Tag: "immune" at medical news
New technology blocks gene to increase immune response against deadly brain tumor cells
...t down a specific gene, researchers have regulated immune
system proteins to boost production of cells that ...derway for several years. Dendritic cells are the immune
system's most potent antigen-presenting cells those that identify "foreign" substances for destruct...
Cells of larynx may have significant immune functions
...s that line the larynx or voice box have strategic immune
functions that could have a major impact on diseas...ave a role in stopping cancer. And, we think these immune
cells are crucial in the development of asthma. We are designing experiments to test these hypothese...
Key immune system protein reduced in HIV-associated dementia patients
...ecreted by macrophages, the scavenger cells of the immune
system, is secreted at significantly reduced level...infected by HIV in the bloodstream, but unlike the immune
system's T-cells, they are not killed when infected. (The virus continues to infect the macrophages ...
NIAID forms network to tackle potentially fatal reaction to smallpox vaccine
...this network will improve our understanding of the immune
responses of these patients and should greatly inf... reactions to smallpox vaccine by evaluating their immune
responses after natural exposure to less harmful skin viruses such as herpes simplex. The ADVN Anima...
Breakthrough therapies treat Crohn's disease
...sease (CD) appears to result from an inappropriate immune
response to normal gut flora. Research has shown ..., or helminths, are rare. Helminths down-regulate immune
responses, a property that could benefit CD. Researchers from the University of Iowa confirmed the ...
Study finds once-daily Valcyte prevents serious viral infection after kidney transplant
... hepatitis, in transplant patients with suppressed immune
systems. Valcyte is an oral prodrug, or improved formulation, of Cytovene (ganciclovir), which has been widely used to prevent CMV for the past 15 years. This study compared treatment with the two medications and found that both are equally effectiv...
National Academies news: vaccines and autism
...hat the MMR vaccine might stimulate the release of immune
factors that damage the central nervous system, re.... However, no evidence has yet been found that the immune
system or its activation play a direct role in causing autism, the report notes. Autism also has ne...
Investigational drug may provide new option for preventing transplant organ rejection
...earson, MD, DPhil, have been studying a particular immune
pathway for more than ten years in collaboration w...nted from one person into another, the recipient's immune
system triggers a hostile response against the new organ, setting off a chain of events that can dam...
Clinical trial shows drug may offer a new option to prevent rejection of transplanted kidneys
...alled a co-stimulatory blocker, which prevents the immune
system from attacking the transplanted kidney in a...not as selective as this new agent in blocking the immune
system," Vincenti said. "These older drugs prevent rejection very well, but they are associated with...
University of Pittsburgh approach has lung recipients taking far fewer drugs
...that is intended to safeguard the donor organ from immune
system attack. But rejection plagues these patient...le-drug therapy, said Dr. McCurry. "Bombarding the immune
system with several very potent drugs has done little to improve the outcomes for lung transplant re...
NIH launches study of hematopoietic stem cell transplantation for severe, treatment-resistant lupus
...e roles of B and T cells, white blood cells in the immune
system, in triggering lupus symptoms. In this pilo...ls, which will become different kinds of blood and immune
system cells in the body, will then be harvested and cleaned. After the patient's bone marrow is tre...
Statins show early promise for treating multiple sclerosis
...ins promote an anti-inflammatory response from the immune
system suggest a potential in the treatment of MS. Inderjit Singh from the Medical University of South Carolina, USA, and colleagues report how 30 people with MS given 80 mg simvastatin daily for 6 months had a 44% reduction in the proportion of brai...
Can gene therapy beat HIV?
... form of HIV to deliver an "antisense" gene to the immune
cells that HIV infects. This is integrated into th...the company started treating patients by filtering immune
cells from their blood, exposing the cells to very low doses of the modified virus, and then putting...
Disruption of a gene may prevent type 1 diabetes, UVa researchers find
...e diabetes. Type 1 diabetes occurs when the body's immune
system goes haywire and attacks the insulin-making...in humans, because it is important to the body's immune
response to infections," said Dr. Zandong Yang, assistant professor of research at the Health Syste...
Tissue involved in brain development may offer new approach to stroke treatment
...eep out inflammatory factors that could trigger an immune
response and rejection. "The next step is to do the same thing in a nonhuman primate model," says Dr. Borlongan, who will continue to document exactly how the choroid plexus reduces stroke size and resulting neurological and motor function damage, at...
Cancer gene therapy news backgrounder: New ideas fuel next generation gene therapy research
...cancer that has spread. That's because a patient's immune
system reacts against the therapy, or the genes ca...fectious agent, these vectors can produce systemic immune
reactions in patients when delivered throughout the body by intravenous injection. It was a fatal im...
Preimplant test offers option of having child to serve as stem cell donor to sibling in need
...one marrow. Compatibility within the HLA minimizes immune
rejection. Yury Verlinsky, Ph.D., of the Reproductive Genetics Institute, Chicago, and colleagues report the first clinical experience of preimplantation HLA matching not involving identification of a causative gene to demonstrate the feasibility of...
New hope for HIV sufferers
A drug that suppresses the immune
system delays the onset of AIDS in patients with H...that combines an initial chronic activation of the immune
system with a progressive decrease in the number of CD4+ T cells, which are involved in the immune
Researchers define mechanism that enables stem cells to track migrating brain tumor cells
...very systems" to transport cancer-killing gene and immune
products. But not all neural stem cells take on th... to secrete interleukin 12, which elicited a local immune
response that attacked cancer cells at the tumor site and in the satellites. They also engineered ne...
Attracting an immune response to cancer
cells known as natural killer (NKT) cells are recr... tumors. NKT cells are important in the protective immune
response to cancer in mice and can kill tumor cells directly or by activating other cell types, but ...
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