DNA Imaging to Design Better Drugs
...orking in this area forabout 1 1/2 years. Sponsors include the <AHREF="http://www.cancer.org/">American Cancer Society , the ResearchCorporation and the Analytical Division of the American ChemicalSociety. Both Williams and Bottomley anticipate widespread acceptance andutilization of this assay once...Digital Speech Analysis Tests Sobriety
...ferent people, gathered at IndianaUniversity. They include different types of speech, such as monosyllabicwords, tongue twisters, isolated sentences and passages of connectedsentences. Samples were taken when participants were sober, moderatelyintoxicated (.05 percent blood alcohol level) and highly intoxic...Tacrolimus Stops Rejection Of Kidney Transplants
...lts. Transplant centers participating in the study include the University of Chicago, the University of Alabama at Birmingham, Johns Hopkins, Univ. of Calif. at San Francisco, Mount Sinai Hospital (NY), Univ. of Calif. at Los Angeles, New England Deaconess, New England Medical Center, St. Vincent's Hospital,...Study Shows Major Savings In Supervising TB Care
...ke DOT," says Chaisson. Other authors of the study include Richard D. Moore, C. Patrick Chaulk, Robert Griffiths and Solange Cavalcante. The study was supported in part by Marion Merrell Dow Inc.......ance, our findings have clinical implications that include the need for prompt identification of patients in whom AIDS progresses early and who have the thymic-defect profile," the authors report. High-risk infants may be identified currently by blood test measurements of the joint distribution of their CD4...ACTG 315 Preliminary Results: Drug Cocktail Restores Partial Immune Function
...etroviral therapy (HAART) --drug combinations that include protease inhibitors -- can experiencedecreased plasma levels of HIV, increased circulating CD4+ T cellcounts, decreased risk of opportunistic infections and decreasedshort-term mortality. However, ACTG 315 is the first studyto probe the immunologic ...Childhood Sex Abuse Impacts Adult Relationships
...bjected to exposure, which the researchers did not include as sexual abuse. "These figures, which are fairly representative of the general population, indicate that sexual abuse is quite prevalent among children and young girls," said Feerick, who presented the findings at the American Professional Society...NIAID Stops AIDS Study Prematurely Because Drug 'Cocktail' Boosts Survival
...nt we have available." Others involved at UNC-CH include Dr. Charles van der Horst, associate professor of medicine and director of the AIDS unit; Dr. David Wohl, research fellow in medicine; and research clinician Janet Groves. Nationwide, researchers found 63 "disease progression events" -- including AI...Guidelines Offer Ways To Curb Antibiotic-Resistant Infections
...acilities and educational programs. The staff also include Drs. William Rutala, director, and Dr. David Weber, both professors at the School of Medicine, and Eva Clontz, program coordinator....Substance from Grapefruit Juice May Make Medications Safer
... medications, researchers have found. These drugs include nearly all calcium channel blockers (used to control blood pressure) and some immunosuppressants, sedatives, and protease inhibitors (used to treat AIDS). Although the "grapefruit juice effect" was discovered serendipitously almost a decade ago when...New Drug For Parkinson's Disease Proves Effective, Study Finds
...mitter would. Dopamineagonists on the market today include bromocriptene (brand name Parlodel) and pergolide (Permax).Doctors use the drugs to alleviate symptoms and also to smooth out the highs and lows of motor control that many Parkinson's sufferers experience while on levodopa (Sinemet), the most powerfu...Condemnation May Be Driving Circumcised Women From Health Care
...women, illustrated by casestudies. The guidelines include sample questions American physicians should usewhen examining female patients. "Blanket condemnation by health workers will not help families decidehow to break a long-standing tradition by choosing not to circumcise theirdaughters," the aut...3D Ultrasound Gives Better View Of Brain's Arteries
...nced transcranial ultrasound and 3Dreconstructions include pinpointing cerebral hemorrhages. Thus, Delcker and hisGerman colleagues as well as researchers at Bowman Gray, where Delcker was avisiting professor from January through July, may soon apply the lessons learnedfrom this study of adults to the study...Ultrasound Helps Pediatric Heart Surgeons After Open Heart Surgery
...y in children. His colleagues in the study include Drs. Garry Cornel, chief of theDivision of Cardiovascular Surgery, Lloyd Semelhago, William Splinter, NihalWeerasena, and Lothar Broecker and Guy Millette of the Division ofCardiovascular Surgery and the Department of Anesthesia....NIH Honors Emory Researcher With Merit Award For Work On Renin-Angiotensin System
...g pathways for the entire class ofreceptors, which include those for a variety of critical bodily functions. ACE in Reproductive Biology One of the most interesting aspects of ACE biology is the two differentmanifestations, or isozymes, of the enzyme. The terms for these two differentisozymes-somatic...Planning Researcher Finds Best Neighborhoods Aren't Always Best At Preventing Infant Mortality
...despitepoverty, illiteracy and the effects of race include portions ofRiverside, West Price Hill, Northside, Bond Hill/Roselawn, theEast End/Linwood, and Clifton/University Heights and Fairview. According to his research, these areas should have high infantmortality, but they don't. For instance, a Northsid...Affordable, Hand-Held Biosensor For Diagnostics
...ss of moleculesproduced by invading organisms that include viruses, bacteria, in addition totoxins and allergens. The biosensor was able to detect DNA concentrations at levels of down to9 femtograms per square millimeter. (A femtogram is a millionth of a billionthof a gram.) By comparison, current te...Organ Rejection Drug Also Shows Promise For The Treatment Of Kidney Disease
... The traditional treatments for glomerular disease include steroids givenalone or togetherwith cyclosporine or cytotoxic drugs. Despite the effectiveness of thesemedications, Briggssays, some patients cannot tolerate steroids for long periods, suffer serioustoxicities of cytotoxicdrugs or even relapse when ...Study Finds Incidence Of Stroke Over 40 Percent Higher Than Previously Stated Figures
...cinnati region was 288 per 100,000. This does not include transientischemic attacks (TIAs), often regarded a...ably have higher stroke rates." Co-authors include Thomas Brott, M.D.; Rashmi Kothari, M.D.; RosieMiller, R.N.; Jane Khoury, M.S.; Arthur Pancioli, M.D...Heart Attack Survivors Can Lower Stroke Risk By Taking Cholesterol-Lowering Drug, Study Says
...ts getting simvastatin. CARE, however, did include stroke reduction as a secondary part of itsinvestigation. Plehn says that this part of the investigation makes the CAREstroke analysis more acceptable to statisticians. The team's initial paper in1996 reported a 31 percent reduction in stroke, based ...