New network of gastrointestinal immune cells discovered
A previously unknown network of immune cells has been discovered in the mammalian gastroi...nce, could lead to better understanding of how the immune system recognizes and responds to dangerous bacteria and viruses and to new approaches to immunizati...Study identifies predictors of HIV drug resistance in patients beginning triple therapy
...dstream at the start of therapy and how much their immune status was compromised. "We have a lot of studies showing that triple therapy works, as well as a lot of good information on the problem of resistance developing in triple antiretroviral therapy," said Richard Harrigan, Ph.D., director of the Britis...Jefferson scientists help explain statins' effects in Alzheimer's disease
...eaks up amyloid aggregates. Vaccines stimulate the immune system to break down amyloid. Statins are yet another strategy....Gene vaccine protects mice against development of Her2/neu breast cancer
...ccessful animal studies, a novel vaccine that uses immune cells as factories to produce Her2/neu protein may... treatment "produces only a passive and transitory immune reaction," Lachman said. "This vaccine, however, like many that treat microbial infections, appears ...Mayo Clinic discovery on nature of rheumatoid arthritis lung disease may offer patients therapy
...the laboratory: Certain specific T cells of the immune system, whose normal job in healthy people is to a...early and treated aggressively as a disease of the immune system. "Many doctors who have seen our results say, 'This is what I've always believed.' But no o...New therapeutic vaccine for HIV/AIDS eliminates needles and excessive toxicity
...to the skin, has demonstrated efficacy in boosting immune responses and controlling virus replication in chr...on-invasive option for HIV-infected patients. "The immune system demonstrated an unexpected capacity for recovery after DermaVir vaccinations in these monkeys...Research offers hope of new treatments for liver damage 'plague'
...first time, identified two separate populations of immune cells --macrophages--in the liver. One group of ma...causes scarring to the liver, but the next wave of immune cells, produced only a few days later, change function to break down and reabsorb the scarring. The...New 'ITN Scholars Program' provides junior faculty opportunity to develop clinical trials expertise
...ned clinical research professionals in the area of immune tolerance. The one-year fellowships will provide s...linical trials experience in the emerging field of immune tolerance therapies. Mohamed H. Sayegh, M.D., Professor of Medicine at Harvard Medical School an...Chamomile tea: New evidence supports health benefits
...ould help explain why the tea appears to boost the immune system and fight infections associated with colds, according to the researchers. Drinking the tea also was associated with an increase in urinary levels of glycine, an amino acid that has been shown to relieve muscle spasms. This may explain why the ...American Thoracic Society journal news tips for January 2005 (first issue)
...um sensitization was defined as beryllium-specific immune response demonstrated by two or more abnormal beryllium lymphocyte proliferation test results, with no evidence of nodular granulated tissue from a lung biopsy. Chronic beryllium disease was defined as abnormal blood test results plus cell infiltrat...Jefferson virologists coax HIV out of hiding
...y of replicating and wreaking havoc on the body's immune system. Now, virologists at Jefferson Medical Coll...o bring HIV out of hiding. They have shown that an immune cell protein called interleukin-7 (IL-7) can rouse the virus better than previously tried agents, ma...Pfizer's antifungal medicine VFEND receives FDA approval
...ndida infections include patients with compromised immune systems such as stem-cell and organ-transplant recipients, surgical patients, and critically ill patients in the intensive care unit. "This new approval is important because there is now clinical proof of VFEND's first-line systemic efficacy against...Triple-drug therapy promising against African HIV subtype
...ipheral blood CD4 cells, which help to orchestrate immune responses. After three months, 94 percent of the TB group and 80 percent of the Kaposi group had undetectable HIV RNA levels--rates equivalent to or better than those in studies involving Western patients infected with the B subtype. The decrease occ...Blood protein predicts risk of heart attack
...ding microbes and prepares them for destruction by immune cells. The level of MBL protein in an individual's circulation is genetically determined and can vary drastically from person to person. Several mutations in the gene that codes for MBL result in lower than average concentrations of circulating MBL...Breast reconstruction with implants after mastectomy doesn't hurt survival chances
...gested that breast implants may also stimulate the immune system and reduce blood flow to the breast, thereby impairing cell and tumour growth....Discovery of key protein's shape could lead to improved bacterial pneumonia vaccine
...accine, these pieces of carbohydrate stimulate the immune system to make antibodies against the real carbohy...cteria. The problem with such vaccines is that the immune systems of very young children (younger than two years) do not naturally respond to carbohydrates. P...Tracing the life cycle of a manmade disease
...icles of polyethylene broke off over time. As the immune system reacted against these foreign particles, eventually it would attack and destroy the bone tissue, loosening the implant to the point of failure. It turned out that this complication was an entirely new manmade disease called periprosthetic ost...Old T cells cripple immune function in the elderly
T cells are the weakest link in the immune systems of older people, based on a report by Eaton and colleagues in the December 20 issue of The Journal of Experimental Medicine . The authors show that old CD4 "helper" T cells cannot provide the stimulatory signals to B cells that prompt them ...Animal studies show stem cells might make biological pacemaker
...tance, the researchers don't know why the animal's immune system didn't attack and kill the human cellular "...with the animal's circulatory system to trigger an immune response, but more experiments will be necessary to see whether that's the case and, if so, how that......ncrease early in HIV infection because of profound immune dysregulation. Another possible explanation, they noted, is that those who develop tuberculosis within the first year of HIV infection have a rapidly progressing form of HIV disease. Both the study authors and the editorialists suggested that the res...