Tag: "immune" at medical news

Lab study: Protein delivered via genetically engineered virus slowed glioblasoma multiforme growth

...netically engineered virus increased the number of immune cells in the brain and significantly slowed tumor ...sFlt3L to stimulate the production of fully mature immune cells within the brain," said Maria Castro, Ph.D., co-director of the Gene Therapeutics Research Ins...

Peptide vaccine can produce complete remission in myeloid leukemia patients

...ome patients. The experimental vaccine produced an immune response in 60 percent of patients tested - or 20 ...of Hematology. Of those 20 patients who mounted an immune response against their cancer, 14 had an overall survival of four years, and none of the 13 patients...

Month of birth linked to risk of MS

...th may influence the development of the nervous or immune systems and therefore determine the risk for this disease in adult life, they conclude....

New marrow transplant method developed at Stanford may eliminate fatal side effects

...kemia, but in about half of the cases transplanted immune cells wind up attacking the patient's body, as wel...djusting the patient's level of a specific type of immune cell, the regulatory T cells, before the transplant is done. The method was first developed in mice ...

NHLBI stops sickle cell anemia transfusion study

...therapy. Other risks include alloimmunization, an immune system reaction which can interfere with the benefits of subsequent transfusions, and exposure to blood-borne infections. The STOP II trial, conducted at 23 clinical centers in the U.S. and 2 in Canada, enrolled patients at increased risk of str...

Study shows haploidentical natural killer cells may provide hope for some patients with AML

...py. Natural killer cells are part of the body's immune system. The cells play an important role in defend... the goal of the study was to try to stimulate the immune system of patients with advanced AML to fight the cancer by giving the patients natural killer cells...

VGTI researchers help uncover why aging reduces immune system function

...y have made a discovery that helps explain why our immune system worsens with age. The work was led by Janko...inding ways to slow or stop the degradation of the immune system. The research results are printed in the current edition of the Journal of Experimental Medic...

UCSD researchers identify new role for drugs in prevention, treatment of atherosclerosis

...es that make up atherosclerotic lesions, including immune system macrophages, smooth muscle cells, lymphocytes and endothelial cells, the researchers unexpectedly found that PPAR-alpha and PPAR-gamma drugs worked to inhibit atherosclerosis through different molecular pathways. PPAR-alpha worked in the arter...

Temporary weight gain over the winter holidays... might be a good thing

...ght a little temporary fat actually strengthen our immune systems? Indiana University Bloomington assistant ...studying the relationship between fat reserves and immune function in animal models. So far, Demas has found that sudden weight loss leads to the rapid depres...

Mayo Clinic discovers potential marker for aggressive kidney cancer

...on researchers knew that B7-H1 is usually found on immune cells and is found in some other cancers, but is n...ey. When B7-H1 is expressed, it shuts down the immune system, limiting the body's ability to attack the tumor and perhaps increasing a tumor's ability to ...

Resistin integral part of the inflammatory response

...een questioned because it is primarily secreted by immune cells called macrophages in humans rather than fat...esity. This may mean that obesity in humans causes immune cells like macrophages to overproduce resistin in reaction to the cytokines, thereby promoting diabe...

New treatments for infertility are unjustified

...e offered powerful treatments, such as steroids or immune suppressant drugs, to reduce the levels of NK cells. But the authors argue that, not only do these tests give no useful information about what is happening in the uterus, these treatments are not appropriate for use in reproductive medicine withou...

Study documents decline in rare paralytic disorder linked to influenza vaccination

... (GBS) is a paralytic disorder in which the body's immune system affects part of the peripheral nervous system, according to background information in the article. The first symptoms include varying degrees of weakness or tingling sensations in the legs followed by progressive weakness. Concerns about the r...

FDA grants accelerated approval of TYSABRI, formerly antegren, for the treatment of MS

... MS, inhibits adhesion molecules on the surface of immune cells. Research suggests TYSABRI works by preventing immune cells from migrating from the bloodstream into the brain where they can cause inflammation and poten...

NCI scientists create model that predicts follicular lymphoma survival

..., New England Journal of Medicine *, suggest that immune cells infiltrating follicular lymphoma tumors have...impact on survival--both signatures came from such immune cells. The progression rate of follicular lymphoma, the most common non-Hodgkin lymphoma, varies wid...

Infection in ELBW infants linked with poor neurodevelopmental, growth outcomes

...tion of proinflammatory cytokines [proteins of the immune system], and pharmacologic interventions to reduce the impact of reactive oxygen species on vulnerable oligodendroglial [tissue in the central nervous system] precursors. Ultimately, efforts to reduce the high rates of infection in ELBW infants are t...

Infections in low-birth-weight infants are associated with impaired neurodevelopment and growth

...e brains of newborns. An inflammatory response by immune signaling proteins called cytokines, either in the fetus or amniotic fluid, reflecting an infection in utero, appears to increase the risk for neonatal brain injury. Newborns with infections also are at risk for circulatory or respiratory problems t...

Chemoprevention backgrounder: Working for a future of cancer chemoprevention

...t of COX-2, possibly because of the body's natural immune reaction to the cancer. Lotan found this year that...e, in many researchers' eyes, is inflammation, the immune system's reaction to cell and tissue injury. Cancer often originates at the site of chronic inflamma...

Brain inflammation found in autism

...The researchers found strong evidence that certain immune system components that promote inflammation are co...autism. "These findings reinforce the theory that immune activation in the brain is involved in autism, although it is not yet clear whether it is destructiv...

NIAID launches influenza genome sequencing project

...netic changes that enable them to evade the body's immune response and sometimes become more virulent," says Anthony S. Fauci, M.D., director of NIAID. "This project not only provides a valuable resource for current influenza researchers, it also will attract investigators from other fields. We anticipate t...

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