the progression of the disease." The team reports its findings in the October 2003 issue of The Journal of Clinical Investigation. The research was funded by the National Institutes of Health, the Burroughs Wellcom...HFES Annual Meeting papers feature work on critical health and safety issues
...uilds on previous research with drowsy drivers and identifies an appropriate design for a drowsy driver detection interface with user-centered design principles central to the development. The researchers consulted design and usability experts and a representative group of drivers about their perceptions, pref...Whole-breast irradiation after lumpectomy may protect women from recurrence long term
...ived whole-breast irradiation following lumpectomy identifies a clear benefit that may not be gained with partial breast irradiation. Gary Freedman, M.D., a radiation oncologist at Fox Chase Cancer Center in Philadelphia, Pa., presented the study today at the 45th annual scientific meeting of the American Soci...Study finds way to dramatically increase hematopoietic stem cells
...dy, published in the Oct. 23 issue of Nature, also identifies a potential treatment strategy that could duplicate this effect in patients, and the researchers are preparing clinical trials of that approach. "There are many clinical challenges facing our patients that could be met if we could expand stem cell p...Study identifies risk factors for refractive surgery malpractice lawsuits and claims
... MD, said, "This is the first published study that identifies and correlates statistically significant predictor... first time, a methodology has been developed that identifies the risk factors," said Dr. Abbott, a professor of ophthalmology and co-director of corneal and refr...Brain signals from the paralyzed or injured captured by computer
...BCI depends on an adaptive training algorithm that identifies and focuses on the particular EEG features that the person is best able to control, and encourages the person to improve that control further. These initial results suggest that people with severe motor disabilities might use brain signals to operate...Multi-hospital angioplasty improvement effort reduces deaths and complications
...quiring surgery, or if the cardiac catheterization identifies problems that warrant urgent or emergency surgery," says Moscucci. Impact of other vascular disease on angioplasty outcomes : Angioplasty opens up the arteries nearest the heart, but BCBSM-CC data show that the condition of other blood vessels in pa...Salk news: Diabetes first steps
...in the Nov. 13 issue of Nature, for the first time identifies the molecular switches that decide whether the liv...e cells' energy needs," Montminy said. "This study identifies the chemical relays that lead to this state of insulin resistance, which may help us design better t...Understanding how lymph nodes respond to infection may redefine how immune system functions
...e pathogen it is attacking. Once the immune system identifies an invader, draining lymph nodes recruit infection-fighting T-cells within 24 hours. During the next week or so, the T-cells proliferate and induce B-cells to produce antibodies specific to the invader. The result is swollen lymph nodes, which are th...Long-term follow-up of mortality in patients with community-acquired pneumonia
...December 15 issue of Clinical Infectious Diseases, identifies factors that appear to play a significant role in long-term mortality following an episode of acute pneumonia. Patients who survived the initial episode of pneumonia for at least 90 days, and who did not have HIV infection, were enrolled and followe...Study finds factors impeding bystander CPR
...ecember 2003 issue of Annals of Emergency Medicine identifies specific factors that may impede dispatcher-assisted bystander cardiopulmonary resuscitation (CPR) and could potentially be corrected through dispatcher training, variation in CPR technique, or community education. (Factors Impeding Dispatcher-Assis......herapeutic targets. TITLE: Intravital microscopy identifies selectins that regulate T cell traffic into allografts AUTHOR CONTACT: Christian P. Larsen Emory University School of Medicine, Atlanta, Georgia, USA Phone: 404-727-8465 Fax: 404-727-3660 E-mail: clarsen@emory.org View the PDF of this article at:...Race affects older Americans' likelihood of getting flu shot
...ntral Public Health. "Healthy People 2010 -- which identifies our nation's most significant health concerns and designs action plans to address these concerns -- has set the goal that 90 percent of our elderly be vaccinated against influenza annually. Our data show that we have significant work to do to reach t...Midlife brain crisis spawns late-life Alzheimer's
...man brain aging developed by a UCLA neuroscientist identifies midlife breakdown of myelin, a fatty insulation coating the brain's internal wiring, as a possible key to the onset of Alzheimer's disease later in life. Detailed in the January edition of the peer-reviewed journal Neurobiology of Aging, the model pr...Cancer markers news backgrounder: Future of cancer diagnosis, treatment lies in tumor 'barcode'
...rs" of cancer a barcode of proteins or genes that identifies cells that have turned cancerous and gives hints as to how a patient's unique tumor can be treated. These barcodes are expected to revolutionize cancer care, changing it from treatment based on a tumor's location in the body, to one that centers on a...Successful, rapid protein crystallization possible with technique developed by UCSD researcher
...erium-exchange mass spectrometry, or DXMS, rapidly identifies small regions within proteins that interfere with their ability to crystallize, or form a compact, folded state. The investigators demonstrate that once these regions are removed by what amounts to "molecular surgery", the proteins then crystallize ...C-reactive protein more than a heart disease marker
... heart disease," said Chan. "Not only that, but it identifies at least one mechanism by which the protein contributes to the development of atherosclerosis." He said this is the first time these facts have been demonstrated in living animals. Atherosclerosis is associated with deposits of fatty plaque in the w...Jan/Feb 2004 Annals of Family Medicine tip sheet
...us by Tammy A. Santibanez, Ph.D., et al Study identifies a number of barriers to vaccination for pneumococcal disease, one of the leading causes of death in the elderly. A Cost-Benefit Analysis of Testing for Influenza A in High-Risk Adults by William J. Hueston, M.D., et al There is a need for ...Incidental PET findings may reveal undetected cancer
...y requiring surgery or medical therapy. PET, which identifies areas of abnormal chemical and metabolic action, i...r, inflammation or infection. He cautions that PET identifies certain cancers but does not detect all tumors....Large-scale analysis of women with androgen excess: thorough treatment can reduce symptoms
...rm study perhaps the largest of its kind to date identifies the most common causes of androgen excess in women and compares therapeutic approaches, showing that combination hormonal therapy can improve most symptoms. Researchers at Cedars-Sinai Medical Center and the University of Alabama at Birmingham report...